“may be significant”

It is thought that this route may be significant in the spread of COVID‐19, with growing evidence showing that it played a role in well‐documented outbreaks: for example in the case of the Skagit Valley Chorale event for which Miller et al. 4 show that aerosol transmission has to be considered in order to account for the extensive resulting number of cases.

En bloc resection remains the real curative treatment of Schwannomas, ensuring unlimited freedom from disease, although causing functional impairment which may be significant.

For endangered species with self-incompatibility, all genetic variation in the population may be significant to the species’ survival, so it is necessary to fully understand the genetic diversity of the population.

It was notable that we found a large number of genes exhibiting changes in different directions and opposing mRNA and protein levels, thus suggesting that there may be significant changes in post-transcriptional regulation and post-translational modification in endometriosis.

According to our research, a pre-operative measurement of <3 mm for RBH may be significant for figuring out what amount of bone gain can be obtained but is not always indicative of implant failure.

The issue of BRAF inhibitors having some potency against CRAF is well recognized for clinically used compounds[ 2 ], and the observed activity of IPA3 may be significant if it proceeds either through BRAF or CRAF inhibition.

The data on the circular, single-stranded DNA TTV may be significant and harbinger of more studies in the future.

While the absence of positive affect may be significant in many of the North American contexts where this feature was added, there is insufficient evidence to suggest that it is appropriate to all contexts or, more importantly, a universally necessary component of maternal sensitivity.

54 Hence, it may be noted that the signals may not have fully recovered when using a TR of 1500 ms and T 2 saturation may be significant at a TE of 35 ms.

However, for communication-bound tasks, the demonstrated improvement of the cartesian mapping may be significant.

In spherical anisometropia, a minimum difference of 1.25 DS may be significant.[ 55 , 56 ] What are the treatment options?

Additional economic losses relate to livestock deaths, which, although poorly quantified, may be significant, with an estimated annual incidence of 5 deaths per 100000 cattle, costing US$12.3 million annually in Africa and Asia.

Errors of 50 μm may be significant, compared to commonly planned interproximal enamel reductions (IPR) of 100–500 μm per tooth [ 39 ].

This may be significant with respect to the methemoglobinemia as porcine erythrocytes use hepatically derived inosine as a substitute for glucose for glucose ( Watts et al. , 1979 ) and it has been shown, in vitro , that inosine is used to efficiently generate NADH for the enzymatic reduction of methemoglobin in pig erythrocytes ( Sartorelli et al. , 1996 ).

Our finding that at least 28% of patients undergoing echocardiography have an elevated TR jet velocity suggests that the burden of PH in a general medical intensive care unit population may be significant.

Although it is likely that stimulation of the sacral roots, (SNS), stimulation of the pudendal nerve, and stimulation of the tibial nerve (PTNS) all affect central components of the neural circuits controlling the bladder, there may be significant differences.

In addition to natural carbonate dissolution, the contribution of agricultural acid (i.e., HNO 3 ) to the equilibrium/supersaturated state of calcite dissolution may be significant due to the large agricultural NH 4 + inputs in the study area [ 28 ], which can accelerate the rate of dissolution from carbonate rocks, thereby improving the equilibrium/supersaturated state of calcite dissolution. 4.2.3.

In this context it may be significant that alteration in excitability seen in our study was restricted to MVC like SPN and did not extend to changes in CVC like neuronal activity, implying a functional, cell-type selectivity in the deficit, rather than a global phenotype.

The expression of Tcf4 may be significant in the pathomechanism of recurrent depressive disorder [ 97 ].

This finding may be significant given the recognized role of EVs in promoting tumor metastasis [ 74 ] and the current lack of effective pharmacological agents to limit their release [ 85 ].

Lateral diffusion and vesicle tumbling are not expected to influence the line shape because of the large size and low curvature of MLVs, 19 , 23 but if FBTA disrupts the lipid bilayer and promotes the formation of smaller vesicles and/or non-bilayer structures then contributions of these modes of motion may be significant.

Additionally, identifying factors affecting adherence in patients from different genders and cultural backgrounds may be significant to understanding follow-up patterns in patients with IIH, majority of whom are females.

We should say that while our fluorescence reverse titrations ( Table 2 ) do not reveal significant differences in the cooperativity of DNA binding by the SSBs, small differences, undetectable in this assay may be significant in vivo .

Prior research, although primarily non-UK based, has shown that medication costs may be significant barriers to medication adherence. 4 15 Congruent with these observations, 23.71% of participants reported not collecting a prescritpion and 16.80% of participants reported having deviated from their prescribed medication regime (eg, skipping doses or half-dosing) due to the associated per-prescribed item costs.

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .