“may be significant”

The latter may be significant for identifying targets and designing putative inhibitors, and it could be invaluable towards shedding some light into the pathways of oligomer formation in amyloid disease.

cholerae that may be significant in preventing infantile diarrhea.

Because gut microbiota is closely related to ASD, our results may be significant despite that limitation.

The mechanism by which IGFBP-3 mediates these mitochondrial effects is still unclear and may be significant for the development of novel therapies for certain mitochondrial diseases.

These findings may be significant in light of future trials involving yet more sophisticated closed-loop systems and in which equipoise regarding the two study arms may be yet more imperative (see Discussion ).

However, this targeting method frequently was not able to localize the DLPFC as there may be significant variability in functional localization for this area within the PFC as a whole ( 70 ).

We herein report this rare case since its clinical course may be significant in suggesting a relationship between NTS and early postoperative recurrence of malignancy.

GA that develops away from the CNV had approximately half of the growth rate, suggesting that there may be significant differences between these two types of GA [ 23 ].

In this connection, the recent characterization of a key role for the electrostatic environment of the chromophore in controlling photoprotein fluorescence yield may be significant. 73 Conclusions We have synthesized a novel nonplanar form of the GFP chromophore, I , and investigated its photophysics.

In this context, understanding stressors and perceptions of workplace preparedness may be significant when designing interventions to support HCW involved in cancer care as we continue to live with COVID-19, and in future periods of uncertainty and rapid change.

68 Given the predilection of SARS-CoV-2 towards populations with demographic risk factors (e.g., aged population and male) and comorbidities similar to those of IPF, the burden of development of long-term fibrotic consequences may be significant.

An interesting question then rises, do these mutations affect gene expression programs and if so how? Thus, although the differences are small, they may be significant and merit further study.

The impact of removing testis, especially in young men, may be significant.

These results may be significant because several studies have reported that in vivo ATL tumor cells can produce IL-2 or IL-15 and express the high affinity IL-2 receptor α chain, CD25.

The observation that the amplitude of TW is larger compared to other types of parkinsonian tremors may be significant from a clinical point of view.

These results do not align with the existing literature, suggesting that there may be significant issues with the reliability of self‐reported surveys.

The dynamic normalization is expressed as (11) T ( t i ) T ref ≅ 1 n ∑ k = 1 k = n I meas ( t i , c k ) I OB ( t i , c k ) 1 n ( b − a + 1 ) ∑ i = a i = b ∑ k = 1 k = n I meas ( t i , c k ) I OB ( t i , c k ) ≅ ( b − a + 1 ) ∑ k = 1 k = n I meas ( t i , c k ) ∑ i = a i = b ∑ k = 1 k = n I meas ( t i , c k ) ≅ ( b − a + 1 ) I meas ( t i ) ∑ i = a i = b I meas ( t i ) This formulation does not explicitly treat the effects of incoherent scattering from the sample, which may be significant because of the short sample-to-detector distance used in this study (~5 cm for the CT scans, ~10 cm for the high-speed imaging).

Application techniques are difficult to standardize and there may be significant intraoperator differences.

Artificial photosynthesis systems do not have this restriction, and there may be significant advantages in alternative water oxidation approaches, such as faster reaction kinetics and more valuable oxidation products. 27,28 For example, hydrogen peroxide can be used for metal-peroxide batteries, 29 disinfectant, or bleaching agent. 30–33 Though hydrogen peroxide can be formed by oxygen red

With a larger sample size, there may be significant differences among all severity groups, whether using GOLD or STAR.

Data of the present study indicate that formation of dimers, hexamers and higher oligomers may represent a strong intrinsic assembly property of the viral core NEC that may be significant for later steps of binding activities and regulation.

These phytochemicals may exhibit anti-amyloidogenic, anti-oxidative, and anti-inflammatory effects, with special focus on molecular targets which may be significant in safeguarding neurons against AD.

Spin-orbit (SO) interaction was not included in the calculations, although it may be significant for the Co ions, in particular, in the context of topological properties [ 47 , 48 ].

We are able to distinguish different types of structures, including oligomeric assemblies and mature fibrils, and observe a number of morphological differences between the species formed in vitro and in vivo , which may be significant in the context of disease.

The frequency of treatment failure may be significant in patients treated with MIL, which has supplanted antimonials in the kala-azar extermination campaign in nations such as India, even though it has been noted in patients treated with the majority of anti-leishmanials.