“may be significant”

There may be significant advantages in using this technology in adolescent screening programs with positive impact on sensitivity and specificity. 3 , 4 , 6 – 9 This study describes the successful introduction of UPE in the workflow of an established adolescent cardiovascular screening protocol.

However, the role APOE ε4 in aging independent of AD pathology may be significant [ 33 ], as a small but growing body of evidence in both cognitively unimpaired humans and rodents shows that visual working memory and learning is better among APOE ε4 carriers than noncarriers [ 34-36 ].

This study was part of a larger investigation of the influence of geographical access on survival from cancer, and these cancer types were chosen because they are sites where early intervention is known to affect outcome, or are sites where earlier studies have suggested access may be significant.

This is not uncommon, because bone destruction can occur secondary to pressure erosion;[ 4 ] particularly the destruction may be significant in the paediatric age group.

However, the positive effects of increasing colostrum dosages could not be proven in pigs treated with chemotherapy and fed a normal milk diet [ 95 ], showing that both the dosing regimen and the control diet may be significant.

Because there may be significant benefits to individuals and to society as a whole that are not reflected in the device pricing, there exists a potential loss to patients and to society that may not be recognized if and when devices and therapies are not commercialized due to the apparent insufficient ROI to investors.

Such a direct coupling between adhesion receptors by means of intracellular signals may be significant for the coordinated interplay between cell–cell and cell–substratum adhesion that occurs during embryonic development, in wound healing, and during tumor invasion and metastasis. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-pro

The Model F-value of 21.23 indicates that the model may be significant.

The consequences of diabetic alterations may be significant for the development and function of the placenta [ 30 ].

The reason may be significant differences in ferrocene oxidation and poly [Ni(salcn)] in the second step.

Thus, the enrichment of potential urologic pathogens in the renal function decline group may be significant.

However, since thicker and low-density substrates are usually chosen to increase the bandwidth and the gain of a microstrip antenna [ 12 ], the surface wave contribution may be significant. 3.

However, the mean value equal to 0.24 (the highest value among the domains) and the quartile values (the first one is 0 and the third one is equal to 1) indicate that difficulties with preparing game meat may be significant for many people.

Furthermore, IRE cannot be avoided, mostly in the periphery of the electrodes; therefore, contribution of IRE in cell death may be significant, but it may still be tolerated for ECT. 31 Taking this into consideration, pairs of needles in the different electrode arrays were sequentially set to voltage until all combinations of unique pairs were activated, setting boundary conditions for voltage as an anode and a cathode during each simulation.

Note that as a consequence of the Al filter used in front of the detector, in the case of B targets only the Bremsstrahlung emission is observed (as B has no lines above 1 keV); however, in the case of Au the M-band contribution may be significant.

Such an ecological strategy may be significant in areas harboring multispecies weed communities.

Obviously, this has potential for forming a stem-loop structure, and it may be significant that a short sequence a few nucleotides upstream, TCAAAA, has the potential for competing with this to form a short hairpin with the TTTTGA at the end of the palindrome.

All in all, these peculiarities in the dinucleotide UCNE compositions may be significant for changes in the DNA double helix structure, which is the focal discussion in Section 4 below. 4.

For heavy calcifying species such as Calcidiscus leptoporus and Coccolithus braarudii , the POC associated with coccoliths (e.g., Figure 3b,d ) may be significant yet remains an uncharacterized contribution to POC export that is inextricably linked to coccolith PIC export.

However, there may be significant differences between mean hearing thresholds determined though automated audiometry and manual audiometry [ 12 - 14 ].

Additionally, interobserver variability and the requirement for high operator expertise may be significant barriers to consistent interpretation, particularly when MRI scoring systems such as VI-RADS are applied outside specialized academic centers [ 9 , 36 ].

The presence of thyroid antibodies among new-onset T1D patients occurs to be a common phenomenon, which may be significant for predicting the possible clinical manifestation of AITD at the same time of setting the T1D diagnosis ( 37 ).

Our data raises the idea that BRCA1 Q356R may be significant in the context of other variants that weaken DDR.

Only a small number of patients with partial STAT1 deficiency have been identified, but it may be significant that none has had HSE [ 96 , 97• , 98 ].

Diabetes reinforces the association between PD and CKD through multiple mechanisms, and early control of blood glucose and periodontal inflammation may be significant in preventing or delaying the progression of CKD. 5 Clinical interventions for targeted therapy of PD to treat and delay CKD development The occurrence of PD is chronic inflammation mediated by the oral microbiota.