“may be significant”

The information obtained from the genomic analysis of PEH using NGS may be significant for the planning and monitoring of treatment for this disease.

23 The prevalent paradigm in Canadian pain medicine is under pressure, the need for evolution is clear, and the pivotal issue is eloquently stated in the McMaster’s evidence brief: While there may be significant costs associated with preventing and managing chronic pain (many of which are not covered by provincial health insurance plans), failing to do so using evidence-based approaches may incur even greater costs.

According to the authors, “impulse impact accelerates the generation and propagation of tiny cracks in the workpiece material, which reduces the binding force inside the grains of the material.” Although this may be significant in reducing and eliminating the size effect in micro-milling, an in-depth analysis will be necessary for future work.

As CD24 is also carried on extracellular vesicles, the ability to act in cis or in trans with many partners may be significant for its functions.

Current studies have been conducted on animal and cell models, and there may be significant differences in the aging process and immune system between species that could limit the applicability of these findings to humans.

ters the skin in stage 1 and overestimate the chemical mass that exists the skin in stage 2; and (4) the mass percentage of the target chemical in the product liquid is constant during the liquid emission process, thus the prediction error in the emission profile depends on the product formulae and may be significant if the product contains ingredients that have diverse volatilities.

In terms of sex and age, there may be significant individual differences in the distribution of the compartments.

Consequently, despite the much smaller contribution of neutrons to the total absorbed dose compared to the photon component, the biological effect of photoneutron interaction on healthy tissues may be significant.

This suggests that the regulatory pathway between ZIC2 and OCT4 may be significant for the stabilization of stemness-like state.

This suggests that the measurement index of AS and the elderly population may be significant factors contributing to heterogeneity.

30 , 31 Examination of the soft tissues may be significant for ecchymosis in the posterior ankle and plantar aspect of the foot, along with a palpable gap in the Achilles tendon proximal to the calcaneus. 32 , 33 It is important to rule out concomitant injuries by carefully palpating surrounding joints, muscles, and ligaments.

Our small sample size likely limited our ability to detect some significant effects, meaning that null findings, including those trending toward significance, may be significant with greater power.

An explanation for the high incidence of malignant tumour disease as a cause of death of critically ill patients after hospital discharge may be significant critical illness-associated immune suppression, which is known to have permissive effects on tumour growth and progression [ 42 ].

Since pseudoprogression has been reported with nivolumab [ 16 ], the effect of prior pembrolizumab treatment may be significant.

( 2015 ) provide evidence supporting an earlier speculation (Turich et al., 2007 ) that MG II may be significant contributors to tetraether lipids in coastal and open oceans.

Although blanket and camp ACD unit costs were eight times higher than index case-based ACD, it remains a valid strategy for two reasons: 1) it targeted high-incidence areas and may actually be more beneficial for low-incidence areas, and 2) the value of detecting additional cases early may be significant enough to support the high initial investment necessary for reaching EPHP.

As that research suggests, the psychosocial impact of whether or not a woman is conscious at this moment of separation may be significant for how she experiences this event and adjusts to its aftermath.

Consequently, the tumor-immune characteristics of FTC may be significant in its pathogenesis and offer a potential avenue for immunotherapy.

In animal model studies, irisin has been shown to promote osteoblast differentiation, and inhibits osteoclast differentiation by activating the Wnt/β‐catenin signaling pathway in MC3T3‐E1 osteoblast cells, indicating that irisin has a positive regulatory effect on bone metabolism and may be significant in preventing the development of osteoarthritis [ 129 ].

Our study demonstrated that eight weeks of CrM supplementation in conjunction with resistance and plyometric training produced a significant increase in vertical jump performance from baseline in the Abalakov power test compared to training without supplementation, while other tests had medium-to-large effect sizes suggesting those findings may be significant with a larger cohort of athletes studied.

This result highlights the complexity of oxidative and reductive stresses and potentially indicates that ROS production’s specific source may be significant, and the link between DNL and ROS production, notably in vivo , requires further investigation.

The relationship between these tissues reinforces the LHBB tendon and may be significant in the treatment of tendinopathies affecting any of these muscles.

The fact that the p53 transcription factor activates Bax expression and inhibits the Bcl-2 protein, which leads to conditions promoting apoptosis, may be significant in the disease of the vessel wall [ 79 , 80 ].

Likewise, we expect that there may be significant inter-observer variability in CTA measurements of the aortic annulus.

If the model fits well, it indicates that there may be significant common method bias.