“may be significant”

This may be significant in terms of establishing appropriate concentration gradients for chemoattractants that direct cells to the luminal or subepithelial compartments.

Although the maximum ventricular wall thickness can vary and may be significant, it is infrequently associated with left ventricular outflow tract obstruction [ 54 ].

We analyze genome-wide sequencing data from fifty dogs, including obese and nonobese individuals, and use bioinformatic methods to select polymorphic sites that may be significant for obesity-related traits.

Therefore, if older age groups underwent more extensive examination, there may be significant associations that were not readily apparent in our analysis.

Notably, the burden of cancer symptoms may act as a barrier to physical activity participation for some people with MBC, whereas for others, there may be significant interest in physical activity programming despite marked symptom burden [ 29 , 33 ].

Although the probability of contamination may be significant, the role of MSm as a pathogen in our patient is possible.

Thus, the local temperature of the affected limb may be significant.

It is unclear if one or two percentage points may be significant enough to conclude any causal relationship between food environment and obesity prevalence.

Static ALFF and dALFF exhibited significant spatial overlaps and temporal correlation in the precuneus and MTG in EOS, suggesting that these regions may be significant in the onset and development of EOS.

Furthermore, LMM is increasing faster than any other melanoma subtype; thus, these challenges may be significant in the future [ 146 , 147 ].

Finally, deflation of the endotracheal tube cuff may help eliminate CO 2 by allowing the front of fresh gas to be advanced to the distal end of the endotracheal tube, allowing a slight reduction of the anatomic dead space, which may be significant in situations when the V t is small.

It may be significant that cancer cells have a higher expression of anionic molecules such as phosphatidylserine 42 , 43 and O -glycosylated mucins 44 , 45 than normal cells, resulting in a net negative charge of cancer cell membranes rendering them more attractive to cationic molecules.

This relatively rapid response may be applicable to typing of determinants in the major histocompatibility complex that are not equivalently identified by alternative analyses, and may be significant in tissue transplantation.

This study shows that BP and BP-3 concentrations in sunscreen creams vary considerably and may be significant even in items marked as being free of oxybenzone or octocrylene, raising ongoing concerns about dermal exposure ( Fig. 6a ). 29 Thin-layer chromatography was used to extract benzophenone-4 (10, BZ4) from hair shampoo's surfactants, colors, preservatives, and other ingredients.

There may be significant selective pressures favoring divergent NSP2 genetic or protein content [ 44 , 47 , 48 ].

young trees of Spruce or Black Elder), which may be significant for differences in nest concealment and anti-predation sheltering.

These simplified systems may exclude potentially important corrosion mechanisms that may have negligible effect over days or weeks but whose cumulative impact may be significant over the long-term.

The overall survival obtained with these regimens is 70 to 80 % but there may be significant risks of secondary malignancies and cardiac problems due specifically to the radiotherapy component of treatment, which has prompted attempts to reduce these problems with dose-adjusted regimens[ 1 ].

It may be significant that these 2 instances were also the only times that the Middlebrook-Dubos titer could be brought down to 1:8.

Moreover, melatonin has been shown to exhibit anti-inflammatory properties, a factor that may be significant in light of the evidence of inflammation observed in some individuals with autism spectrum disorders (ASD) [ 5 ].

The latter may be significant to consider during the colder seasons in Norway, during which people tend to stay indoors.

Furthermore, there may be significant group differences in teachers’ autonomous learning ability.

We surmise that if we have a larger sample, this relation may be significant although weak.

As such, there may be significant risk that such biologic product may create immunogenicity due to modification in manufacturing processes and other unforeseen changes compared to its original production.

Intriguingly, a specific clone of CAFs associated with ECM (eCAFs) is identified in pancreatic cancer [ 339 ] and gastric cancer [ 340 ], and recently identified Endo180 and paired related homeobox 1 (Prrx1) may be significant genes associated with the function and plasticity of eCAFs [ 341 , 342 ].