“highly significant”

Among these, four genes showed high statistical significance ( G2E3, p = 0.0031, FC = 1.9; ZNF695 , p = 0.0096, FC = 2.0; CEP41 , p = 0.0023, FC = 2.2; RGPD1 , p = 0.0031, FC = 2.9), whereas the remaining six genes were highly significant ( NOL4, p = 0.0003, FC = 3.1; SOX6, p = 0.0003, FC = 3.2; GOLGA6C, p = 0.0002, FC = 5.9; PCDHA9, p = 0.0001, FC = 11; GOLGA6B , p = 0.0009, FC = 4.1; LMLN , p < 0.0001, FC = 3.4).

From trial 7 onwards, however, both single elements were discriminated from their compound, which was highly significant at the last acquisition trial (trial 10: Chi 2 -test; p < 0.0003; after Bonferroni correction), resulting in a stable and significant discrimination after 1 h consolidation time (MEM: Chi 2 -test; p < 0.0003; after Bonferroni correction). 3.4 Response latency decreased during multimodal learning Si

The increase of aversive behavior in response to the visual cue was highly significant in Mela(CTmGluR6)-treated ( p = 0.0003) and C57BL/6 mice ( p = 0.0026), but no behavioral change in response to the drifting stimulus was seen in untreated rd1 littermates ( p = 0.83, Fig. 7b ).

A highly significant positive association was found for the methylation site cg01089319 ( GAD1 gene) with two genetic variants of the gene GAD1 (rs2058725 ( P =0.0003) and rs2241165 ( P =2.61e−06)).

Again, the correlation between total anti-spike IgG and neutralizing antibodies was highly significant (p=0.0003; Figure 4D ), suggesting that the decrease in the number of specific antibodies goes in hand with the reduction in their neutralizing ability.

vivax attacks shows a highly significant positive correlation with maximum or overall P. falciparum parasitemia (R = 0.12 and 0.05, p = 0.0003 and 0.005 respectively) but negligible or no significance with P. vivax parasite density phenotypes (Maximum: R = 0.1 p = 0.02, not significant after Bonferroni's correction and overall: R = 0.07 p = 0.25), (iii) Maximum P. falciparum density shows a positive correlation with maximum P. vivax density (R = 0.22, p = 0.0002).

Differences between shimming methods were all highly significant ( p < 0.0003), apart from the comparison between dynamic shimming with 3rd-order spherical harmonics and dynamic shimming with the 8-channel MC-array ( p = 0.03).

However, in the SN ipsilateral to lesion, there were highly significant increases in extracellular DA in the SN after K + -infusion in striatum (F(1,11) = 27.9, p = 0.0003; Figure 6 F), with extracellular DA increasing by ~7-fold within the first 20 min.

Post-hoc t tests between groups (assessed at the p < 0.0125 Bonferroni-corrected level) showed the same highly significant pattern for both networks: AD < EC, EC > YC (all p < 0.0003) and no difference between YC and AD ( p > 0.1).

Our analysis revealed a moderate yet highly significant positive correlation (r 2 = 0.46, p ≤ 0.0003) between Z-AAT serum levels and the levels of human liver chimerism as determined by average human albumin serum levels ( Figure 3 F).

For patients with neutropenia who did not have systemic infection (group2), that is, those who were diagnosed with FUO or localized infection presented low concentrations of PCT (0,08–2,15) that were highly significant (p = 0,0003) and CRP concentrations that did not greatly differ statistically from those found in group 1 (19,5–546,0) (p = 0,9198).

At the 12-month follow-up, the difference was highly significant, with an OR of 15.51 (95% CI: 3.57–67.36); p = 0.0003 for four studies [ 5 , 17 , 18 , 20 ] strongly favoring the inverted ILM flap method for anatomical closure.

The increased incidence and number of metastases using the K1735p tumor was highly significant in C3H/ gld mice compared to C3H controls (difference in incidence between C3H and C3H/ gld P = 0.0003 using a one-sided χ 2 test; difference in number of lung metastases P < 0.0001 using a Mann-Whitney test).

The results revealed an overall highly significant increase in the expression levels of miR-155-5p in patients compared to controls ( p = 0.0003) ( Figure 3 A).

Results: MI was found to be varied, and the differences were highly significant among Group III and IV ( P = 0.0003) and Group II and IV ( P = 0.0007), and significant difference was found between Group I and Group II ( P = 0.0113).

Aphasic patients were older (56.69 ± 13.64) than non-aphasic patients (45.13 ± 12.84), with a highly significant difference of p = .0003 (t [52] = 3.83).

The results from the model indicated that there was no significant effect of treatment on the F: B ratio in the goat milk microbiome (p value = 0.67068), whereas the effect of timepoint was highly significant (p value = 0.000305).

One-way ANOVA showed highly significant group effects for both Tb.Th (F(2,6) = 41.32, p = .00031) and Tb.Sp (F(2,6) = 23.77, p = .00141).

Evidence for recombination was supported by highly significant PHI test values ( P = 3.17E−4; Fig. 2 ).

Statistical analysis by two-way ANOVA revealed a highly significant interaction between the effects of the Vav-Cre and Syk flox/flox mutations ( p = 0.00032 and 0.00003 for males and females, respectively), indicating that Cre-mediated deletion of Syk in Syk Δ Haemo mice strongly increases trabecular bone mass.

The R and Rh samples showed highly significant species richness compared with the BK samples ( p = 3.23E-04 and p = 5.91E-06, respectively), whereas no significant differences were observed within each sample type.

The difference between heterotrophic and autotrophic free energy of the 5′UTR was highly significant ( P = 3.27 × 10 − 4 ) with median values of − 2.1 kcal/mol and − 3.4 kcal/mol for increased and decreased TE, respectively (Additional file 12 : Figure S2b).

2d ), showing a highly significant association between ecDNA in Barrett’s oesophagus biopsies and progression to EAC (Fisher’s exact test, P = 3.3 × 10 −4 , one-sided). ecDNA can arise in high-grade dysplasia The design of the longitudinal case–control FHCC study enabled the timing of ecDNA development in Barrett’s oesophagus segments to be determined in patients with a cancer outcome.

These data showed a highly significant difference ( P = 0.00033) in the reduction of plaque diameter caused by the deletion of Vhs between Caco-2 cells (2.123- ± 0.096-fold) and tetherin-depleted Caco-2 cells (1.588- ± 0.070-fold).

A highly significant effect (corrected p -value = 3.362 × 10 −4 ) was identified for an SNP 168 kb up-stream of the BDNF transcription start.