On the basis of our genetic association data in the Han Chinese population, the SNP within an NFKB1 intron region (rs4648068) showed marginal significance.
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The marginal significance between the scores of the delayed visual learning test and the strength of the left hippocampus also supports this explanation.
Final models were selected using stepwise modeling, omitting covariates with marginal significance <0.05, starting with analysis specific fixed effects.
The age- and sex-adjusted model showed that participants who consumed dairy products seven or more times per week had a significantly lower risk of hypertriglyceridemia (HR, 0.81; 95% CI, 0.68-0.96) with marginal significance in the trend test.
No familial confounding was found for vegetables, while the results for fruit were inconclusive, likely due to smaller sample size and the marginal significance of the main result.
Max to min peaks comparison of non-paretic side showed marginal significance before and after HAL intervention for knee joint ( P -value np-pre Vs np-post: 0.03, OP: 33.3%) and significant difference when comparing patients before and after HAL intervention against healthy volunteers ( P -value np-pre Vs healthy: <0.01, OP: 99.8%; np-post Vs healthy: <0.01, OP: 93.4%).
It should also be noted that in addition to left pSTS, we also found more activation in left IFG triangularis, albeit with marginal significance, for reading disconnected words than characters.
The reason for the significantly inferior survival of those randomised to maintenance therapy is therefore unclear. Given the small numbers of patients accrued to this study, the absence of a clear explanation for the inferior survival of the maintenance group and the marginal significance of the difference, it is probably wisest to interpret the data as showing no benefit for maintenance chemotherapy.
Increasing trends in butyrate-producing genes were also observed following LF treatment, although these changes reached only marginal significance ( Fig. 7 ).
There is some overlap between CSF total tau between these two groups and only marginal significance when assessed in the context of multiple comparisons, and so because of the small sample size of this study, it is not currently possible to assess the generalizability of these findings.
A comparable increase was not evident in the 2-Back conditions (List B to C: p = 0.35; List C to D: p = 0.07), although this latter contrast does reach marginal significance.
However, a multivariate Cox model that included other clinical factors found that only a high abundance of Peptidiphaga retained marginal significance for improved RFS (Fig. 4 E, additional file 4: Table S3 and additional file 5: Table S4).
Also, gender-related volumetric difference was not stated in our study due to a limited number of samples, which showed nil or marginal significance.
Thus, the first genome-wide association study (GWAS) reports a trend for HLA-C*04:01 association to the disease severity in the Italian population with a marginal significance, and a significantly lower number of HLA class I bound SARS‐CoV‐2 peptides in the most severe group of the Italian and Spanish patients ( 35 ).
When compared with the GG/AG genotypes, the AA genotype was found to had a marginal significance to increase renal cancer risk ( Hirata et al., 2009 ).
Within the groups, there was also generally no difference in the reproductive output of pairs from within‐line versus between‐line crosses; the only exception was in group D where one within‐line cross showed higher reproductive output than the between line hybrid cross, with marginal significance (Table 5 ; Figure 4B ).
( Table 1 ) The APCs showed the following trends: For the overall population, the AAMR decreased non-significantly from 1999 to 2014 (APC = -0.22, 95% CI: -0.61 to 0.18), increased with marginal significance from 2014 to 2018 (APC = 4.26, 95% CI: 0.00 to 8.69), and remained stable from 2018 to 2023 (APC = 0.15, 95% CI: -1.56 to 1.88).
Though that study provided novel insights into the biology underlying BCC, the false discovery rates of the identified pathways are of only marginal significance.
Multiple comparisons for the reward variant using Tukey's Honestly Significant Difference test showed that only the unidirectional instructions for seeking reward differed from the standard and no hint instructions; however, the significance levels of these variables were p = 0.08 and p = 0.09, respectively, indicating marginal significance.
Regarding EST-EXP, the estimated coefficient (β=-0.129, p=.087) approached the threshold of statistical significance, indicating marginal significance (Olsson-Collentine et al. , 2019 ), pointing to a possible slight decrease.
Moreover, marginal significance was assumed when p-values ranged from 0.05 to 0.10.
Further, their anxiety levels also tended to be lower following OXT treatment, although with marginal significance (unpaired t test for VPA + OXT vs.
Additionally, there was a marginal significance in the relationship between H. pylori infection and sex (male), lower maternal age, household density and lower familial income.
The sugar alcohol threitol and the essential amino acid threonine (marginal significance) were also reduced upon atenolol treatment in the combined dataset.
Rs854571 was associated with hemorrhagic stroke, with marginal significance ( P unadjusted = 0.0500, OR = 0.76 [95% CI = 0.57-1.00]) using the additive model, and rs705381 showed a significant association in both additive ( P adjusted = 0.0290, OR = 0.62 [95% CI = 0.40-0.95]) and dominant models ( P adjusted = 0.0165, OR = 0.57 [95% CI = 0.36-0.90]) (Table 4 ).