These curves clearly show that while thirds of IL-6 showed little discriminative ability in separating risk for nonfatal CVD in unadjusted models ( p = 0.13), associations with risk for fatal CVD events, fatal other CV events, or non-CVD mortality were all highly significant ( p ≤0.0002 for all).
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A highly significant ( p = 0.0002) QTL, located at 38.46 cM (D19Mit53) on chromosome 19, had a LOD score of 5.78.
Furthermore, they did a subgroup analysis on further cleaved and uncleaved embryos-’revealed that highly significant pregnancy rates were observed when ≥2 cleaved embryos were transferred (42.2%) than when 1 cleaved embryo (16.9%, P = 0.0002) or embryos without cleavage were transferred (3.2%, P ≤ 0.0001)’.
This difference was highly significant (GROUP effect: F = 21.18; P = 0.0002; Fig. 3a ) and was apparent during both the ramp and hold phases, and at both force levels (P = 0.01).
As expected, a highly significant correlation was observed between the number of Gag escape mutants associated with the protective HLA alleles and decreasing VRC (r = -0.33, p = 0.0002, Fig 4A ).
The time domain features showed a highly significant distinction ( p -value = 0.0002), indicating a clear dissimilarity between the AD and baseline groups in this domain.
Moreover, a statistically significant ( P < 0.004) interaction between the organ sampling-time and the SNP treatment was revealed in kidney regardless of the dosing time, whereas a highly significant ( P < 0.0002) interaction was validated in liver only in animals injected at 13 HALO. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.
Using a permutation test, we found that the separation in monophyly score between core and accessory genes is highly significant (p = 0.0002).
One is that advanced stages (RAEB and RAEB-t) had a highly significant association with the frequency of abnormal karyotypes ( P < 0,0002), evolution of disease ( P < 0,0001), and mortality ( P < 0,0005).
A highly significant statistical correlation between WGA fluorescence and the degree of dysplasia was found ( P =0.0002), with areas of HGD and cancer showing lower fluorescence intensity and WGA binding relative to areas of non-dysplastic BE and normal esophageal mucosa.
However, a highly significant group-by-sex interaction was detected for both genes ( p = 0.00020–0.00080).
This difference in nodal metastasis as per subsite was highly significant (Chi-square = 19.410, degrees of freedom/d f = 5, p = 0.0002).
Furthermore, the presence of organ failure at the time of hospital admission according to the Sepsis-3 definition (35 patients out of the 60 patients) and the detection of bacteremia (30 patients) showed a highly significant association (Fisher’s test, p = 0.0002).
The difference between the frequency of nodal involvement in the patients without distant metastases (21.5%) and those with metastases to an osseous (39.0%) or visceral site (50.9%) was highly significant ( P = 0.0002); that between those whose first distant metastasis was to the viscera and bone was not statistically significant ( P = 0.249).
The different trends were highly significant ( F 2,41.6 = 10.64, P = 0.0002).
A highly significant difference in distribution of deaths by suicide (χ 2 = 36.20, df = 11, p = 0.0002) was shown, which were found in both genders (Male: χ 2 = 21.00, df = 11, p = 0.0335; Female: χ 2 = 47.74, df = 11, p = 0.00002).
Based on statistical analysis, results show a strong highly significant influence effect of the harvesting year ( p = 0.0002) on DON content, which is more than doubled for the harvesting year 2020 (mean of 3746 μg kg −1 vs. 1463 μg kg −1 ).
This difference is highly significant (p = 0.0002, chi-square test). 4.
After adjusting for sex and health status, age-dependent changes remained highly significant in the N/NS pathway control ratio (slope = −0.0007, SD ± 0.0002, P = 0.0002) and the S/NS pathway control ratio for PBMCs (slope = 0.0010, SD ± 0.0002, P = < 0.0001) (Fig. 2 , Supplementary Table 5 ).
The median plaque score difference on the 100 th day between the two groups was highly significant (p ≤0.0002).
Relative gene expression Expression of cannabinoid receptor 1 (CB1R) is increased after ELS and FS Two-way ANOVA analysis revealed no significant main effects for ELS [ F (1,31) = 0.5555, p = 0.4617] or FS [ F (1,31) = 0.2117, p = 0.6487], but a highly significant interaction between these two stressors was found [ F (1,31) = 18.48, p = 0.0002].
The results shown in Figure 3 , demonstrate a highly significant improvement in the survival time in Aldoxo-treated mice as compared with control or Doxo-treated mice ( P = 0.0002 for each comparison).
For example, MNU produced a highly significant ( p < 0.0002) increase in nuclei of > 90.1 μm 2 from 19 to 38%.
By 17 weeks, the RNFL showed progressive thinning, with a highly significant difference between CON and gOHT groups (p = 0.0002).
A highly significant association was observed between IDH 1 status with respect to OG (p = 0.0002) and astrocytoma (p = 0.005).