“marginal significance”

In addition, multiple terms with marginal significance were detected with the full GO but not NIGO due to the stochastic nature of GSEA (e.g. 'proteolysis', 'cytoplasm', 'caspase activation' and 'metal ion binding').

A negative correlation was found between tumor functionality and AUC (Spearman correlation coefficient= -0.481, P=0.051) with marginal significance, in line with above findings, indicating a tendency that tumors with active hormonal function might respond better to mitotane treatment.

These genes are associated with completely different molecular functions and pathways while their independent predictive potential is small with univariate statistical analysis showing marginal significance or no significant changes between responders and nonresponders ( Fig. 3D ).

Finally, rs1981867 located on chromosome 16q23.2 showed satisfactory statistical significance in Stage I ( p value 3.7 × 10 −4 ) and in joint analysis ( p value 4.32 × 10 −4 , FDR 2.16 × 10 −3 ) but showed only marginal significance in Stage II ( p value 0.03).

Among other families, only one clade of str genes had a marginal significance (set N).

Sex differences did not reach statistical significance in maze A, B and C, but showed a marginal significance in maze S and R, where males performed better than females across trips.

Confidence intervals for age adherence rates (OR: 1.4, 95% CI: 0.9–2.1) suggest precision despite marginal significance.

reported that this SNP was associated with hepatocellular carcinoma susceptibility with marginal significance [ 12 ].

Notably, in the liver single-tissue analysis, a single gene ACPP approached marginal significance ( P liver-tissue = 4.76 × 10 −6 ; Figure 1A and Supplementary Table 1 ).

Pooled results found that β-agonists were associated with a two-fold increased risk for total mortality compared with corticosteroids, with marginal significance.

It is concluded that the day-night rhythm, and thus SCN itself, may have only marginal significance in glycogen metabolism regulation [ 19 ].

However, this finding only revealed a very marginal significance.

Second, we observed a marginal significance on sex difference between two groups in the current study.

“in 1 day” (b = − 0.069, p = 0.067) and “right now” vs.”in 1 month” (b = − 0.071, p = 0.056), showed marginal significance.

Result: A statistically significant difference was found across different smoking indices for computerized spirometer parameters forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), marginal significance for peak expiratory flow, and no statistically significant for FEV1/FVC ratio and forced expiratory flow between 25 and 75% of vital capacity.

Nonetheless, BGLMMs led to conclude to very strong marginal significance of the three effects.

The significance level at 0.05 and the marginal significance level was set at 0.10. 5.

Significance or marginal significance (for the same effect) on 3 consecutive bins was taken as evidence for the existence of a certain effect.

Conversely, lower Pb levels (< 4.5 μg/g) were associated with ASD (OR = 0.164, 95 % CI: 0.0215–0.980; p = 0.0569), although this result approached marginal significance.

However, this finding should be interpreted with caution given the marginal significance and exploratory nature of subgroup analyses.

No difference in the MNC dose was noted among 3 groups, yet an association between the CD34+ cell dose and the different groups was found, although with a marginal significance ( Table 1 ).

In this study, it was shown that the extension of fastbayes to include a marginal significance test for SNP effects, which is theoretically founded, enables the detection of loci relevant to genetic variation.

The lower significance of p < 0.10 indicated the marginal significance of the studied interaction.

Most of the methods focus on testing marginal significance of the associations between pathways and clinical phenotypes.

Nevertheless, our data showed a concordant trend in response to RT and a better DFS approaching a marginal significance, leading to the possibility of using alternative RT regimens or combining RT with systemic drugs such as immune checkpoint inhibitors, to further improve the objective response rate of neoadjuvant therapy and postoperative long-term survival outcomes in patients with early-stage HCC.