“may be significant”

Interestingly, these findings may indicate that MMP-2 expression is not independent, and imbalances in the MMP-2/TIMP-2 ratio may be significant in the pathogenesis of ocular hypertension in glaucoma [ 171 ].

These results indicate that the abnormal expression of miR-214 may be significant in colon cancer. miR-214 overexpression inhibits colon cancer cell viability and colony formation To investigate the functional role of miR-214 downregulation in colon cancer, cell viability and colony formation assays were performed to analyze cell growth.

Antibody cross-protection between the two B lineages is assumed to be low [ 4 , 38 ], although some studies suggest cross-reactive serum antibodies may be significant [ 39 ]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338745/ (accessed on 20 March 2022)—CR16 Under experimental conditions, the B Yam lineage may induce cross-antibody responses to the Victoria lineage, but the opposite is not as efficient [ 40 ].

These may be significant factors for difficulties in performing activities of daily living. 4 – 9 SSc affects both physical and mental health-related quality of life, 10 which may cause problems of functioning and restriction in participation in society.

However, clinically, a recent study suggests that patients on long-acting GLP1-RA have a significantly higher proportion of gastric residue in comparison to the non-GLP1-RA treatment group measured by EGD in patients with diabetes, indicating that the effect on gastric emptying even for a patient on a long-acting GLP1-RA may be significant [ 6 ].

If a leaf is modified to increase S m it could potentially limit the capacity to transport water, and while this may not be hugely consequential for a well-watered plant under water stress these cells could rapidly desiccate and there may be significant limitations to rehydration.

However, in light of the above-mentioned facts about company demographics, there may be significant changes in the role of distressed acquisitions in recent years.

Non-denitrifying populations with a broad range of metabolisms and habitats may be significant contributors to the mitigation of N 2 O emissions. 5) Aerobic ammonia-oxidizing archaea ( Fig. 1 [5], Table 1 ) Ammonia oxidation, the first and rate-limiting step of nitrification, was considered to be performed mostly by certain groups of chemolithoautotrophic Proteobacteria (genera Nitrosospira , Nitrosomonas , and Nitrosococcus ) for more than one hundred years ( 44 ).

Hence, the early detection and treatment of OSAS in these patients may be significant.

Conclusion In conclusion, the results of the present study indicate that specific prenatal and perinatal factors related to disordered neonatal brain function, such as prematurity and IUGR, may be significant and independent predictors of the severity of GDD in cases without definitive etiologic yield.

However, such a high value of P CR / P th is at odds with the picture of turbulent acceleration, and the feedback from CRs to MHD turbulence may be significant.

A careful look at our work, shows that it may be significant in public health issues through occupational exposure considering the work of Orisakwe et al [ 17 ] and that of Vitayavirasuk et al [ 63 ] which shows that subjects exposed to heavy metal in a paint factory and automobile paint spray may have compromised health status.

Recent attempts to develop more phenomenologically defined subcategories of AVH should not overlook the diversity of voices that may be significant in BD (McCarthy‐Jones et al., 2014 ).

ARDWG recommends that, considering that pollen data are not yet comprehensive for all areas across South Africa based on early pollen monitoring data ( 14 ) and the SAPNET website ( https://pollencount.co.za ), other allergenic pollens, such as those from trees and weeds, may be significant in specific regions, and a local common aeroallergen should be considered ( 41 ).

What remains less documented is how breast cancer is understood and experienced from a non-lived experience by Black women as this would provide insight into background cultural and contextual factors around cancer, and breast cancer in particular, that may be significant influencing aspects for better detection and successful management of breast cancer.

There may be significant opportunity for external funders and conveners, including CMS, to help support those states interested in strengthening consumer engagement efforts, by sharing agency experiences and best practices and providing technical assistance.

In contrast, there may be significant selection pressure between clones in vivo, as Ag depots recede over the course of the response.

It is widely accepted that VIP values greater than 0.85 indicate that the dependent variable is “important.” The VIP values of the independent variables both exceeded 0.85, and they may be significant driving factors of Wuhan’s CF (Additional file 1 : Fig.

When voter turnout is higher, i.e., people from low socioeconomic status and minorities participate in elections, the effects on electoral outcomes may be significant [ 1 ].

Hence, DEX may mediate the remodeling of local RAS signaling, which may be significant in overall survival and disease-free survival.

Considering the subjective form of satisfaction as a basis to select the platform in clinical application situation would provide a cloud of information that there may be significant gaps or risks of inaccuracy.

Further, provision of funding and policy-level support provided to schools may be significant to both initial implementation and longer-term sustainability (Durlak & DuPre, 2008 ).

The health impact of this may be significant considering that women of color continue to have higher rates of cesarean section, the health benefits of vaginal deliveries are well known, including lower rates of surgical complications, and black women, in particular, have higher rates of maternal mortality 35 .

These data suggest that MBD3 can enhance the transcriptional repression of CDKN1A by FBI-1 and that the FBI-1-MBD interaction may be significant in cell cycle regulation by repressing p21 expression.

Note that it is difficult to obtain other omics (such as scATAC-seq, snmC-seq, and lncRNA-data) that can be paired with scRNA-seq data, and there may be significant technical and biological noise between different omics of single-cell sequencing data.