“may be significant”

The clinical implications of individual-induced penetration differences may be significant for future implant survival.

In addition, although there may be significant experience in using these existing therapies for chronic immune-mediated diseases in children, there may be little or no experience in using them in patients who would be at the greatest risk from COVID-19 such as infants, those who are otherwise immunocompromised, and those with pre-existing complex medical conditions.

In patients presenting with GI bleeding, bloodwork may be significant for acute blood loss anemia or leukocytosis due to inflammation.

However, if in the course of analysis such information is identified, the laboratory should report female carriers of X-linked recessive mutations associated with childhood-onset disorders, since there may be significant risk to the family for conceiving affected males.

The clinical implications of these study findings may be significant.

Some of these decisions may only concern the member state that is the defendant in a case, but often the decisions may be significant for several member states.

However, none of these studies examined the age at which the relationship may be significant, nor did they examine the associations by sex.

Although regulators of apoptosis proteins are up regulated in almost all cancers there may be significant quantitative divergences concerning the amount of each protein in individual patients suffering from the same disease.

facturing process (the high beneficial residual compressive hoop stresses at the surface are lost due to plastic flow, wear, and material removal at reprofiling): variations in residual stress have been measured [ 25 , 26 ] and some models have considered their influence on RCF damage [ 23 ], which may be significant.

• Increased awareness of JAKi-associated weight gain may be significant for patient counselling and decision making • This study has implications for future exploration of the therapeutic potential of JAKi in cachexia and metabolic disease Conflicts of interest Dr Abu-Hilal has been speaker, advisor and/or received honoraria from AbbVie, Biojamp, Boehringer Ingelheim, Bristol Myers Squibb, Celltrion, Eli Lilly, Galderma, Hikma Pharmaceuticals, Incyte, Janssen, Leo, L’Oreal, La Roche Posay, Medexus, Novartis, Pfizer, Recordati, Sanofi Regeneron, and Sun Pharma.

For example, fish species evolved in well-buffered systems such as the ocean may be more sensitive to variation in pH compared with fish in freshwater environments where seasonal fluctuations in pH may be significant.

As the noncalcitropic properties of vitamin D have been suggested to influence inflammation,hypertension, insulin resistance, and dyslipidemia ( 8 ), the clinical burden of lower serum 25(OH)D concentrations in overweight and obese individuals may be significant.

Complexity of Innate Immune Recognition in Terms of Spatial Distribution of Cellular Targets The activity of early produced cytokines may be significant for bystander cell(s) of the same or different subtype(s) that will recognize the bacterium in the second order.

It is possible that it may be significant.

Ecologists and biologists rarely acknowledge the way beauty biases can affect research, although they may be significant and therefore worthy of discussing.

The implications of saccharin’s behavioral effects and their transgenerational transmission reported here may be significant because saccharin is used extensively in food, drink and pharmaceutical products, since its reintroduction as a “safe” sweetener in the year 2000.

We posit that there may be significant features present within the subset selected through both the PC and RF metrics.

The epidermal cells are also often the first cells to confront invading pathogens, where ROS production is an early response, so it may be significant that it is also in these cells that the transmission of information from the PM by ROS diffusion would be more likely to take place because of a lower background concentration of H 2 O 2 .

This would be the case when the sub-groups show both raised and lowered trait measurements relative to Col-0 thus obscuring the signal even though they may be significant when associated individually.

Additionally, there may be significant postoperative pain and delay to return to normal activity associated with a large open incision.

There may be significant changes in the distribution of the optimal areas for different shellfish species in the medium and long term.

Even a small benefit may be significant due to the safety profile and cost-effectiveness of this class of drugs.

Meyer-Rath and Over argue that future economic evaluation should account for a range of other factors that may be significant determinants of ART costs, including scale and scope of delivery, health states, ART regimens, health workers' experience, patients' time on treatment, and the distribution of delivery across public and private sectors.

This new method may be significant for whole genome analyses, including other viruses.

Therefore, these types of VUS may be significant and valuable to be further studied.