“may be significant”

Off-stoichiometry formulation and elevated ambient cure temperature significantly increased system average void volume while fractional free volume decreased, which may be significant for the barrier properties of the final coating.

Tumor necrosis factor-α (TNF-α) secretion was inhibited by ICAM-1 antibody in infected-16HBE cells, suggesting that positive feedback between TNF-α secretion and ICAM-1 expression may be significant in exacerbated inflammation.

This also means that significant cell types may be significant for two reasons: (1) either they are driving a phenotypic association (truly associated); or (2) they appear associated because they share overlapping gene expression with a cell type (or types) driving the associations.

As such, they reported significant adsorption of microcystins by weathered microplastics despite using large particle sizes (3–5 mm), suggesting that adsorption of microcystins by microplastics in natural waters may be significant despite minimal adsorption observed in the laboratory. 4.

Due to locus heterogeneity at the -794 CATT 5-8 microsatellite, genetic association studies in small cohort studies may be significant at the -173 G/C but not at the -794 CATT 5-8 site.

Unfortunately, even with drains, the clinical burden of a POPF may be significant.

Thus there may be significant gaps during a period from about 1914 to the 1930s.

Overall, if a novel ion channel model is developed but no validation is performed, given the numerous issues described above there may be significant uncertainty regarding the true predictive capability of the ion channel model.

The discrete expression of EphA7 on ependymal cells is also of interest and may be significant in the maintenance of ependymomas.

The exact impact of these segments is unclear, but may be significant [ 47 ].

(Patient at a Tunza Facility, Eastern, Kenya, Q2) Even for the poor, these benefits may be significant enough that it is worth finding a way to make the costs of private care viable.

The use of these agents is discouraged in patients suffering from liver, renal, or heart disease, and in those receiving medications with which there may be significant drug–drug interactions [ 27 ].

The presence of retained metalwork, in the form of either metal suture anchors or broken screw shafts, or large bone voids, left as the result of biocomposite implants, may be significant.

However, slight changes in grid resolution may increase or decrease the similarity between the characteristics of the prediction pixel and the observation site, so there may be significant flux in the relationship at small intervals.

Although surgery on these patients is generally performed with minimally invasive techniques, there may be significant blood loss that requires allogenic blood transfusion.

The effect of sorption to sediments and particulates during in-sewer transport may be significant, particularly for organic compounds that have high octanol-water coefficients ( McCall et al., 2016 ).

While the precise implications of the nature of host-environment microbiome sharing in captivity compared to that in the wild are unknown, an increased incidence of disease in urbanized humans as well as in captive animals compared to their wild counterparts suggests that the consequences may be significant ( 15 ).

Appropriate interactions that affect the expression of PTEN may be significant in the development of the disease.

However, it is important to bear in mind that a significant digital division remains and that there may be significant differences due to generational, cultural, or even resource availability issues.

Note that it is difficult to obtain other omics (such as scATAC-seq, snmC-seq, and lncRNA-data) that can be paired with scRNA-seq data, and there may be significant technical and biological noise between different omics of single-cell sequencing data.

Conclusions c-erb-B2, EGFR, mTOR, ERCC1 overexpression levels, and loss of p27 may play roles in hepatocarcinogenesis and may be significant predictors of aggressive tumor behavior.

In the absence of other neuromuscular disease, mitochondrial abnormalities in muscle biopsies below the current 2% cut-off may be significant.

Therefore, there may be significant publication biases.

smegmatis as a model for MTBC [ 32 ], Cas2 [ 33 ] by itself was shown to be deleterious to Mycobacterium survival, thus it may be significant that deletion of cas1 was always accompanied by deletion of at least cas2 .

There may be significant inter-observer and intra-observer variability with poor repeatability and manual processing is laborious and time-consuming.