“may be significant”

The risk of kidney function deterioration following transfusion may be significant for patients with IE, who often already have compromised renal function.

( 14 ) confirmed the role of IGF-1 as an important autocrine or paracrine regulator of smooth muscle cell proliferation, and suggested that it may be significant in determining the cellular response in rat aortas after balloon denudation.

Both interventions are known to have a preventive effect and we hypothesize that these effects may be complementary, so that the combined effect may be significant and long-lasting.

[ 33 ] There may be significant differences in baseline characteristics (such as age, underlying disease, source of infection, initial severity), definition criteria of septic shock, sample size, and clinical practice among different regions.

For instance, they assume a free-atom kinetic energy at the transition state and ignore quantum tunnelling, which may be significant for light particles. 63 More critically, they omit energy exchange between the adsorbate and the substrate, which is central to more sophisticated treatments such as Langevin or Fokker–Planck equations. 61,64 This simple hopping picture captures essential features of surface diffusion and holds at

Thus, there may be significant untapped potential in the community for further communication efforts.

29 It should be noted that this relatively minor central BP decrease may be significant in terms of prognosis, given the finding of the ASCOT-CAFÉ study that an intergroup difference of 3.6 mmHg in central BP decreased cardiovascular mortality by 24% and the risk of fatal and nonfatal stroke by 23%. 28 Moreover, the results of the CAFÉ study suggest that certain drugs have an “additional” effect on central BP, which may explain the benefits in terms of cardiovascular morbidity and mortality.

For the remaining cell lines, IFNγ treatment did not significantly affect NK cell-mediated lysis, though some showed trends that may be significant with more donor replicates.

Accordingly, we used a microarray approach to examine the family of FGFs and their receptors, comparing the effects of two different organophosphates, chlorpyrifos and diazinon, to emphasize points of similarity and difference: if the developmental neurotoxicity of the organophosphates involves neurotrophic mechanisms unrelated to the inhibition of cholinesterase, then there may be significant disparities in their impact on neurotrophic factors.

It is well known that (renal) sympathetic nerve activity is increased in CKD patients and that the prognostic consequences of this may be significant (Zoccali et al., 2002 ).

Anxiety about endoscopic procedures may be significant obstacles for patients attempting to adhere to their appointments.

19 20 Inaccurate perceptions of provider quality may be significant for pregnant women because obstetrical and newborn complications are rare, and the technical skills of maternity providers are hard to observe.

As a result of the possibility of aggregated risk factors for metabolic syndrome, the association between cardiometabolic diseases may be significant.

The hypothesis stating that the diet of an individual may be responsible for increasing or reducing the risk of incidence or onset of essential tremor may be significant.

Therefore, we considered that body composition and fat mass may be significant influencing factors in the study of the association of sarcopenia with OA.

The reported associations between smoking/caffeine consumption and higher migraine frequency support the notion that both smoking and caffeine consumption may be significant triggers of migraine attacks [ 42 ].

These signatures may be significant for diagnostic purposes and for classifying SSD, MDD, and healthy controls.

Finally, the components of YYTN related to antioxidant activity were determined by correlation analysis, which may be significant to the research of the therapeutic material basis of YYTN.

There may be significant differences between the response of human keratinocytes and those of other mammals.

The poor intergroup consistency indicates that there may be significant differences in measurement among different doctors in each measurement, which can lead to a large deviation in clinical practice [ 22 , 23 ].

55 Control of such conditions may be significant to maximizing the uptake of heavy metals. 3.2.

Therefore, our finding that the concomitant use of an SGLT2i does not suppress the therapeutic effects of tirzepatide may be significant.

There are also costs associated with collecting (often 1 L) and transporting large numbers of samples to laboratories that may be significant distances away ( 67 ).

This study may be significant for searching effective drugs of AIS, and the therapy of vascular cognitive impairment.

The clinical impact may be significant, as nearly 50% of pediatric AML can be assigned to molecular categories characterized by HOX gene deregulation, including many high-risk categories.