“highly significant”

This difference was highly significant (p = 0.0007), which indicated that the time that was necessary for bone healing was significantly increased (p = 0.0008).

Results There was a highly significant positive correlation between the two sets of antibodies ( r s = 0.621; P = 0.0007).

There was a highly significant correlation between HPyV6 DNA PCR and HPyV6 FISH results ( p = 0.0007; Fisher’s exact test).

At 10 ng/ml FGF8, the difference in proliferation between both cell lines was highly significant (P = .0007).

This increase in seropositivity with age was highly significant (logistic regression p = 0.0007).

When patients were dichotomized by averaged expression values of SPARC and SPP1 , the association between the two genes and OS was highly significant (P = 0.0007, by log-rank test), strongly suggesting that the prognostic association of the two genes in EAC is synergistic ( Figure 4C ).

From BSL to WK16, differences in changes were highly significant between Gr.Suppl.5 and Gr.Suppl.0 (18.3 vs 7.7 nmol/L, t test: p = 0.0007) and between Gr.Suppl.10 and Gr.Suppl.0 (23.5 vs 7.7 nmol/L, t test: p = 0.000001).

s'l'+l'l' ), a highly significant genotype effect was also observed (F 1, 155 = 11.9, p = 0.0007).

When applying the CV mortality results in univariate Cox regressions, we observed a highly significant risk reduction resulting from supplementing the participants with selenium and coenzyme Q10 for four years, also after 12 years (HR:0.58; 95%CI: 0.42–0.79; P<0.0007).

Post hoc t tests (with Tukey correction for multiple comparisons) revealed that TTX increases in activity were highly significant in both WT (p=0.0007) and TKO (p<0.0001) slices and that TTX produced a significantly stronger increase in the TKO (p<0.0001), while the baseline activity of cells from slices derived from the TKO and WT do not differ significantly (p=0.92).

For the multi-rate stimulus ([1234]; compare filled orange triangles), all participants, with the exception of MED06 and possibly MED05, assigned higher pitch ranks to the LD than to the SD version, and this difference was highly significant at the group level ( t (7) = 5.79, p = 0.0007**, d = 2.0).

Pairwise comparisons showed a highly significant increase in similarity in PK pairs (PK: paired: M = 0.03, SD = 0.04; shuffled: M = −0.01, SD = 0.02; t (18) = 4.1, P = 0.0007, CI: [0.018–0.058], Cohen’s d = 0.94).

Quantitative analyses confirmed that the Mrp2 immunogold labelling density in Wortmannin-inhibited samples remained as high as in controls despite insulin stimulation, while insulin also in the new media conditions with DMSO still led to a highly significant ( P = 0.0007 vs. control and P < 0.0001 vs. insulin + Wortmannin-treated cells) decline of Mrp2 levels at the plasma membrane (Fig. 5 h).

Also, the preoperative C1-INH concentration had a highly significant effect on time to recurrence of cancer (P = 0.0007), adjusting for age and disease extent.

In contrast, En1-Cre; Srd5a3 fl/- mice showed a severe and highly significant (p=0.0007) motor coordination defect assessed with the rotarod test ( Figure 1G ).

Although the interaction between baseline Ct and number of high Ct samples in the pool was not very strong ( P =0.014), the interaction between baseline Ct and number of low Ct samples in the pool was highly significant ( P =0.0007), as shown in Figure 2 .

For 85 ccRCC patients treated with Sunitinib in the IMmotion 150 cohort, the DKC1-high group exhibited significantly increased TERC expression (high vs low, P = 0.014); however, a highly significant increase was seen in female ( P = 0.0007) but not male ( P = 0.18) patients (Fig. 5 B).

Although this was still a highly significant reduction of melanoma cell numbers ( p = 0.0007), the surviving cell fraction increased again after irradiation.

Osteoblasts cultivated on TiN coated material revealed a highly significant increased expression of ITG-β1 (2.22 ± 0.42; *** p = 0.0007) and ITG-α1 (2.36 ± 0.28; *** p = 4.37 × 10 −5 ).

The exception was in 2020, when we noticed highly significant differences in the prevalence of E. faecium and E. faecalis , in comparison to 2017 ( p = 0.0007) and 2019 ( p = 0.0008), as well as a significant difference compared to 2018 ( p = 0.09).

Also brain tumors and/or sarcomas were overrepresented in the carrier families (28.6%, Table 2 ); the difference being highly significant when compared to the incidence of these cancers in the analyzed cohorts (5.1%, P = 0.0007, OR 7.4 95% CI 2.7–19.9).

Second, we excluded each individual participant at a time (while the others remained in the multiple regression model), which showed that the effect of Value-feedback remained highly significant throughout (mean P -value = 0.0007, weakest P -value = 0.003 when excluding patient 4).

Mice receiving iNO showed a modest but reproducible and highly significant enhancement in survival (p = 0.0007; Figure 1A ) compared to control mice breathing air alone.

The caffeine–MoCA association remained highly significant in the E3/E3 homozygous subgroup ( n = 45, p = 0.0007), demonstrating robustness to genetic stratification and ruling out confounding by APOE -related differences in caffeine metabolism or cognition.

The results show a highly significant effect of male genotype on insemination rates (X 2 = 14.437; d.f. = 2; p = 0.0007) but no effect of female origin (X 2 = 1.572; d.f. = 2; p = 0.4556) or interaction between the sexes (X 2 = 0.747; d.f. = 1; p = 0.3873).