This trend was highly significant ( P = 0.0002), partly because of a large sample size (550 pictures), yet not very steep ( b = −0.057).
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Overall, there was no significant effect of blister type on vaccination success based on dyed water marker (χ2 = 0.3145, df = 1, p = 0.5749), but there was a highly significant effect of bait type on vaccination success (effectiveness) (χ2 = 17.52, df = 2, p = 0.0002).
However, lower pressure still resulted in highly significant release of the REMIS markers from the brain ( Fig. 2e , left-most panel, P = 0.0002, n = 7, ratio-paired t test).
Indeed, a highly significant correlation (R=0.9589, p=0.0002) was observed when the automated measurements of myofibril CSA from each ROI were compared with the mean of the manual measurements.
This analysis revealed highly significant dependencies between FAA and the six EDA features (all p < 0.0002 ), indicating robust non-linear relationships.
At both temporal stages, the anterior/posterior differences in Shh /ZRS colocalisation frequency were highly significant (E10.5: P =0.0002; E11.5: P =0.0001).
At the same time, 4 patients encountered graft-rejection, and 7 patients died of HSCT-related complications, indicating a highly significant impact of HSCT on the survival rate of patients with actinopathies ( p = 0.0002, Figure 3 ).
Results Flexion/extension ROMs (average ± S.D.) were 18.1 ± 3.3°, 19.9 ± 7.5°, and 1.5 ± 0.7°, respectively for the intact, injured/fixed, and injured/8-week groups, with the differences being highly significant for the injured/8-week group (p=0.0002).
Interestingly, our data revealed that a highly significant increase in myocilin expression (11.8-fold) was observed in TM region of the responder eyes compared to vehicle-treated eyes ( p = 0.0002); and there was a fourfold increase in myocilin expression in GC responder eyes ( p = 0.0004) compared with GC non-responder eyes.
A highly significant interaction emerged with factors WordType, PeriExtra, TempFront and Areas ( F 2, 22 = 14.012, p < 0.0002), revealing different CA circuits across the 12 area network between object- and action-related words.
These curves clearly show that while thirds of IL-6 showed little discriminative ability in separating risk for nonfatal CVD in unadjusted models ( p = 0.13), associations with risk for fatal CVD events, fatal other CV events, or non-CVD mortality were all highly significant ( p ≤0.0002 for all).
We found a modest but highly significant increase in Sgg::YFP levels at stimulated NMJs (12.4 ± 0.02%; P = 0.0002, Student’s t test; Fig. 8, I–K ).
The results as shown in Figure 5B , demonstrated a highly significant correlation for RIα up-regulated genes ((p < 2E-4) and RIIβ down-regulated genes (p < 1E-11) and the gene expression differences which distinguish myoblasts from myotube cells.
However, during reversal phase, the analysis of trials to criterion revealed a highly significant effect of WD in both 7 and 16 months old mice (Two-way ANOVA p = 0.0002, Bonferroni post tests * p < 0.05; Figure 1D ).
Comparison of the combined values with T112i3 mAb to the values without T112/3 mAb showed that the effect of CD2 activation on mo- tility was highly significant, p = 0.0002.
The difference between the means of the fold-inhibition values of TRIM22 shRNA (1.4-fold) and the pooled controls (4.5-fold) was highly significant (P = 0.0002 Mann-Whitney) ( Figure 3E ).
Analysis of IL-18 (mean [min/max]: 2,385 [300–8,025] pg/ml) and ECP (mean: 1,509 [<100/4,625] ng/ml) in 23 paired samples showed a highly significant correlation (r s = 0.70, P = 0.0002) between this cytokine and the eosinophil-derived product in the airways.
More importantly, there was a highly significant ( p -value = 0.0002, R 2 = 0.9944) dependence of HSP60 expression on the concentration of sodium ( Fig 1C ).
A highly significant association was observed between IDH 1 status with respect to OG (p = 0.0002) and astrocytoma (p = 0.005).
3C–F ; the decrease was highly significant in the lung ( P = 0.0002) and almost achieved significance (p = 0.069) in the heart).
Both regressions were highly significant ( p -value = 0.0002 for seed viability and <0.0001 for seed counts).
While our finding of an increased incidence of DQA1*03:01 in the cases (OR 2.81 [1.36–5.81], p = 0.005) is very similar to the findings reported for this class II allele in the previous study, we obtained no evidence for a significant alteration in HLA‐B*57:01 frequency among our cases and instead see a highly significant increase in frequency of the HLA‐B*44 family (5.33 [2.45–11.61], 2.5 × 10 −5 ), including a strong association with the B*44:03 allele (6.01 [2.37–15.28], p = 0.0002).
Polygenic risk scores (PRS) for reproductive aging phenotypes and breast cancer risk The correlations between the PRS for each reproductive aging phenotype and the phenotype itself were highly significant as expected (p≤0.0002); yet the strength of the correlations was weak (correlation coefficient 0.16–0.21) ( Table 6 ).
9 , bottom row); these differences were significant for all groups including the LVS Δ capB vector in experiment 1 (ranging between P < 0.05 to P < 0.01) and for all but the parental vector and one vaccine in experiment 2 (ranging from P < 0.05 to P < 0.0001); combining all LVS Δ capB and r LVS Δ capB /Bp vaccines, the increase in antibody to HI Bp82 was highly significant ( P = 0.0002 and P < 0.0001 by two-tailed t test in experiments 1 and 2, respectively).
Regression analysis confirmed a highly significant correlation between expression of CXCL11 and TBET (p=0.0002), or Granzyme B (p=0.0055), respectively (Figure 4C ), but not between CXCL11 and GATA3, RORC or FOXP3 (not shown).