Barely Significant
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“may be significant”

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In the literature

1213 29 , 31 The precise role of CHIS in pandemic preparedness and pandemic responses is currently unclear but may be significant. 16 In the case of Disease X, where the pathogen, route of transmission, associated morbidity, mortality and long-term complications are unclear, the role and value of CHIS are understandably difficult to predict.
As research has shown favourable health effects of co-participation in DMU [ 19 , 21 , 36 , 37 , 38 , 39 , 40 ] and PA [ 30 , 31 , 32 , 35 ], the ecological factors recognised in this study as correlates of co-participation may be significant for children’s health and development and contribute to sociodemographic differences in health.
This observation predicts that the NK cell-mediated anti-leukemia effect would be greatest in individuals with HLA-C alleles lacking NK-Pro activity ( HLA-C * 02, -C * 05, -C * 07, -C * 08, -C * 17 ) and lowest in individuals that possess HLA-C * 06 together with the C2-binding KIR2DL1 inhibitory receptor, a factor that may be significant when choosing donors for stem cell transplantation.
However, there may be significant differences in prognosis even in patients with the same TNM staging and pathological grade after similar treatment [ 7 , 8 ], indicating that KIRC is a heterogeneous tumor, and the existing clinicopathological features and classification are not sufficient to evaluate the prognosis and risk stratification of KIRC patients.