“highly significant”

A two-way ANOVA detected a highly significant effect of light on E PAR (F1,74= 132.20, p < 0.0001) and a significant species vs. light interaction (F3,74 = 9.71, p < 0.0001), while for the main effect of species no significant differences were detected ( p = 0.627).

Decoding of uncued orientations was highly significant on both Switch (1–1.4 s after cue onset, corrected p = 0.0001) and Repeat trials (1.05–1.4 s, p = 0.0028, Switch > Repeat 1.25–1.4 s, p = 0.0295; Fig. 5 A , left panel inset).

The mesh count raw data (Figure 2 C) show that 40 nM Ov -GRN-1 increased the mesh count from the medium only control of 9.7–15.7 meshes—a highly significant ( P < 0.0001) relative increase over the blank control of 62% (Figure 3 A).

Thus, both lubricant and counterface roughness had a highly significant effect ( p < 0.0001, two-way ANOVA) on wear, and the effect of counterface roughness depended on the lubricant ( p < 0.0001, interaction term) ( Figure 2 ).

The one-sample t- test comparing the sample mean 2.1 with 3, the score signifying no change, was highly significant, t (566) = − 24.6, p < 0.0001, d = − 1.0.

For all 3 parameters the contrast between LPS and saline was calculated up to 24 hours postinjection and was highly significant ( P < .0001).

The Mann–Whitney test showed a highly significant difference between survivors and non-survivors for serum GLCA-3S concentration ( p -value < 0.0001).

Statistical analysis for color strength (Two-Way ANOVA with interaction) Statistical analysis provided in the Table 5 confirm that (a) Fabric type has a significant effect on K/S ( p < 0.001), (b) Binder ratio (gelatine: alginate) has a very strong and highly significant effect ( p < 0.0001), (c) Dye concentration significantly affects K/S ( p < 0.0001), and d) There is also a significant interaction between fabric and ratio ( p < 0.001), meaning that the effect of the binder ratio depends on the fabric type.

Cryoprecipitate use followed a similar trend, showing a highly significant p - value [ p < .0001] and providing strong evidence against the null hypnosis.

The t-test revealed that no significant differences in HI were observed within lines in NIL15-YXZ or NIL15-SBSM ( p > 0.05), but highly significant difference in mean HI was observed between NIL15-YXZ and NIL15-SBSM ( p < 0.0001).

There were highly significant correlations ( r = 0.89, p < 10 –4 in Paris) and good intraclass correlation coefficients ( R = 0.89 in Paris) between the two series of values.

In contrast, spheroids in the NAFLD group featured highly significant increases in expression of G6PC (6.2‐fold; P < .0001), PCK1 (6.1‐fold; P < .0001), and FASN (13.3‐fold; P < .0001).

Furthermore, the clinical score differences on day four revealed highly significant intergroup variations, with P-values of <0.0001 for LPS + DH-HQ vs LPS, 0.0005 for LPS + DH-HQ vs LPS + DH, and 0.0028 for LPS + DH-HQ vs LPS + HQ (P < 0.005) ( Figure 14A ).

They found a small, but highly significant, decline in the strength of reported correlations with publication date (best model: P < .0001; R = -0.133) and with sample size (best model: P < 0.002; R = -0.188).

Statistical findings reinforced this approach: A one-way ANOVA on mean percent change in Cp showed a strong group effect [F(2,36) = 50.42, p < 0.0001)], with post hoc Tukey HSD tests revealing no significant difference between Non-Responders and Placebo (mean difference = 0.25%, p = 0.998), but large, highly significant differences between Responders and Placebo (mean difference = 35.74%, p < 0.0001) and Responders and Non-Responders (mean difference = 35.49%, p < 0.0001).

The difference was highly significant ( p = 0.0001).

The 60–100 Hz Gamma Range Gamma power (60–100 Hz) was most dramatically affected by MEC inactivation (Figure 3i ), showing highly significant reductions in all layers: stratum lacunosum moleculare (71.1% reduction, p = 0.0001, p_FDR = 0.001, d = −2.95), stratum radiatum (46.1% reduction, p = 0.0007, p_FDR = 0.004, d = −2.28), and stratum pyramidale (53.0,0.001,% reduction, p = 0.001, p_FDR = 0.004, d = −2.23).

Highly significant interactions were observed between a MDD status and alcohol frequency (all p values ≤ 0.0001).

ELISA results showed that the Giardia induced a highly significant increase in the secretion of IL-6, IL-12 p40 and TNF-α compared to the control group (IL-6: ANOVA, F (4, 10) = 1.116, p < 0.0001; IL-12 p40: ANOVA, F (4, 10) = 0.6885, p < 0.0001; TNF-α: ANOVA, F (4, 10) = 1.990, p < 0.0001) (Fig. 2 a–c).

By aggregating the two subgroups with low risk and three subgroups with medium risk, patients could be assigned to three risk groups (high, medium, low) with a highly significant ( p < 0.0001) five-fold difference in risk (Table 5 and insert in Fig. 2 ).

However, in the replacement study designed to mimic the “real world” uncontrolled clinical practice setting, there was a highly significant (p < 0.0001) IOP effect when switching from the concomitant use of the individual components to the FCDT, as 81.1% patients had an IOP equal to or less than the starting IOP.

A cell‐derived H7N1 vaccine protected mice from disease and weight loss Vaccination induced a highly significant reduction in the signs of infection ( P < 0·0001) ( Table 1 , Figure 3B ).

There was a highly significant trend in risk ( P =<0.0001).

The models highlighted below were all highly significant ( p < 0.0001).

The highly significant p values ( p < 0.0001) showed that there was a significant change in mean value from baseline for all three variables.