Multivariate survival analysis showed marginal significance for CIMP-H in rectal cancers after Bonferroni correction (hazard ratio (HR): 4.13, 95% confidence interval (CI): 1.27–13.46, P =0.019 in OS; HR: 2.90, 95% CI: 1.04–8.08, P =0.042 in DFS) ( Figure 1 and Table 3 ).
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Interestingly, these metabolites, together with sarcosine, which showed marginal significance in females, p = 0.019, comprise the mitochondrial arm of the choline degradation pathway, suggesting that mitochondrial disturbances may underlie unfavorable CAM‐CRF profiles.
In turn, in evaluating variations (Δ) summarized in Table 5 , although we found some marginal significance, the same biomarkers showed interesting results. the highest variation in MYO have been seen in participants with at least one R allele in ΔHELMET ( p = 0.019).
For the animal stimuli type, there was significantly higher brain activation in the congruent condition in the vlPFC, t (21) = 2.295, p = 0.032 (marginal significance after FDR corrected), the SupraMarginal gyrus (SMG), t (21) = 2.529, p = 0.019 (FDR corrected), and the angular gyrus, t (21) = 2.829, p = 0.010 (FDR corrected) compared with the baseline.
The alternative phylogeny, in which CARD domain duplication precedes the RIG-I/MDA5 gene duplication ( S8 Fig ), was rejected as a plausible explanation of our sequence data, with marginal significance (SH-test p = 0.02).
ACTR3_SEPEP.1_C4 was associated with the shared peptides, and it was lower in tumors compared with NATs with a marginal significance ( P = 0.02).
crop height, number of tillers and root length, produced a marginal significance between soil textures ( P =0.02, df: 3, 212, F value: 4.96, F critical: 2.64, single factor ANOVA), with clay loam soils having the greatest reduction to crop biomass ( P =0.02, df: 69, t.stat: 2.14, paired unequal variance post hoc T test).
As predicted, the presence of subtitles facilitates accent adaptation compared to exposure without subtitles: participants in the Concurrent and Delayed subtitle condition transcribed words more accurately during test than participants in the Absent condition without subtitles with marginal significance ( β ^ = 0.078 , z = 2.34, p < 0.02).
After adjusting for this, the chemotherapy regimen has an additional marginal significance ( P =0.02), with patients receiving anthracycline-based chemotherapy more likely to achieve a pCR than those receiving other regimens ( Table 2 ).
A total of 603 TT and 5 TC carriers were identified in the patient group, resulting in an association with marginal significance (P = 0.02), which does not survive the multiple test corrections.
sORFs in 3′UTRs reach marginal significance in some samples ( P = 0.02 for mouse brain and zebrafish).
[22] showed marginal significance of AMD with ΔCNP147 after adjusting for key SNPs such as rs1061170 and rs10737680 or rs2274700 (p = 0.02 and 0.044, respectively).
The permutation test confirmed the GLM finding in that both C1C62-M3M4 and C62-M3M4 regimens resulted in marginal significance, suggesting higher mean responses than C1-M3M4 (p = 0.02 and p = 0.05, respectively).
Haplotype analysis of the Hong Kong samples showed only marginal significance in disease association for haplotype TTAT formed by rs1143679, rs9888739, rs1143683 and rs1143678 ( P = 0.021).
Notably, the sex × TSD interaction for theta-ERS at Pz (congruent) and P4 (incongruent) approached marginal significance (Pz: p = 0.021; P4: p = 0.033), but post hoc tests confirmed no significant simple effects between sexes under pre-sleep or after-sleep conditions (all p > 0.05).
Only video duration reached marginal significance (β = 0.0003; P = 0.022) with negligible effect size.
The marginal significance in M. fascicularis was improved ( P = 0.0224) when an additional eight M. mulatta chromosomes were analyzed together.
Regarding overall sleep quality, sleep deprivation symptoms were more prevalent during the first week of the academic year (n=28; 7.3%) compared to summer vacation (n=27; 7.0%), but with marginal significance ( p =0.023).
The minor A allele of rs2228611 was associated with a lower risk of CAD ( p = 0.034); modest effect in the additive analysis but also marginal significance was found in the recessive model [OR additive = 0.404 (0.184, 0.884), p = 0.023 and OR recessive = 0.452 (0.213, 0.963), p = 0.040] after adjusting for confounders.
Although FAR showed marginal significance in the HER2 subtype (log-rank test, p =0.024), it did not show any significance in the luminal B-like or triple negative subtypes ( Figure 4 ).
Experiment 2: Diet, but not infection, affects egg protein content, and both bacterial infections are persistent Reducing dietary yeast by 75% significantly reduced egg protein content compared to the standard diet (marginal significance, P = 0.024); however, bacterial infection had no effect on egg protein content (Fig. 5 ; Table 4 ).
Only rs1419881 and rs10484569 showed marginal significance ( P = 0.024 and 0.035).
In addition, for rs2249825 and rs1800625 polymorphisms, there was marginal significance in allele distributions between the two groups ( P = 0.024 and 0.029, respectively), and after the Bonferroni correction, no significance was found.
The mean GRS in cases was higher in the cases than in the controls with a marginal significance (4.89 ± 0.11 vs 4.58 ± 0.08, p = 0.024).
Equivalent exploratory stepwise regression models using left CIMT and mean CIMT as dependent variables confirmed that no predictor met the entry criterion for left CIMT, and sex showed only marginal significance for mean CIMT ( p = 0.025), consistent with the weaker and non-significant anthropometric correlations observed for left CIMT in Table 3 .