Also brain tumors and/or sarcomas were overrepresented in the carrier families (28.6%, Table 2 ); the difference being highly significant when compared to the incidence of these cancers in the analyzed cohorts (5.1%, P = 0.0007, OR 7.4 95% CI 2.7–19.9).
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Although the interaction between baseline Ct and number of high Ct samples in the pool was not very strong ( P =0.014), the interaction between baseline Ct and number of low Ct samples in the pool was highly significant ( P =0.0007), as shown in Figure 2 .
There was a highly significant correlation between HPyV6 DNA PCR and HPyV6 FISH results ( p = 0.0007; Fisher’s exact test).
This strategy led to a highly significant 3‐fold decrease in gonocyte viability compared to equivalent populations of untreated cells ( P = .0007) (Figure 7A ).
When patients were dichotomized by averaged expression values of SPARC and SPP1 , the association between the two genes and OS was highly significant (P = 0.0007, by log-rank test), strongly suggesting that the prognostic association of the two genes in EAC is synergistic ( Figure 4C ).
This difference was highly significant ( P = 0.0007).
For 85 ccRCC patients treated with Sunitinib in the IMmotion 150 cohort, the DKC1-high group exhibited significantly increased TERC expression (high vs low, P = 0.014); however, a highly significant increase was seen in female ( P = 0.0007) but not male ( P = 0.18) patients (Fig. 5 B).
The FAS test for letter fluency was most highly significant with a p < 0.0007.
A highly significant association between allele imbalance on 17p and 17q in this material has been observed previously (Fisher's exact test, P = 0.0007; data not presented).
Normo-weighted subjects showed a highly significant decrease in periodontal inflammation (PISA index) (986.99 mm 2 ± 591.47 vs. 477.28 mm 2 ± 542.55, p = 0.0007) after periodontal treatment, shifting from a severe state of periodontitis to a mild state of periodontitis ( Figure 3 ).
Quantitative analyses confirmed that the Mrp2 immunogold labelling density in Wortmannin-inhibited samples remained as high as in controls despite insulin stimulation, while insulin also in the new media conditions with DMSO still led to a highly significant ( P = 0.0007 vs. control and P < 0.0001 vs. insulin + Wortmannin-treated cells) decline of Mrp2 levels at the plasma membrane (Fig. 5 h).
The difference between the groups was highly significant (p < 0.0007).
Pairwise comparisons showed a highly significant increase in similarity in PK pairs (PK: paired: M = 0.03, SD = 0.04; shuffled: M = −0.01, SD = 0.02; t (18) = 4.1, P = 0.0007, CI: [0.018–0.058], Cohen’s d = 0.94).
If the number of pregnancies are grouped so that three or more pregnancies are placed in the same category, as in most previous studies (Byers et al., 1982; McMichael & Potter, 1984; Potter & McMichael, 1983; Weiss et al., 1981), there is a highly significant protective trend with increasing numbers of pregnancies (P = 0.0007) (Table II).
For the multi-rate stimulus ([1234]; compare filled orange triangles), all participants, with the exception of MED06 and possibly MED05, assigned higher pitch ranks to the LD than to the SD version, and this difference was highly significant at the group level ( t (7) = 5.79, p = 0.0007**, d = 2.0).
The interaction between AgNO 3 concentration and temperature (AD) was highly significant ( p = 0.0007, F = 16.35), suggesting a strong combined effect on ZP.
The survival analysis showed a statistically highly significant difference in all three key oncologic indicators OS, OS-PO, and PFS-PO (p=0.0007; p=0.0002; p<0.0001).
Mice receiving iNO showed a modest but reproducible and highly significant enhancement in survival (p = 0.0007; Figure 1A ) compared to control mice breathing air alone.
The test for subgroup differences was highly significant (Q = 19.26, df = 4, p = 0.0007), confirming differential efficacy by concentration. 3.8.
For TPC, the quadratic model was highly significant (F = 32.20, p = 0.0007; Table 2 ), indicating that the model adequately describes the relationship between extraction variables and phenolic recovery.
A similar pattern was observed for SMS, SMOX and SRM, all of which were associated with poor prognosis in LIHC, while the others did not show any highly significant difference (SMS; HR 1.9, p = 7e−04; SMOX: HR 1.7, p = 0.003; SRM: HR 1.7, p = 0.03).
Moreover, we found a highly significant positive correlation of the network gamma oscillations (power×duration) with the SWR-area increase (R = 0.58, n = 30, p=0.0007) and no correlation with the SWR incidence (R = −0.28, n = 30, p=0.14).
Rs1017 was highly significant in a log additive model, with an 81% increase in risk associated with each additional copy of the T allele (OR = 1.81, 95% CI 1.29–2.54, P = 0.0007).
The number of ROI-ROI combinations detected in the actual data (53/504 tests) is highly significant ( P < .0007) and shown as a vertical dashed line for reference.
The difference between median values was highly significant ( p = 0.0007; Figure 4 ).