“highly significant”

Highly significant differences ( P <0.0001) were observed in allele, haplotype, and phenotype distribution across the three Color groups.

There was a highly significant progression towards more complexity, with lower Bloom's scores in Cycle 1 relative to Cycle 2 (mean difference = 0.42, Wilcoxon rank sum test W = 2044567, P < .0001), and lower in Cycle 2 compared to Cycle 3 (mean difference = 0.84, W = 120920, P < .0001).

By contrast, for HCC44, the most imetelstat sensitive line, the difference was highly significant ( p < 0.0001).

For MM, sex was found to be a highly significant (p<0.0001) main effect with males showing an overall larger MM than females.

Remarkably, MV2C, the histotype of which is virtually indistinguishable from that of MM2C, showed a large predominance of the 129 M allotype, with resPrP D -129 M accounting for 83 ± 7% of total resPrP D , a difference between populations of resPrP D -129 M and -129 V statistically highly significant ( p < 0.0001).

The impact of the respondents' perception of local professional norms regarding disclosure on their attitudes and behaviours was substantially highly significant (p<0.0001) and, importantly, it was independent of local culture.

The model was highly significant ( p < 0.0001), with a coefficient of determination R 2 = 0.99 and an adjusted R 2 = 0.98, indicating that the model accurately explains the variability in the response.

As shown by the ANOVA, the T exerted a highly significant effect on Tg (F = 147.11, p < 0.0001).

A strong and highly significant knock-down of expression ( P < 0.0001, n = 12) was detected 3 days post-agroinfiltration ( Figure 5 ).

* indicates p‐value 0.01 to 0.05 (significant) ** indicates p‐value 0.001 to 0.01 (very significant) *** indicates p < 0.001 (highly significant) **** indicates p < 0.0001 (extremely significant) 4.14.

The results of univariate and multivariate analyses demonstrated that AST was a highly significant ( P < 0.0001) independent predictor of liver fibrosis stage.

In Table 3 , it can be seen that the model is highly significant ( p < 0.0001, f = 62.17), and the lack of fit is not significant ( p > 0.05, f = 1.44).

coluzzii populations An overall highly significant elevated levels of AChE (F 2, 237 = 55.93, P < 0.0001) and β-esterase (F 2, 237 = 159.0, P < 0.0001) activities were observed in both indoor and outdoor mosquito populations compared to the susceptible reference strain, Kisumu (Figs. 3 a–d).

The superior performance of SHuffle strains ( Fig 1 ), supported by highly significant ANOVA results (F (11,24) = 45.32, p < 0.0001), validates recent emphasis on engineered redox systems for disulfide-rich proteins [ 44 ].

The model explained 77.8% of the total variation in the observed number of eggs per snail which was highly significant (PROC NLIN: F 3,729 = 853.8; P < 0.0001).

Untreated cells (a) showed a highly significant difference (**** p < 0.0001) compared with all other groups.

Finally, site had a highly significant effect on flower height above ground level (X 2 = 344.16, df = 2, p <0.0001).

Results of multivariate analyses showed highly significant effects of flow [Pillai’s V = 0.579; F(3,255) = 116.9, P<0.0001] and of speed [Pillai’s V = 0.367; F(12,771) = 8.95, P<0.0001].

The differences were statistically highly significant ( χ 2 = 1689.11, P < 0.0001).

These values were greater than zero for both ACT (Mean = 77.18 μV; t (17) = 6.88, p<10 −7 ) and PASS (Mean = 32.04 μV; t (17) = 3.25, p<0.002), and the difference between ACT and PASS was highly significant (t (17) = 5.5, p<10 −4 ).

An analysis of independent contrasts based on this hypothetical relationship gave a highly significant relationship between WPM and r diff both when within-species variation was ignored ( β = 5.48, t = 6.57, df = 48, p < 0.0001) and included ( β = 6.59, t = 9.12, df = 55, p < 0.0001).

34 A highly significant association also was observed using this alternative measure ( P < .0001; Table V ; available at www.jpeds.com ).

While each inhibitor separately was unable to significantly decrease the rate of tumour growth, their combination induced a highly significant 27% decrease in growth rate ( p < 0.0001, Mann-Whitney test) (Figure 7A ).

The trim-and-fill analysis imputed two additional studies, resulting in an adjusted pooled HR of 1.24 (95% CI: 1.13–1.37), which remained highly significant ( P < .0001) and similar to primary analysis.

This contrasts sharply with the highly significant differences noted in spleen size and splenocyte number ( P < 0.0001) of sTg MTAG mice compared with the wild-type controls.