The univariate Kaplan–Meier analyses in both cohorts ( Figure 2 G,N) nevertheless demonstrate robust and highly significant survival differences ( p < 0.0001), confirming a consistent biological signal.
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Results and Discussion In comparing methods of assessment of fungal growth on control media and media amended with fenbuconazole using inhibition ratios, the fixed effect Media*Day*Method was highly significant for Ratio 0 and Ratio A , having p-values of p<0.0001 (for Ratio 0 , F 23, 2033 = 259.27; for Ratio A , F 23, 2033 = 273.35).
Fitting a generalized linear model with negative binomial errors to the data on number of thalli per individual from infected nests (fitted dispersion parameter θ = 4.39) showed a highly significant difference between nests in the level of infection (Wald χ 2 = 245.05, df = 1, p < 0.0001), and also a strong effect of estimated worker age (Wald χ 2 = 70.3, df = 4, p < 0.0001), with older workers having a higher load of thalli (Fig. 7 ), but no association with the presence or absence of P. alcon caterpillars (Wald χ 2 = 0.719, df = 1, p = 0.396).
All vaccinated groups showed 0% mortality when challenged, which was highly significant compared to the non-vaccinated controls (40 and 28% mortality eight and twenty-six weeks post vaccination (wpv), respectively) (P<0.0001).
The concentration of poloxamer 407 exhibited a highly significant effect ( p < 0.0001), while the quadratic term (A2) was also significant ( p = 0.0059).
The spatial variability of Rhodes grass productivity was observed to be of the same trend as indicated by the highly significant spatial correlation between the CNDVI values of the first and second harvests, with a correlation coefficient ( r ) of 0.74 ( p = 0.0001).
However, over the course of 6 months post-second dose, 111/113 (98.5%) LTCH staff exhibited highly significant decays ( P < 0.0001) in anti-spike and anti-RBD IgG antibody levels with approximate half-lives of 63 (31–73) days and 57 (28–71) days, respectively, ( Fig. 5A through F ).
There are highly significant differences of SOD level between rural and urban (P value 0.0001) on the one hand and between rural and industrial area (p ≤ 0.0001) in other.
This analysis revealed a highly significant effect of condition, F (2, 78) = 19.2, P < 0.0001.
Measures depend on age-group overall [ F (1.79, 459.04) = 70.74; P < 0.0001] and a highly significant interaction is found between test and age group [ F (16.08, 459.04) = 17.84; P < 0.0001].
Statistical analysis confirmed a highly significant positive correlation between IGS size and 45S rDNA consensus length (Spearman’s ρ = 0.937, p < 0.0001), providing strong evidence that IGS expansion may be the primary driver of variation in 45S rDNA unit length across Characiformes species.
genurostris showed highly significant association with pH (χ 2 = 27.16, df = 3, p < 0.0001) and temperature (χ 2 = 10.55, df = 3, p < 0.014)—a hump-shaped curve, peaking at 7 pH and dropping down at temperature between 28 and 30 °C (Fig. 6 ).
The post-hoc Dunn’s test showed highly significant differences between the NV group and the vaccinated animals: SC (mean rank difference = −98.67, p < 0.0001) and ID (mean rank difference = −153.0, p < 0.0001); as well as significant differences between SC and ID (mean rank difference = −54.30, p = 0.0002).
Most strikingly, we detected a highly significant positive relationship between thigh and pectoralis mitochondrial content (correlation coefficient 0.61; P <0.0001).
First, the 3 × 3 TSM table for a candidate C‐PAS must show a highly significant targeting preference ( P < 0.0001, 8 df).
Consequently, the Group × Task × Trait interaction remained highly significant (β = 0.89, SE = 0.19, Z = 4.59, p < 0.0001).
Highly significant reductions in the number of bouts were found with MPG [ F (3,28) = 10.62, P < 0.0001] (10, 20 mg/kg; 0–8 h, P < 0.001) (Fig. 2a ), Vit-C [ F (3,28) = 9.985, P = 0.0001] (100–300 mg/kg; 0–4 h, P < 0.001) (Fig. 2b ), GP [ F (3,28) = 50.97, P < 0.0001] (50–150 mg/kg; 0–8 h, P < 0.001) (Fig. 2c ) and BM-ButFr [ F (3,28) = 48.28, P < 0.0001] (5–20 mg/kg; 0–8 h and 13–16 h, P < 0.001) (Fig. 2d ).
When the data from all five experiments are pooled, this reduction is very highly significant ( P <0.0001).
As described above, maximal respiratory capacity of cells, was significantly lower in the cells cultured for 8 days in HG when compared to the controls, and this reduction became highly significant (P<0.0001) after 12 days of culture in HG, with 3 fold reduction of maximal OCR (P<0.0001, Fig. 3 A) and 4 fold reduction in the reserve capacity when compared to cells cultured in NG (P<0.001).
The difference in seropositivity according to island was highly significant (p<0.0001).
This effect was highly significant ( p < 0.0001) ( Figure 1 E,F).
There were also highly significant differences in cell-count ratios between isolines selected for large and small body size ( p < 0.0001).
By contrast, there was a highly significant and strong effect of species ( R 2 = 0.5048, p < 0.0001), with pairwise tests indicating cranial shape differences between 16 of the 45 pairwise comparisons ( table 2 ).
Moreover, the pseudogenes expression showed a highly significant positive correlation between pairs of genes: HERC2P2 and SDHAP1 (R = 0.626, p < 0.0001), HERC2P2 and AURKAPS1 (R = 0.233, p < 0.0001) as well as AURKAPS1 and SDHAP1 (R = 0.328, p < 0.0001).
The results of the five models (extensive caries, initial caries, root caries, chronic gingivitis and chronic periodontitis) indicated that the models were highly significant, with p values < 0.0001 in all cases.