We have also identified a statistically significant association between positivity for c-erbB-2 and female sex, undifferentiated histological-grade tumours, intestinal histological type, and presence of nodal metastases, showing an interesting correlation with the presence of more than 6 nodes metastatic ( P = 0.052) although with a marginal significance.
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“marginal significance”
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p=0.07
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However, its impact on Cz and frontal electrodes TBR showed only marginal significance ( Table 2 ).
Moreover, studies in humans have revealed SNP that were related to myocardial infarction with a marginal significance [ 32 ], which was, however, not confirmed by other studies in humans [ 33 ].
In this model, only sample was a significant predictor for the RMET Score, while the interaction effect only reached marginal significance.
Additionally, the quadratic term X 1 2 and interaction term X 1 X 2 were included due to their marginal significance (F-values of 4.53 and 4.46, p-values of 0.0529 and 0.0547, respectively), reflecting their potential impact on the model.
Specifically, AU05_r (Upper Lid Raiser) reached statistical significance ( p =.03), while AU20_r (Lip Stretcher), AU01_c (Inner Brow Raiser), AU20_c (Lip Stretcher), AU23_c (Lip Tightener), and AU26_c (Jaw Drop) showed marginal significance ( p -values ranging from 0.045 to 0.077).
First, multiple testing in our regression analyses would increase the likelihood of chance findings, especially for those results with marginal significance.
There was a marginal significance for an increase of the area under the curve until the last measurable concentration (AUClast) of sorafenib in the presence of vinorelbine.
The association signals for all three SNPs were characterized by low FDR values (0.023–0.054); the 1000-times permutation tests also showed marginal significance for rs13250873.
The marginal significance revealed by this logistic regression, coupled with the high significance revealed by the repeated measures ANOVA, indicate that our results are largely robust to statistical approach and, moreover, are consistent with a statistically significant line by age interaction effect.
Specifically, although they showed a marginal significance in the attending to behavior, they did report significantly more commenting-reposting and talking about behaviors as compared with suicide ideators.
Serum AFP level was the strongest adverse predictor for OS but only had marginal significance in terms of RFS.
If an epistatic term is included in the model, we retain the main effect terms, regardless of their marginal significance, to ensure that the model is interpretable.
The interaction between household net-income and major medical diseases showed a trend with marginal significance in the fully adjusted model (Odds Ratio (OR) 0.78, 0.60–1.02): Major medical disease only increased the risk in persons in the low household net-income category (< 3000 €) and not in the group of persons with high income (Fig. 1 ).
The result showed that the annual risk of re-bleeding was 2.7% in surgical group, and was significantly lower than that in non-surgical group (7.6%/year, p =0.042), although the result represented marginal significance [ 28 ].
Neutrophil recovery within 30 days post-HCT ( P = 0.095) and autologous HCT before allo-HCT ( P = 0.051) had marginal significance and were included in multivariate analysis.
This might sort out the issue of “marginal significance” where the author attempts to ensure some factors appear significant, yet they are not.
TP showed marginal significance in the models, possibly reflecting indirect effects of nutritional–inflammatory status on immune function, although its effect size was small and clinical interpretation should be approached with caution.
While the marginal significance of older age as a risk factor should indeed be interpreted with caution, we believe that describing these findings contributes valuable insights to the limited body of literature.
However, miR-126 exhibited a significantly different expression pattern in OS, albeit with marginal significance.
Results with marginal significance are interpreted with particular caution.
Supplementary Tables S5A–E contain the distribution of posterior probabilities (PPs) corresponding to these 5 genomic regions and Supplementary Tables S6A–E contain the marginal significance estimates for each annotation, overall likelihood ratio test (LRT) estimate and corresponding P-value contributing to posterior probabilities of SNPs within the 5 regions.
The variants TNF-α-308G/A, 5-HTTLPR, 5-HTTVNTR, and APOE showed marginal significance for OR G (95% confidence interval [CI]): 2.01(1.31–3.07); 1.31(1.09–1.58); 1.85(1.16–2.95); 1.79(1.10–2.92); and 1.79(1.10–2.92) respectively.
3D ), although only a marginal significance is achieved due to the reduced number of samples in each case.
The marginal significance of anthropometric predictors underscores the need for larger, longitudinal studies to further clarify their role.