“may be significant”

Increased expression levels of Atg8h, Atg11, and Atg18d genes were found in the isolated secondary xylem cells in comparison to the primary stem cells, implying that activation of these genes may be significant to dPCD [ 89 ].

While CXCL12 expression is associated with a favourable prognosis in an analysis of all breast cancers, there may be significant heterogeneity in the impact of CXCL12 on tumour behaviour between subtypes.

This study, deliberately designed to evaluate the effectiveness of a mood stabilizer in pathological gamblers with comorbid bipolar spectrum features confirms previous reports of the effectiveness of these compounds in PG, and suggests that there may be significant advantages in subtyping pathological gamblers.

This can result in a loss of whole-brain spatio-temporal pattern information that may be significant in association and prediction analyses.

The results showed that genes, type of depression, ethnicity, and significance may be significant covariates of heterogeneity among studies.

Our analysis, however, is subject to several important limitations: Due to data constraints, we excluded some NCDs for which overweight and obesity-attributable costs may be significant.

The effect of hemolysis may be significant in breeds with K + -rich red blood cells.

This may be significant, because many studies have indicated that Asian patients treated with antiplatelet or anticoagulant medications have a higher risk of bleeding than those of European descent. 21 Further analysis of the timing of major bleeding events in our patients revealed that the events primarily occurred within the first 3 months following the index ACS event.

These findings suggest that TREK-1 and TASK-2 may be significant regulators of human gastric muscle and vascular motility.

ANOVA was performed at the berry level ( n = 24) followed by Tukey's HSD test (p ≤ 0.05) and determined soapberry (23.21 mg/g) had higher levels (p ≤ 0.05) of arabinose than black huckleberry (5.48 mg/g), which may be significant for diabetes control as arabinose has been shown to slow down glucose absorption by inhibiting the intestinal enzyme sucrase, which is critical for hydrolyzing sucrose into glucose and fructose molecules.

Even though this trend may be significant when testing the larger patient groups, TT may be more suitable for identifying bulbar impairments in the patient groups rather than differentiating between patients with ALS and controls.

Such amygdala engagement may be significant if it includes its major output center, the central nucleus (CeA), which promotes the rapid generation of behavioral, endocrine, and autonomic responses 18 .

Statistically, the differences may be significant.

However, there may be significant differences among countries in job availability.

As the presented results were obtained by using the commonly applied and valid questionnaire [ 47 ], in a national sample of adolescents, gathered by sampling in all the regions, the findings of our study may be significant for further public health policy.

showing that a 1% reduction of LV pGLS in patients with heart failure with reduced EF was associated with increased mortality: hazard ratio = 1.15 (95% confidence interval [CI] = 1.04–1.27, P = 0.008), 36 a 0.9% improvement of LV pGLS in patients with SSc-PAH may be significant in terms of improving survival.

Similarly, broader societal impacts, including work productivity loss, caregiver burden and education disruptions, were not accounted for, which may be significant for PwSHA.

It has been suggested that general improvements in insulin sensitivity in people with T1D may be significant enough to improve symptoms of retinopathy, neuropathy, and other complications [ 54 ].

However, it has been suggested that there may be significant local differences in allele frequencies and haplotype structure between the Ashkenazi population and other European populations, including at loci associated with common cancer ( Gold et al , 2008 ; Olshen et al , 2008 ; Price et al , 2008 ; Tian et al , 2008 ).

This suggests that the complete CTLH E3 ligase complex is not broadly differentially expressed in disease, but there may be significant alterations of specific subunits.

Nursing mothers may have to limit amount of breast milk intake as distribution may be significant.

While these novel star alleles are rare across sub-Saharan Africa (see Table S5 ), the combined potential impact of rare allelic variation on precision medicine strategies across Africa and in global settings may be significant.

Under mating disruption, where pheromone is continuously applied to the crop, in some cases for 100 or more days [ 2 ], we presume that the propensity for pheromone exposure and this type of learned response may be significant, depending on the average airborne pheromone dosage of pre-exposure.

The peripheral dose due to MV‐CBCT imaging, although small compared to the dose from the MV treatment beam, may be significant if the MV‐CBCT procedure is applied daily and, therefore, should be taken into account when planning IGRT using MV‐CBCT technology.

Inactivation of Notch signaling and expression of ASCL1 may be significant for SCLC carcinogenesis.