By targeting appropriate patients with HF decompensation that are candidates for outpatient therapy, it appears that there may be significant cost-avoidance if they are managed as we have described in this case series.
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In the literature
While the fold differences over control may be significant, it is difficult to tell how biologically meaningful these differences are without access to the actual titer data.
However, the microbiomes of species clustered more separately when samples were separated by site and sampling time, suggesting that there may be significant temporal and spatial variability within the microbiome of fish (Additional file 1 : Fig.
Our patient experienced insomnia for many years before the onset of motor symptoms, which may be significant in further defining the phenotype of this disorder.
If that relationship starts to break down, there may be significant repercussions with respect to healthcare outcomes and patient compliance.
It is possible that other unrevealed genes may be significant contributors to the interconnection between CCs and oocytes and result in different effects on IVF outcomes.
Even within a short distance, genetic differentiation may be significant due to possible migration or ecological constraints [ 64 ].
These glycans, though not directly bound by influenza viruses, are a fundamental component in mucins and therefore may be significant for the virus interaction with the host environment. 4.
Metabolomic profiling of cerebrospinal fluid in an acute EAE model in rats showed distinct changes in metabolites between the onset and peak stages of disease, suggesting that there may be significant changes in cellular metabolism over the course of neuroinflammation [ 120 ].
Accuracy of recall depends among other things upon one’s cognitive abilities, questioning environment, and levels of stress which may be significant during an investigation [ 10 , 11 ].
62 , 63 The third mechanism of 19 F nucleus relaxation is based on contact interactions (Con) which may be significant in the case of transverse ( T 2 ) relaxation of fluoroorganic complexes of d-elements.
Given the phototoxic processes associated with bisretinoids, the increase in bisretinoid production may be significant to the disease process.
However, it may be significant that the correlation with the remaining quantities (T1-frequency and cell shape regularity) is much lower.
This coupled with the up-regulated activities of the IFN-γ/Stat1 pathway and the increase concentrations of TNF-α and IFN-γ may be significant as this suggests possible T cell exhaustion from constant exposure to tumor antigens or the absence of the HLA-A2 allele 44 45 46 47 .
Although further research carried out in more realistic driving conditions is required for accurate determination of the influence of a ringing phone on a driver, these study results suggest that this influence may be significant.
Gender differences may be significant factors influencing food choices and dietary patterns, leading to variations in trace element intake.
Reactor format is not explored substantially, but one result from Voloshin and Swartz [ 66 ] implies that the reactor surface area to volume ratio may be significant, while substantial difference is also seen between batch and CE–CF reactions.
Although the effect of ethnicity in HbA 1c seems small, it may be significant if HbA 1c is widely accepted and applied as a diagnostic tool in our population.
There may be significant differences in seat belt usage in different parts of the country; it will be difficult generalizing the findings from this study to the rest of the country.
A longitudinal miRNA gradient may be significant for regulating gene expression, as microarray expression data revealed that predicted targets for both miR-182 and miR-96 were enriched in the basal (proximal) BP at P0, where the miRNA levels are lower [ 13 ].
Damage in those areas may be significant with mortality of established trees, and failure of replanting.
There may be significant reduction in image quality if an image that is lossy compressed is compressed again in a lossy manner, especially with a different scheme.
Third, there may be significant differences between domestic and foreign studies in terms of patient populations, medical conditions, and other factors, leading to greater heterogeneity in the results.
There may be significant association between some clinical features and the severity of WMH although the results have been variable.
Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .