“highly significant”

Second, we excluded each individual participant at a time (while the others remained in the multiple regression model), which showed that the effect of Value-feedback remained highly significant throughout (mean P -value = 0.0007, weakest P -value = 0.003 when excluding patient 4).

However, while the differences in age effects between control and case piglets were highly significant ( p = 0.0007, 0.0001, 0.0004), the three estimated positive slope values for diarrhoeic piglets were not significantly greater than zero ( p = 0.11, 0.39, 0.12).

Interestingly, IL-27 levels showed a moderate (R = 0.3781) albeit highly significant ( p = 0.0007) correlation with sPD-L1 levels, suggestive of a potential role for IL-27 in PD-L1 upregulation in vivo ( Figure 3 B).

The correlation was highly significant with a Pearson correlation coefficient ( r ) of −0.41 and p = 0.0007.

The exception was in 2020, when we noticed highly significant differences in the prevalence of E. faecium and E. faecalis , in comparison to 2017 ( p = 0.0007) and 2019 ( p = 0.0008), as well as a significant difference compared to 2018 ( p = 0.09).

The differences in % molting between the complete medium control and the negative non-specific antibodies control were not statistically different, while they are highly significant when the effect of monospecific anti- Ov -CPI-2 antibodies on molting was compared with the two controls ( P = 0.0007 and P = 0.028 respectively).

The results show a highly significant effect of male genotype on insemination rates (X 2 = 14.437; d.f. = 2; p = 0.0007) but no effect of female origin (X 2 = 1.572; d.f. = 2; p = 0.4556) or interaction between the sexes (X 2 = 0.747; d.f. = 1; p = 0.3873).

There was highly significant association of H2-tagging rs8070723-G allele with reduced risk of LOAD in the Mayo Clinic cohort (odds ratio = OR = 0.81, p = 7.0E-4) with remarkably similar OR estimates in the JS and RS series (Additional file 1 : Table S3) and in the independent ADGC cohort (OR = 0.89, p = 1.3E-4) (Table 1 ).

There was a highly significant correlation between HPyV6 DNA PCR and HPyV6 FISH results ( p = 0.0007; Fisher’s exact test).

Pixel-level quantification of GFP fluorescence demonstrated that the IL-13-induced inhibition of S protein-mediated viral transduction efficiency was highly significant ( P = 0.0007, Fig. 5C ).

The differences were highly significant at both 12 (P =0.0007) and 24 (P = 0.0115) weeks between the two groups.

Accordingly, while changes in scar mass mirrored changes in infarct size, viable tissue mass increased in CDC-treated patients (+13.0 ± 11.4 g at 6 mo), but not in controls (+0.9 ± 6.2 g at 6 mo), and the correlation between scar shrinkage and increased viability was highly significant (r = -0.59, p = 0.0007).

This increase in seropositivity with age was highly significant (logistic regression p = 0.0007).

There was no significant interaction of condition and night for the ON-OFF difference of all windows with more than two stimulations ( F cond x night (6,141.8) = 1.62, p = 0.15), the main factor condition was highly significant ( F cond(1,12.6) = 19.76, p = 7.1 × 10 −4 ) indicating that the lowSWA enhancement was persistent across 7 nights.

Further, in analyses of the GTEx (Genotype Tissue Expression) human post-mortem dataset containing samples from 53 non-diseased tissue sites for nearly 1000 individuals, we observed a highly significant correlation between GHR and MITF expression in sun-exposed (lower-leg; Pearson coefficient = 0.19, p = 0.00071) and not sun-exposed (suprapubic; Pearson coefficient = 0.25, p = 0.00011) normal human skin ( Figure 7 B).

However, we noted a highly significant interaction between line and diet in terms of final body weight ( P = 7.10 –4 ), specific growth rate ( P = 8.10 –3 ) and voluntary feed intake ( P = 5.10 –7 ).

Interestingly T→C mutations show even stronger strand asymmetry among phenotypic mutations, and are over-represented to a highly significant degree in the sense strand (P = 0.00071), but are not over-represented among incidental mutations.

Subsequently, CYPRI_cor was applied to the same patient cohort and yielded markedly stronger results, showing a highly significant association with the outcome measure IMPACT_orig (SE = 0.22; p = 0.00072), suggesting that the revised score maintains and potentially strengthens the relationship between CYPRI and clinical impact ( Figure 4 ) compared to the original model ( p = 0.0267).

Moreover, miR-374b was found to have highly significant overall complementarity with the consensus sequence ( P <7.3e−04).

Similarly, levofloxacin resistance was observed in all EEC isolates (100%, n = 53) but in 81.0% ( n = 34) of APEC isolates, showing a highly significant difference ( p =0.000731).

The statistical difference in endosome diameter between FUSwt and FUS501 was highly significant ( P -value=0.00074), but only a tendency between wild-type and FUS501 ( P -value=0.098) ( Fig. 4 B).

Overall, the interaction between MeAnSpring and MAT levels was also highly significant (LR Chisq = 14.4, P -value = 7.4e−4), suggesting DOY is dependent on the interaction between the interannual spring variation (e.g. anomalies) and the local historical temperatures from 1895 to 2022.

In the case of TNF stimulation, dasatinib caused a modest but statistically significant ( P = .013, n = 9) inhibition at as little as a 50nM concentration, whereas in case of C5a stimulation, a robust and highly significant ( P = .00074; n = 6) inhibition was achieved by 100nM dasatinib.

The overlap of ECACC-6 with Nf1 -Mouse-12 was highly significant ( P = 7.5 × 10 -4 ) as well as the overlap between two human groups ( P = 1.2 × 10 -3 ).

The association between this variant and ACR levels also remained highly significant in the replication study ( p -value = 0.000751).