Considering wild-derived and lab-derived strains independently, principal component analyses (PCA, an unsupervised linear feature extraction method that discovers the directions of maximal variances in data) found highly significant correlations between non-synonymous SNP distribution and phylogeny within lab strain V2Rs (Two-way ANOVA, variance by V2R clade F 12,858 = 17.99, P < 0.0001).
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The correlations between the ELV and the other two lung volume indices (EELV CT and EELV MBW,He ) were somewhat weaker (r = 0.58 and r = 0.76), but still highly significant (p < 0.0001).
Gal-9 induced a substantial, highly significant ( P < 0.0001), and dose-dependent increase in SARS-CoV-2 cell-surface attachment ( Figure 2 A).
While both monotherapies induced a modest increase in CD69 expression, the combination treatment led to highly significant upregulation compared with the vehicle ( p < 0.0001 for CD4+, p = 0.0005 for CD8+, Dunn’s test).
Fisher's exact test ( http://www.langsrud.com/fisher.htm ) revealed a highly significant accumulation of stop codons in the 3c sequence of FIPVs compared to FECVs (p < 0.0001). 4.
Moreover, 8 classes, including CE, CER, DAG, FFA, LPC, PC, SM, and TAG, showed highly significant differentiation with p -values < 0.0001 ( Table 1 ).
sclerotiorum populations from the four different countries with the R ST fixation index statistic highly significant ( P < 0.0001) for pairwise combinations of England/Norway ( R ST = 0.094), England/Australia ( R ST = 0.186), Scotland/Norway ( R ST = 0.068), Scotland/Australia ( R ST = 0.152), and Norway/Australia ( R ST = 0.198).
Notably, transcript levels of the photoperiod insensitive Ppd-A1a allele were not significantly affected by photoperiod in this dataset, whereas those of the Ppd-B1b allele showed a highly significant effect of photoperiod ( P < 0.0001).
A highly significant correlation between IGF-1 and IGFBP-3 on a molar basis ( r = 0.84; P < 0.0001) has been revealed.
A linear regressing analysis was also performed on the data from the HT assay and AHT device ( Figure 3 B), which demonstrated a highly significant correlation coefficient close to one ( R 2 = 0.998, p < 0.0001).
Likewise we found a highly significant dose-dependent effect across all treatments for the rate of adverse events leading to discontinuation ( p < 0.0001), yet a nonsignificant (retigabine, lacosamide) or small (eslicarbazepine; p = 0.0276) impact of dose variation on the rate of seizure freedom (most likely due to limitations of rare event analysis).
The autoregressive parameter β 1 , however, was highly significant (estimate = 0.76248, SE = 0.0988, Z = 7.7178, p = 0.0001), suggesting that current FAW populations were strongly dependent on their previous values, highlighting the importance of temporal autocorrelation in FAW population dynamics.
Both terms were again highly significant ( p < 0.0001 for both), but together only explained 13% of the variation in AAA.
All variables included in the SDMs were highly significant for both the pine and the disease (p-value < 0.0001).
Results ANOVA showed a highly significant effect of time in all the horses for the vitamins studied ( p < 0.0001).
While the inhibitory effect of DHP/Alg was less pronounced compared to antibiotic treatment, exposure to 75 μg/mL DHP/Alg resulted in a highly significant reduction in both 16S and 23S rRNA levels (p ≤ 0.0001 for each) relative to CtE-infected untreated controls.
Other covariates such as age, educational level, working status, participation in social activities, perceived health status, regular physical activities, and weight change of ≥5kg in the past year were also highly significant for both men and women ( p < 0.0001).
In the present investigation, the experimental group demonstrated a highly significant reduction in waist circumference from 98.84 ± 5.66 cm to 92.41 ± 5.40 cm following the intervention (p < 0.0001).
An objective validation of the self-reported smoking history of a randomly selected sub-sample immigrant group, using expired carbon monoxide (CO) measurements, showed a highly significant correlation coefficient (r = 0.64) of expired CO levels with the reported number of cigarettes consumed (p < 0.0001).
Nevertheless, based on the data on dietary fat consumption in China over the past 30 years, we believe that there is a highly significant correlation ( p < 0.0001) between excessive fat intake and CVD.
Two-way ANOVA revealed a highly significant main effect of diabetic status on muscle volume (F(1,34) = 119.04, p < 0.0001), with diabetes accounting for 74.08% of the total variance.
The differences among groups were highly significant at each time point ( p < 0.0001).
Specifically, for thermal pain measurements, both the MA and AR manipulations showed highly significant increases in AAT compared to AII (both P < 0.0001).
There was a highly significant relation between TOSS and FOXP3 gene polymorphism in allergic conjunctivitis patients, p = 0.0001 as displayed in Table 4 .
MYOCD x CSPG4 correlations were highly significant across the brain regions examined in this analysis (P < 0.0001 throughout).