“may be significant”

Due to metabolic heterogeneity, there may be significant metabolic differences among patients.

We suggest that there may be significant overlap, and therefore functional redundancy, between two pore channel subtypes ( Tpcn1 and Tpcn2 ), allowing NAADP-dependent actions to persist.

There may be significant differences in clinical care, and the use of ICD9 codes, that is observed in different ethnicities, between different physicians, and across different healthcare providers.

On the other hand, advantages on prognosis may be significant, especially in pediatric epilepsy and tumor surgery.

Even as renal failure develops, the kidneys have the ability to compensate and there may be significant kidney fibrosis unaccompanied by measurable changes in GFR [ 14 ].

Our hypothesis is that in in BC patients, in addition to a high frequency of vitamin D deficiency, there may be significant correlations of vitamin D deficiency with osteoporosis parameters.

Curriculum content Curriculum content was another item for which compliance was quite low (37%), as we also found when surveying primary schools, but the potential for it to influence behaviour may be significant.

Also, a flat ST segment during exercise may be significant for coronary ischemia [31] ; • Atypical angina describes chest pain that may be related to cardiac causes but does not meet all 3 criteria in the NICE guidelines [23] .

The 2013 Australian Dietary Guidelines (ADG) review found suggestive evidence that vegetable consumption is associated with a reduced risk of weight gain 4 and the 2010 Dietary Guidelines for Americans found the association was modest, but may be significant in the long term. 5 These positions may reflect difficulties with food-based dietary trials. 6 , 7 Randomised controlled trials provide the appropriate basis for nutrition recommendations, 8 but for demonstrating long-term effects there are problematic issues.

Other invasion patterns, however, may be significant in some cases.

Even with high vaccine coverage, some adherence to other measures may be needed when the number of infections rises, because vaccine efficacy is less than 100%, especially against new variants of SARS-CoV-2 81 , and because the morbidity and longer-term health morbidity impacts of infection may be significant.

However, we note that the post hoc interpretation of PPI results can be ambiguous as significant increase in coupling from one region to another region may be significant when testing for a PPI in the opposite direction 52 .

In extremely stiff soils, w(r p )/w(0) may be significant, yet the differential settlement [w(0)−w(r p )] is small because of the small settlement magnitude.

On the other hand, there may be significant variability within this population due to differences in gender, age, and other factors.

Thus, we suggest that there may be significant environmental differences between Japanese and Korean subjects.

No reliable valid method was developed to assess patients’ dietary intake of folate; this may be significant, as flour in Jordan is fortified with iron and folic acid under the auspices of the Ministry of Health and the vast majority of Jordanians eat bread daily (Food Fortification Initiative, 2014) ( 44 ).

Given the complexity of the OmpR and Fur regulatory circuits, post-transcriptional regulatory networks (Hfq/sRNAs) may be significant and contribute to the fitness of Y. enterocolitica.

This indicates that there may be significant numbers of patients with records elsewhere that are not identified when relying on manual querying alone.

Because PROMPT is an elective, patient-oriented registry, there may be significant ascertainment bias.

Although such factors were not evaluated precisely according to previous studies, they may be significant causes of delayed neck metastasis [ 19 ].

The fistula may be significant or insignificant.

A single gene can only reflect its own expression status, while gene pairs can demonstrate their interactions and more comprehensively capture the complex biological changes during the occurrence and development of diseases; 2) enhancing the specificity of disease diagnosis: due to pleiotropy, single genes may be significant associated with multiple disease, limiting the diagnostic specificity.

Thus, its administration in the perioperative period may be significant ( 1 ).

Measurements of IgG-GS9 from two preparations showed only a slight difference in R H (0.1 nm), indicating that these measurements were quite robust and relatively small differences in R H may be significant.

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .