“highly significant”

Regarding HR ( Figure 4A ), a marked and highly significant decrease with age was observed during the first 12 months ( p < 0.0001; r = − 0.833), followed by a relative stabilization during adulthood characterized by a slight increase up to 120 months ( p < 0.0001; r = 0.084), and then another moderate increase between 120 and 220 months ( p < 0.0001; r = 0.300).

A highly significant in- crease in the number of tumors was ob- tained with the positive asbestos controls (p<0.0001) (Table 3).

There was a large and highly significant (p < 0.0001) increase in IL-8 mRNA at 2 h in response to TNFα in both control and PAH endothelial cells.

Differences were statistically significant when p < 0.05 (*) (#) and highly significant when p < 0.0001 (**) (##) versus each respective mock or KLF1 wild-type control group. 3.

This 1.65-fold gene enrichment is highly significant ( P < 10 − 4 ).

The proposed models for all responses were highly significant with values ranging from p < 0.0001 to p = 0.0005 (Table 2 ).

control, ceramic, ultrasonic, plastic, and amber, the differences were highly significant (P < 0.0001), with the same strong F-value pattern observed in the flea analysis ( Table 2 ).

The increase in the student performance was found to be very highly significant in group I after the lecture (p-value < 0.0001) (Figure 2 ) (Table 1 ).

The analysis of blood loss showed that the median (IQR) total blood loss was 575 mL (375, 875) in the NTA group compared to 450 mL (325, 675) in the TA group, a highly significant difference (p < 0.0001 Mann-Whitney test).

This is highly significant in both the linear and quadratic term ( p < .0001).

The number of patients experiencing exacerbations decreased only during treatment with mepolizumab, and in a statistically highly significant manner [odds ratio, 0.019; 95% confidence interval (CI), 0.001–0.320; hazard ratio p < 0.0001].

There were consistent and highly significant (p < 0.0001) reductions of blood pressure, fasting plasma glucose, abdominal obesity, triglycerides and an increase in HDL cholesterol after 9 months of treatment with Irbesartan monotherapy as well as with the combination therapy (for individual figures see table 3 ).

3 ], with a highly significant interspecific contrast (estimate=21.2×10 −4 , P <0.0001).

The SQUID is responsive, exhibiting highly significant (p < 0.0001) increases during a major QI initiative, and its internal consistency is excellent (Cronbach's alpha = 0.93).

More group patients had 3 or more process items met than control patients ( p = .0312), a difference remaining highly significant (with all p > .0001) with the cut point moved from 3 to 7, 8, 9, or 10 items.

This difference is highly significant (p = 0.0001), confirming the better tolerance of anticoagulant treatment with LMWH.

However, the same 19% survival advantage observed between Stage IIIA cases and Stage IIIC cases treated at SEER institutions was highly significant ( P < 0.0001) when a greater number of patients were included in both Stage III subgroups.

The earlier trial also found no difference in walking speed (effect size = 0.00 [−0.08, 0.08]) 9 , 11 but did report a highly significant increase ( P = .0001) in FAC score from a median of 1 (1-1) to 2 (1-2). 12 However, the earlier trial had a greater risk of potential bias than the one reported here for the following reasons: randomization was not to group but to the order of each individual using an AFO once the control walk (without AFO) had been made; observers were not masked to conditions because participants used the AFO during testing sessions; and an independent randomization service was not used.

The log-rank statistic which formally tests whether the Survival Curves for each group overlap was highly significant (χ 2 = 32.26 for >LLOQ and 29.99 for >200, p < 0.0001).

The coefficients of this model are highly significant ( p < 0.0001 for all variables; table 2 ) and the model is highly explanatory ( R 2 = 0.972).

Error bars indicate 95% confidence limits. and then by a second increase in MN-NCE levels at the end of the study. MN-PCE Levels Exposure to benzene by inhalation or by gavage in- duced a highly significant increase (p < 0.0001) in the fre- quency of MN-PCE detected in the peripheral blood of mice (Figs. 2 and 3; Table 2).

The percentage of children from urban area had more bleeding than that of rural area and it was highly significant ( P < 0.0001), and the percentage of children from rural area had more calculus than that of urban area and it was highly significant ( P < 0.0001) [ Table 2 ].

Moreover, a highly significant correlation was observed (r = 0.669, p < 0.0001) between pure tone average (PTA) thresholds at implant activation and those at the last follow-up, as analyzed using Pearson’s correlation coefficient.

The results revealed considerable heterogeneity ( I 2 = 80.93%, τ 2 = 0.1160), confirmed by a highly significant heterogeneity test ( Q (7) = 34.0977, p < 0.0001), indicating that variability across studies exceeded what would be expected from sampling error alone.

All three ratios showed highly significant power exponent β (β for ratio between systolic and diastolic SR long = −0.07±0.02, p<0.0001; β for ratio between systolic and diastolic SR circ = −0.06±0.01, p<0.0001; β for ratio between systolic and diastolic SR rad = −0.06±0.02, p<0.0001).