“may be significant”

As a consequence, underreporting may be significant [ 2 ].

Still, the advantage by gaining time may be significant, because earlier treatment improves outcomes of SBP [ 6 ].

Our study suggested that volumes over 60 cc may be significant for acute grade 3–4 GU toxicity.

While other RNAs were not found to be enriched within two orders of magnitude relative to DMPK RNA, the additive effects of “mild” off-target engagement in the context of an organism may be significant, depending upon the nature of the target.

Although we hypothesized that there may be significant individual differences in the size and number of the nutrient foramina, and our results have also verified this hypothesis as reasonable, we have not found any related papers and this is a limitation of the study.

Thus, we postulate that there may be significant complexity of the regulatory mechanisms of AhR on TGF β 1 signaling with coregulation of multiple other pathways.

While it is reasonable to assume that these resources may be significant, it is likely that due to the very nature of the activity in question it is the resources used by the caregiver him- or herself that constitute a significant majority of resource utilization.

Combined with anecdotal data from the interviews and the authors’ vast clinical experience with members of the Bedouin community, findings will be discussed in terms of several major themes that may be significant for culturally relevant interventions.

In such circumstances, the risk of deterioration during transfer may be significant and transfer may be impractical [ 52 ].

This modification may be significant, since some of the nitrosated proteins such as the MMDA receptor, cascade inducers, and transcription factors are receptors and might represent other signaling pathways.

Overexpression of PLK2 and PLK3 in DA neurons induces endogenous Ser-129 phosphorylation of α-Syn; however, its survival is not impaired, and the effect of functional phosphorylation on the interaction of α-Syn with specific protein chaperones may be significant and highly site-specific [ 68 ].

One of the consequences of autophagy aberrations may be significant accumulation of Aβ 1–42 in aged OXYS rats’ retina [ 23 ].

These findings point to T2D genes that are differentially expressed and may be significant in the development of breast cancer.

Taking account of nighttime air temperature, commercial and business/industrial areas may be significant determinants of air temperature throughout the year, while residential areas are the main factors during spring and summer.

When evaluating the performance of SVM with two different kernel functions on a given data set, there may not be large difference in terms of classification accuracy, but there may be significant difference between two different kernels in the number of stored support vectors or training time complexity [ 33 ].

Nonetheless, although this loss may be significant, the sufficiently gain-seeking audience enjoys the pleasant preemptive information to a far greater extent, so the loss associated with the ultimate revelation of the bad news can be dominated.

A further exploration of these variables may be significant in designing interventions for youth at an early stage.

23 This finding suggests that clonal evolution of these tumors may be significant, and elegant genomic work has highlighted how these processes might drive relapsed or refractory disease. 10 Although the trend toward a worse outcome in patients with multiple mutations in the COG cohort is intriguing, this observation was not replicated in the UK cohort and may be confounded by the different therapeutic regimens that the patients received.

20 Thus, the order in which bevacizumab plus chemotherapy and EGFR‐TKIs are administered to patients harboring EGFR mutations may be significant.

Thus, a certain proportion of patients may not actively seek, or may not even formally need, treatment, but the size of this proportion is unknown, and even in patients, who self-recover, the harms related to the gambling problem still may be significant.

The differential effect of glucose and sucrose on the expression of MIR156A-GUS and MIR156C-GUS may be significant in this regard.

Conclusion The analysis confirms that risky situations may occur when a patient carrying a hip implant undergoes an MRI exam and that, in some cases, the gradient field heating may be significant.

Even if the intervention has not been found effective to improve functional outcomes (ADL), our findings suggest that there may be significant cost savings given the reductions of hospitalization.

For example, all the protist taxa identified in lichens we sampled in Ohio USA depend on silica for growth and construction of their cell walls, this could suggest that silica-rich lichen symbionts may be significant in the biogeochemistry of the lichen symbiosis.

Inactivation of Notch signaling and expression of ASCL1 may be significant for SCLC carcinogenesis.