“highly significant”

Notably, we found the rate of overlap with Neanderthal introgressed segments to be highly significant ( P < 0.0002, permutation test) ( Fig. 2B ), supporting the hypothesis that certain NUMTs were introduced into the modern human genome via archaic admixture rather than by chance.

The effect of manufacturer on overall (global) taxonomic abundance was highly significant (p<0.0002).

Apparent survival The U-CARE goodness of fit global test was highly significant (χ 2 = 36.93, d.f. = 12, p = 0.0002).

A permutation test with 10,000 randomizations confirmed that this difference was highly significant ( p = 0.0002), indicating that the higher species richness in GS is unlikely to arise by chance.

The results shown in Figure 3 , demonstrate a highly significant improvement in the survival time in Aldoxo-treated mice as compared with control or Doxo-treated mice ( P = 0.0002 for each comparison).

Statistical analysis confirmed that these differences were highly significant (ANOVA, F (2,6) = 45.31; p = 0.0002; R 2 = 0.9379), indicating that the type of treatment substantially influenced SOD response.

The difference between the frequency of nodal involvement in the patients without distant metastases (21.5%) and those with metastases to an osseous (39.0%) or visceral site (50.9%) was highly significant ( P = 0.0002); that between those whose first distant metastasis was to the viscera and bone was not statistically significant ( P = 0.249).

The differences between the populations are highly significant for both Cmax values, as determined by 3-group permutation ANOVA (p < 0.0002 for both) and pairwise Wilcoxon test for sparse vs dense (p = 2e-18 and p = 9e-14 for Cmax = 90 nM and 900 nM, respectively).

In contrast, the reduction in leukocyte counts was highly significant (P = 0.0002, F = 6.11) at the 0.05 level.

These results were corroborated by PERMANOVA, which confirmed no significant difference between the two rhizosheath communities (Permutation tests, R = 0.256, p = 0.089) but a highly significant difference between the rhizosheath and bulk soil communities (Permutation tests, R = 0.9, p = 0.0002) ( Figure 4 a,b). 2.3.2.

The amount of FD4 diffusing through the monolayer (measured by the permeability coefficient, P app ) treated with TGFβ3 was about 10fold higher (highly significant, p = 0.0002) compared to an untreated monolayer ( Fig. 2 ).

This was a highly significant difference ( p = 0.0002).

Because both factors and the interaction were highly significant (p ≤ 0.0002), in the next step we performed one-way ANOVA with Tukey post hoc test separately for each generation.

However, there was a highly significant decline in the amplitude of the AHP in all cells by 13.5 + 3.2% ( n = 12, P = 0.0002) ( Fig. 7 A and D ).

The difference in visual grading was also statistically highly significant for the three groups in post stress ( p = 0.0002), and a similar difference was noted at rest ( p = 0.004) ( Table 4 ).

We performed qPCR analysis to detect the expression of AKAP12α and AKAP12β isoforms using isoform-specific primer sets and found less significant reduction in AKAP12β gene expression in tumor tissues (P=0.0594), whereas the reduction in the expression of AKAP12α gene in tumors was highly significant (P=0.0002) ( Fig. 1B ).

This analysis revealed highly significant dependencies between FAA and the six EDA features (all p < 0.0002 ), indicating robust non-linear relationships.

Notably, males endorsing neutral ER were adherent (PDC = 85.6%, SD 24.1, n = 34), while their female counterparts were less adherent (PDC = 57.1%, SD 34.1%, n = 32), a highly significant difference ( F value = 15.3, P = 0.0002).

For confirmation, we applied IFNA16 rs28368163 as a tag SNV in a second ET validation cohort (n = 54) and reconfirmed a highly significant association ( P = .0002) and OR (4.51; CI, 1.92-10.56), nearly identical to that found in Cohort 1 ( Table 2 ).

A highly significant ( p = 0.0002) QTL, located at 38.46 cM (D19Mit53) on chromosome 19, had a LOD score of 5.78.

When the tumour volumes at day 4 post-treatment were compared to untreated tumour volumes at day 4, there were highly significant differences (p < 0.0002) at all doses (Table 1 ).

This is also confirmed by the results of the ANOSIM test, wherein there was a strong and highly significant difference in assemblage composition among habitat alteration types (ANOSIM R = 0.759, P = 0.0002).

The Japanese rater indicated deterioration more frequently than the Vietnamese rater (Table 3 ); this difference was considered highly significant for both JVCS and CRRS by the symmetry test ( P = 0.0002 and 0.0008, respectively, by Bowker's test).

9 , bottom row); these differences were significant for all groups including the LVS Δ capB vector in experiment 1 (ranging between P < 0.05 to P < 0.01) and for all but the parental vector and one vaccine in experiment 2 (ranging from P < 0.05 to P < 0.0001); combining all LVS Δ capB and r LVS Δ capB /Bp vaccines, the increase in antibody to HI Bp82 was highly significant ( P = 0.0002 and P < 0.0001 by two-tailed t test in experiments 1 and 2, respectively).

The difference was highly significant ( P = 0.0002, Student t test, 2-tailed).