Due to the temporal frame provided for structural and functional alterations to proteins involved in excitation-contraction coupling, the impacts of multi-day NO 3 − consumption may be significant for NO bioavailability [ 60 ].
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It is known that there may be significant differences between different populations in the appearance of symptoms, so, for example, in the case of Chinese patients, the first symptoms typically occur at the age of 20–30 years ( 3 , 8 ).
Secondary inflammatory changes such as papules with irregular borders, nodules, cysts, pustules and abscesses are often seen, and scarring may be significant.
pyriformis as a model system can lead to new questions about host–symbiont interactions at the cellular level that may be significant for the initial, and still ongoing, evolution of eukaryotic cells.
This finding may be significant biologically, as it points to the possibility that the size and number of biomolecular condensates may be controlled rapidly by regulators that interact with a fraction of phase-separating monomers, whose total mass may be conserved.
Other lifestyle factors such as food sharing and community living may be significant drivers 20 , 53 .
Viruses may be significant drivers of bacterial diversity [ 60 , 61 ], and the fact that their communities are heavily populated on human body surfaces makes it difficult to discern their role.
While there have been no previous studies comparing TNF-α secretion in DF from patients with or without diabetes, we hypothesised that there may be significant differences in the secretion and/or response to TNF-α by DF derived from T2DM skin that may impact on wound healing.
Such dependence was typically ignored in previous works but may be significant at high irradiation doses, as we demonstrate with basic TTM calculations for ruthenium, palladium, and gold elemental metals.
Covariates with a significance level less than 0.25 were included in further analysis because these may be significant in two-way interactions.
While this isotopic effect appears small (but nonnegligible) for He, being comparable to the actual precision of typical mass spectrometers, the magnitude of Ne isotopic anomalies generated by DTF may be significant, representing up to ~11% of Ne isotope signals expected for a pure upper mantle source ( 20 Ne/ 22 Ne ~ 12.5).
Although the losses due to leaf rust in the currently cultivated wheat varieties have not been calculated, they may be significant under favourable conditions for disease development, particularly if infection occurs early in the crop season or if a susceptible variety is sown late ( Malaker and Reza 2011 ).
18 Studies have shown that there may be significant differences among ethnic groups with regard to pain perception. 21 In view of South Africa's ethnic diversity, it was necessary to interrogate the role of ethnicity in the pain reported in this study.
Consequently, there may be significant differences in the average noise power of the subcarriers received by the demodulated signal after equalization.
Consequently, the activation of the NLRP3 inflammasome may be significant for the upkeep of the intestinal epithelial barrier in ALD patients, preventing bacterial translocation in the gut postinfection, and improving the prognosis of sepsis patients.
In this context, we posit that any surface-exposed Brucella lipoprotein may be significant beyond in vitro assays and not one lipoprotein but rather a combination of them may contribute to the platelet activation elicited by B. abortus .
low temperatures 72 ), this step may be significant.
Assessment of Toxic and Immunostimulatory Effects following Administration of scAAV8 miR-31/5,8,9 and scAAV8 miR-31/5 to HBV Transgenic Mice Toxicity caused by overexpression of RNAi activators may be significant and is potentially lethal. 12 , 18 Several analyses were therefore carried out to exclude toxicity of scAAV8 miR-31/5,8,9 and scAAV8 miR-31/5.
Possible financial effects of the AC-based allocation may be significant, for which further studies would be warranted.
The HI value of cereals was > 1, indicating that there may be significant potential health risks associated with the consumption of cereals alone among the local residents in northern Ningxia.
This dataset was sampled over a 20+ year range and features long distances where a correction factor may be significant.
The lack of significant effect of the sickle cell trait upon the time it takes for a patient to become positive again may be significant in that respect.
Four tests may be significant at random at the 1% level.
While well-immunized IPV populations have controlled poliomyelitis and, for the most part poliovirus transmission, evidence of increased virus shedding in IPV-immunized older children following oral exposure to live virus may be significant in terms of potential enhancement of silent wild-type or VDPV circulation, particularly in geographic areas of low vaccine coverage.
Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .