Barely Significant
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“may be significant”

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In the literature

Our results suggest that being able to perform object control skills (such as catching, throwing and kicking) competently in childhood may be significant and influential in building a positive perception of sports competence, in turn increasing adolescent physical activity engagement and fitness levels.
Although the extent of the non-classical phenotype may be initially less when compared to the classical disease presentation, the severity of individual renal or cardiac manifestations in advanced stages of patients with late-onset variants may be significant enough to require renal replacement therapy or pacemaker/cardioverter defibrillator implantation.
Since SAM is essential for many cellular transmethylation reactions (e.g., epigenetic regulation) ( Strauss and Reyes-Dominguez, 2011 ), and SAH may be an inhibitor of cellular methyltransferases ( Burgos et al., 2012 ), there may be significant antifungal drug target potential associated with the overproduction of BmGT or inhibition of GliK activity- both of which may cause SAM dissipation.
Identification of a single potential pathogen in numbers as low as 200 cfu/mL may be significant, such as in acute urethral syndrome, but requests for culture results reports of <10 000 cfu/mL should be coordinated with the laboratory so that an appropriate volume of urine can be procesed.
Although the intakes of nutrients-of-concern were blunted due to the regulatory changes, they likely prevented a ‘High in’ nutrition symbol from inadvertently discouraging consumers from choosing products that may be significant contributors of nutrients-to-encourage.
10 In recent years, the development of DNA microarray technologies has revealed that submicroscopic deletions and duplications of DNA, known as copy number variants (CNVs), may be significant in autism susceptibility. 11 , 12 , 13 , 14 Recent surveys identified a higher rate of de novo CNVs in autism pedigrees compared to controls, with the increased rate becoming more exaggerated in singleton than in multiplex families. 10 , 12 , 13 Nevertheless, it remains difficult to interpret the significance of the numerous CNVs identified in ASDs, to distinguish those that influence susceptibility from normal polymorphic variation and to understand how they might interact with other genetic and non-genetic factors.