“highly significant”

[ 99m Tc] TcO4 − (Pertechnetate) A highly significant effect of both the cell line and radioactivity concentration on cellular DNA fragmentation was observed (two-way ANOVA: p < 0.0001 for both factors), indicating that chemoresistance correlates with radioresistance.

We log-transformed circulating DAAM2 mRNA expression, demonstrating a highly significant increase (p < 0.0001) in circulating DAAM2 mRNA in pregnancies complicated by preterm fetal growth restriction (Fig. 1 a) compared to gestation-matched controls.

Differences were considered significant when p<0.01 (*), and highly significant when p<0.0001 (***).

All in all, a comparison of ALDH1+ with ALDH1− cells sorted from primary, early, and late MRT xenografts demonstrated a highly significant tumor-initiation potential (p < 0.0001; 19/21 injections of ALDH1+ cells formed tumors in comparison with 2/21 injections of ALDH1− cells).

Among both British and Scandinavian populations, LD-based estimates of effective population size were similar to census population sizes and showed a highly significant relationship ( F 1,33 = 37.12, p < 0.0001; Fig. 3 ; data are presented in Supplementary Table S8 ).

When performing a simple linear regression analysis of all PSA and CA19‐9 serum samples, it revealed a highly significant association ( R 2 = 0.938, p < 0.0001; Figure 3B ).

There was a highly significant difference between the sizes of eggs of female 1 (1.000 ± 0.083 mg) and female 3 (t = -3.84; p = 0.0001).

The high variability between the lines was confirmed by highly significant values for the F test (F-value equal to 2.3 and 12.6, P < 0.0001 to ALS and PWM, respectively), for all genotypes, supporting the hypothesis that the AS population is representative for mapping resistance loci .

A statistically highly significant enrichment ( p < 0.0001) of very stable interactions when using an approximate energy model [ 19 ] to match native miR sequences with the near-splice site miR:RNA and miR:DNA interactions was observed, showing much stronger and more significant enrichments for miR:DNA interactions (Figure 6 ).

* indicates p‐value 0.01 to 0.05 (significant) ** indicates p‐value 0.001 to 0.01 (very significant) *** indicates p < 0.001 (highly significant) **** indicates p < 0.0001 (extremely significant) 4.14.

During SMC differentiation of A404 cells, 72 (55.4%) of these genes showed significant differential regulation, pathway over-representation that was highly significant by Fisher's Exact Test (p<0.0001).

boulardii CW extract was highly significant in all groups, except the group with 2.5 mg/mL concentration ( P <0.0001).

This analysis reproduced the highly significant effect of synchrony (F 1,145.96 = 34.9, p < 0.0001) already found in the 2 × 2 type B model.

Intriguingly, the sorted IFNβ + Tip-DCs also stimulated the naïve T cells to proliferate in a highly significant manner (p < 0.0001 as compared to macrophages) and more efficiently than the sorted IFNβ/YFP − bona fide Tip-DCs ( Figure 6 ).

It is also plausible that these inconsistent results are due to the relatively small sample size in MRI studies, as a related clinical study from TREND with a much larger sample size ( N = 661) revealed a highly significant and slightly stronger correlation between TMT B-A and DT gait speed while subtracting ( p < 0.0001, r = 0.27) ( Hobert et al., 2017 ).

Co-infection analysis showed a highly significant association with HIV (p<0.0001, OR=26.32, 95% CI: 20.22-34.28).

There was a highly significant correlation ( p < 0.0001, correlation coefficient = 0.62) between the two scores.

According to t test, differences between the analyzed genotypes were highly significant ( p <0.0001).

Results Data on all decided agonistic interactions produced a highly significant linear dominance hierarchy (h' = 0.97, p = 0.0001; 10,000 matrix permutations).

The baseline AIS grade effect on the fraction of two-grade improvements in the STASCIS and the present study’s databases were both highly significant, p < 0.0001.

Comparative evaluation was done between Group I and Group II, Group I and control group, and Group II and control group, all showed highly significant difference ( P < 0.0001) [Tables 1 – 3 ].

Nevertheless, the reduction of phagosomal PtdIns4P was highly significant ( p < 0.0001; Figure 6F ), implying that PI4K2A is at least partly responsible for the reformation of PtdIns4P in late phagosomes.

The difference between the sta-1(RNAi) and akir-1(RNAi) animals is highly significant (p<0.0001; one-sided log rank test).

After four months, a highly significant difference was noted between the two groups (p-value <0.0001), implying that intralesional PRP therapy led to a far more significant decrease in the SALT score compared to topical minoxidil therapy.

The differences between baseline and each time point (12, 24, and 36 months) were highly significant (p < .0001), and the differences between the time intervals (12–24 months, 12–36 months, and 24–36 months) were also significant (p < .0001).