Barely Significant
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“may be significant”

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In the literature

The possible future wide-scale implementation of the malaria vaccine RTS,S/AS01 in young African children is unlikely to play a major role in the containment of artemisinin-resistant malaria strains initially, but the contribution to reduction in antibiotic use associated to febrile episodes may be significant 27 .
In general, the differences do not have significant impacts on a physician prescribing medication or treating a condition, but in some cases there may be significant differences between one manufacturer’s drug instructions and those of another, which has the potential to impact a patient’s health.
Mortality rate, although significantly lower than the previously reported range of approximately 60%, continues to be unacceptably high in the 20-40% range.[ 22 ] Chronic sequelae of end-organ dysfunction may be significant.
Amniotic fluid embolism.
Int J Crit Illn Inj Sci · 2013 · PMC3665120