“marginal significance”

Calcium-phosphate metabolic profile The frequencies of calcium-phosphate metabolism-associated events were similar between the ALN/D5600 treatment group and calcitriol treatment group, except for hypercalciuria at 6 months, with a marginal significance (9.4% vs. 18.5%, P = 0.05) (Table 2 ).

After eliminating associations with a P‐HEIDI value less than 0.01, a total of 4,880 CpG sites around 285 distinct genes met the criteria for marginal significance ( p < 0.05), as shown in Table S3 .

4 b, we inferred a list of 16 candidate master regulator (“MR”) TFs: ATF3, CEBPB, CEBPD, EHF, ELK3, FOSL2, FOXO3, HOXA7, IRF4, IRF8, JARID2, RARG, TCF7L2, THRB, ZEB2 and ZNF217 that either: (a) are significantly differentially expressed between bulk cDC1 and cDC2 (BH p.adj < 0.05, absolute value of log2 fold change > 1, Additional file 2 : Table S5); or (b) regulate the differentially expressed genes and exhibit differential expression between bulk cDC1 and cDC2 with marginal significance ( p -value < 0.05, absolute value of log2 fold change > 1, Additional file 2 : Table S5).

The genetic effects of the six loci were further evaluated on the GC risk according to the confirmed histological type (intestinal and diffuse type), and the GA genotype of rs17037102 in DKK2 was found in association with an increased risk of diffuse GC with only marginal significance (adjusted OR = 1.77, 95 % CI: 1.01-3.11, P = 0.05).

Although the difference reached marginal significance ( P = 0.05), it remained far below the minimal clinically important difference, indicating no clinically meaningful difference between the techniques ( FIGURE 3 ).

Among them, the responder group exhibited increased activation of the pathways regarding interleukin signaling ( figure 4A ) and ERBB2/3 ( figure 4B ) with marginal significance (p=0.05 and p=0.493, respectively).

The difference in TG showed marginal significance (4.18 in boys and 4.30 in girls, p = 0.05); the other MetS components (BMI, FBG, and HDL-C) did not differ by gender.

Another retrospective study including 441 NAFLD cases and 441 propensity score-matched controls demonstrated that NAFLD independently increased the risk of overall CRN occurrence with marginal significance (adjusted HR, 1.31; 95% CI, 1.01 to 1.71; p = 0.05) [ 35 ].

Because results using the summary score model with the validation cohort showed evidence of lack of fit at marginal significance ( P = 0.05), and because the AUC (0.65) was worse than it was using the standard model, we did not pursue the summary score with the merged cohort.

Contact with goats showed the strongest association with TB (OR=2.81, 95% CI: 0.78–9.37, p = 0.089), which reached marginal significance after adjustment for age and sex (aOR=3.03, 95% CI: 1.00–9.17, p = 0.050).

Apart from the acceptance rate (80.8%) among the group aged 25–34 years, those aged between 55–64 showed more willingness to be vaccinated compared to their lower age group with marginal significance ( p < .05), and the acceptance rate was 90.0%.

A threshold for marginal significance we assume p < 0.05, and for high significance p < 0.01.

When comparing outcomes by IMS regimens, there were no significant differences in preterm births ( p = 0.60) between groups; however, marginal significance was observed for live births ( p = 0.05) ( Table S1B and Fig.

Regarding the CES-D, which is the primary outcome measure, the intervention effects estimated by the mixed-effects model analysis at T1 (postintervention) were not significant, although the CES-D score at T1 of the iCBT arm was lower with marginal significance as compared with that at T1 of the waiting list arm (−1.28, 95% CI: −2.58 to 0.02, p = 0.05).

Mean glucose concentration within the first hour (Glu 0–1 h ) of PD fluid exchange was found to be higher in the high HbA1c group with marginal significance ( P = 0.05, Table 4 ).

NBRM The NBRM applied to the regions of the European part of the RF (Zone 1 at Figure 1 ) identified the following significant factors associated with the intensity of ASF outbreaks among wild boars: the proportion of forest cover, the number of ASF outbreaks in domestic pigs, and the density of the wild boar population (the latter with a marginal significance level of p =0.05) ( Table 2 ).

In addition, outcomes related to gait balance and symmetry displayed marginal significance, with subgroup z -values of 2.00 ( P = 0.05) for gait balance general, 1.94 ( P = 0.05) for gait balance timing, and CIs for the MD overlapping zero.

This analysis reveals that the primary factors influencing bone density along the growth plate are thickness (p = 0.03) and the number of oscillations, which shows marginal significance (p = 0.05).

The association between percent of total energy from sugar and body fat percent at follow-up had marginal significance ( p = 0.05).

In the motivated effort model, only the group effect that had already being observed across all load conditions achieved marginal significance ( b = -3.02, t = -1.97, p = 0.05, n = 54), but no effect of maximum digit span ( b = -0.48, t = -0.90, p = 0.37, n = 54) or motivated effort ( b = 0.04, t = 0.20, p = 0.84, n = 54) was found.

Changes in the percent of positive opioid tests also varied by indication group attaining marginal significance (phase × group: F [2,39] = 3.2, p = .05).

Results from experiment were considered significant at P < 0.05 and a marginal significance between P > 0.05 and P ≤ 0.10.

However, years of experience showed marginal significance ( F( 3, 146) = 2.669, p = 0.050, η2 = 0.052), indicating a small effect, with nurses having more experience reporting more favorable attitudes, as shown in Table 6 .

A tendency for ACPA + /RF + RA patients to be younger achieved marginal significance (P = 0.05).

The Opiate drug category was the only non-marijuana drug type to reach marginal significance: left anterior insula–cerebellum ( p < 0.05 uncorrected).