“likely to be significant”

In particular, and in line with the GRADE-CERQual approach, when making our assessments on relevance, we evaluated whether there are likely to be significant differences between preterm and LBW infants and infants that are not preterm and LBW that would reduce our confidence in relation to each review finding.

In our dataset - in which 96 hits were derived from a screen of 10,000 protocols - a triple hit from the same protocol would occur randomly once in every thousand repetitions of the experiment and therefore its occurrence in our screen is likely to be significant (i.e. indicate a highly effective protocol).

In summary, while exogenous and endogenous cueing may engage some shared mechanisms, there are also likely to be significant differences.

While the placenta undoubtedly makes an important contribution to the plasma CX3CL1 concentration, synthesis of this chemokine by maternal blood mononuclear cells and other tissues is also likely to be significant, although the exact extent remains uncertain.

Consequently, their contribution to the massive burden of LBP ( Vos et al., 2016 ) is likely to be significant.

Caterpillars of two lycaenid butterflies, Chlorostrymon maesites (Herrich-Schäffer, 1865) and Cyclargus thomasi (Clench, 1941), consume immature seeds of Cardiospermum corindum in southern Florida, and because they cause considerable (occasionally more than 50%) loss in production, they are likely to be significant interspecific competitors of Jadera haematoloma ( Carroll 1988 ).

However, this increase did represent a large relative increase (304.00%) in methylation, suggesting that it is likely to be significant from a biological standpoint.

21 The introduction of additional potent steric zipper motifs by the disease-causing mutations in a PrLD is likely to be significant for two reasons.

In fact, there are likely to be significant trade-offs, contestations, conflicts and unforeseen side effects and consequences of urban sustainability initiatives at all scales.

Conclusions African elephants have disappeared from many of their range states [54] , and there are likely to be significant conservation and ecological benefits from restoring flagship species to areas they cannot recolonise naturally [61] .

Since costs for registration, transportation, storage, procurement, and administration are likely to be significant; we took some of the cost components of the Malawi input subsidy program from Chirwa and Dorward (2013) to provide a proxy for what the costs of Nigeria’s subsidy program could be. 13 Table 10 provides benefit–cost ratios of the GES, valued at market prices and without accounting for economy-wide effects.

Importantly, not all impacts are financial; psychological stress and public trust erosion are likely to be significant, though considerably more difficult to quantify.

We also predicted that the social capital indicators, neighborhood participation and telephone interaction, would be less likely to be significant with increasing age.

Moreover, if we take into account that there is abundant vegetation and water present (river banks, parks and irrigated croplands) and high humidity, factors that promote the proliferation of mosquito vectors, in those areas where positive dogs have been detected, the risk of CVBD infection and its effect on public and animal health is likely to be significant throughout the year.

When classification systems exhibit low reliability and validity there is likely to be significant heterogeneity within each category of the classification and thus a resultant variability in the treatment of injuries between clinicians, between treatment centers and across various geographies.

In addition to Peters anomaly, corneal invasion by lens epithelium, lens capsule deposition in the corneal stroma, as well as increased keratocyte density are together likely to be significant contributors to corneal opacity.

Additionally, there is likely to be significant heterogeneity in SES within postcodes and future studies should consider accounting for such heterogeneity by collecting SES data on an individual case level.

24 The exact mechanisms causing this vasodilation are not fully understood but evidence indicates that neither the direct vasodilatory effects of amino acids on the blood vessels, nor their metabolism in the liver or the release of hormonal factors from the liver, are likely to be significant contributors.

We speculate that in more arousing situations (e.g., those that are stressful), the child may activate regulatory processes learned during shared moments with the father, making links more likely to be significant.

There are likely to be significant flow-on effects of a safer night time environment for tourism and investment. 5.

For the Unwanted group, only guilt, depression and grief were significantly greater than relief, though many of the other negative reactions approached significance and appear likely to be significant with a larger sample size.

The differentially expressed genes detected by both experiments, and therefore highly likely to be significant for the VBNC state, were of particular interest.

Nevertheless, the neuropsychiatric burden of this pandemic is currently unknown, but likely to be significant.

Therefore, we do not think these are likely to be significant confounds in our findings.

The results that are found in an integrative analysis are more likely to be significant than the results of one single experimental technique as discussed in Steinfath et al.