“marginal significance”

Although no group differed significantly in the adjusted regression models, a marginal significance was observed among seventh-grade boys.

We then used 123 unique compound-disease pairs with marginal significance (FDR < 0.1).

Multivariable analysis indicated that the original HFTPs of 2 and 3 and the revised HFTPs of ≥2 were independently associated with the occurrence of primary outcome events after discharge, in addition to anemia and impaired renal function, while one point was related with marginal significance in the multivariable models in both scores ( Table 2 ). 4.

However, after adjustment for known metabolic risk factors, multivariate regression analysis showed that this association was attenuated (OR: 1.17, 95% CI: 0.95–1.43) with marginal significance.

major homozygotes showed a similar effect of lower odds in the latter to be present, which was however reaching only a statistical tendency or marginal significance depending on the adjustments ( Table 3 ).

Association of genetic variants with serum uric acid levels and diabetes risk No significant association was observed between the GRS and potential confounders of diabetes except for smoking status ( P =0.02) with marginal significance ( online supplementary table 6 ).

All tests of hypotheses were two-tailed and conducted at a significance level of 0.05 and at a marginal significance level of 0.15.

However, as shown in Table 2 , the main cohort difference (β) is negative with only marginal significance in 2007 but turns positive with strong significance and larger effect sizes in both 2012 and 2018.

Therefore, the primary and secondary endpoints were opposite in these two trials. When these two trials were combined and an integrated analysis was performed, probucol was demonstrated to reduce cerebrocardiovascular events in patients with CAD, with marginal significance.

The DLL4 density in HM was also higher than in the LM and NM groups, despite the former comparison showing only marginal significance because of small sample volumes.

Basically, variables that achieved statistical significance and marginal significance on univariate analysis were entered into multivariate analysis by the Cox proportional hazards model to identify significant independent predictive factors.

Notably, although similar distributions between phylogenetically related subspecies were observed for SNP8, this SNP was not a significant predictor of the dummy-coded genetic lineage, probably due to the marginal significance of differences between samples of the ssp.

There is no clear interpretation of the three-way interaction term and, given its small effect size and marginal significance, it is unlikely to be of importance.

However, this and the effects for obsessive passion remain inconclusive due to marginal significance and therefore suggest further research.

Differential expression statistics were used to define a gene weight vector u j (of size equal to the total number of genes in the considered analysis) for each cell type j combining the log fold change x ij of each gene i with its adjusted p -value (Benjamini-Hochberg method [ 69 ]); to reduce noise, scores associated with marginal significance were set to zero, that is y i j = − log 2 ( x i j ) log 1 0 ( p i j ) when p ij < 0.05 and log 2 ( x ij ) ≥ 0.5, while y ij = 0 otherwise.

Patients (neoadjuvant-treated CRC liver metastasis from a phase 2 clinical trial) overexpressing CXCR7 displayed marginal significance with worse median PFS.

This was particularly the case in the PSYNDEX database for literature from German-speaking countries, even though this association only reached marginal significance.

The high proportion of branch neoantigens was associated with short overall survival in a marginal significance, which was probably due to the insufficient sample size (Fig. 7d ).

A borderline inverse association was also observed for birth weight (β = −63.82 g; 95% CI: −128.87 to 1.23; p = 0.05), though the small effect size and marginal significance require cautious interpretation.

Results (moderate positive with marginal significance) indicated a probability to integrate road length into a new variable in order to enhance the expression of the spatial distribution of light.

This finding deserves further exploration as it suggests, but (because of the marginal significance and cross-sectional nature of the data) cannot prove the existence of a hypothetical window of opportunity to prevent seroconversion among SCY, primarily by providing early avenues to exiting the street.

Older age (≥60 years) was not associated with major bleeding in our study though a previous analysis of the NIS database, which focused on the impact of age on the delays in initiation of TPE for iTTP, reported marginal significance of age ≥ 60 years as a risk factor on major bleeding [ 22 ].

Compared to previous studies, our research had an overall short follow-up period and a relatively small sample size, which may result in decreased statistical power, marginal significance for demographic factors, and weaker inference in conclusions.

The PAN dummy is statistically insignificant, while POST shows only marginal significance, suggesting that temporal effects, once structural determinants are controlled for, do not systematically alter the DRG-based complexity of hospital activity.

However, secondary and exploratory outcomes should be interpreted with caution given the absence of adjustment for multiple comparisons, and findings with marginal significance may represent chance findings.