“highly significant”

Y 1 = 6.119 + 1.815 A - 4 .626B - 18 .608C + 0.436AB + 0.580AC - 0 .887BC - 0 .633A 2 + 3.269 B 2 + 15.650 C 2 Y 2 = 18.883 + 13.360 A + 49.779B - 186 .192C - 9 .063AB + 7.010AC - 24 .790BC - 3 .289A 2 - 13.194 B 2 + 150.865 C 2 The yield model (Y 1 ) had an F-value of 105.270, indicating highly significant level differences ( p < 0.0001).

The mortality was not significantly different between patients with and without complications ( P = 0.52), while there was a highly significant difference in LOS between subjects with and without complications (median, 6 versus 18 days, respectively, P < 0.0001).

ANOSIM analysis confirmed a highly significant difference among the four microbial community structures ( R = 0.81; P = 0.0001) and the performed test showed significant differences in the pairwise comparisons of the sites with R values approaching 1 in most of the cases ( Table 3 ).

By one-way ANOVA, there was a highly significant disturbance category effect ( F = 44.7, p < 0.0001) with all three categories significantly different from one another ( p < 0.0001).

From 4 h to 24 h, the cubic components were highly significant (R 2 = 0.985–0.990; p < 0.0001), with significant quadratic components from 4 h onwards ( p = 0.001–0.003).

The association between poor quality of sleep and the other outcome variables of mental health (depression, anxiety, and stress) was highly significant (p<0.0001).

This association also remains highly significant in separate analyses of recurrent and nonrecurrent chromosome abnormalities as well as of specific subtypes of cancer ( P < 0.0001 for all comparisons).

sclerotiorum populations from the four different countries with the R ST fixation index statistic highly significant ( P < 0.0001) for pairwise combinations of England/Norway ( R ST = 0.094), England/Australia ( R ST = 0.186), Scotland/Norway ( R ST = 0.068), Scotland/Australia ( R ST = 0.152), and Norway/Australia ( R ST = 0.198).

Whereas phagocytosis in the presence of heat-inactivated serum from NHD showed no significant association with LPC concentrations (not shown), a highly significant negative correlation ( r = –0.556, p < 0.0001) between LPC levels and phagocytosis in case of heat-inactivated serum from patients with SLE was observed (Figure 5 B).

The difference in DOC between the vaccinated and unvaccinated groups was highly significant prior to DOC matching (Student’s t , p < 0.0001).

With all three stimulation probes, despite the difference in design, a highly significant lowering in blood pressure was achieved with a p = 0.0001 according to the Wilcoxin Signed-Rank test.

The Egger’s test result was highly significant (t = 6.60, p < 0.0001), indicating potential asymmetry and suggesting the likelihood of publication bias ( Supplementary File S26 ). - Similarly, in the OS multivariate analysis, the funnel plot showed some studies lying outside the triangular area, consistent with significant heterogeneity.

Triglyceride, HDL-C and Atherogenic index of plasma There was a highly significant reduction in TG from 261.11 ± 74.13 mg/dl (baseline) to 171.94 ± 86.51 mg/dl (visit 5) in the amla extract group ( p < 0.0001 within the group), whereas the TG reduction in the placebo group was from 247.62 ± 57.70 mg/dl to 210.47 ± 65.27 mg/dl (Fig. 3 a).

Similarly, for studies evaluating serum TNF-α levels, visual inspection of the funnel plot also revealed asymmetry ( Figure 4 B), which was confirmed by the highly significant results of Egger’s test for publication bias ( p < 0.0001).

The logistic regression model showed orographic lift to be a highly significant predictor of the probability of low altitude soaring (Wald test, p < 0.0001).

During the dark phase of the dark/light cycle these differences were highly significant (all p < 0.0001) indicating that the states of vigilance in older mice were less consolidated compared to young mice.

Furthermore, quantification revealed a highly significant ( P = 0.0001) fourfold reduction in the average number of Kyn + cells in D-1MT–treated animals ( Fig. 3 B ).

We mapped ∼54 million sequencing tags to the reference human genome (alignment details are presented in Supplementary Table S9 ) resulting in a highly significant correlation (Spearman correlation = 0.77, P < 0.0001) between the RPKM values and the microarray generated expression values ( Figure 6 C).

The other seven genes, WD repeat-containing protein 61 , Dt1 , MADS-box protein , two genes of two-component response regulator -like genes, FT2a , and PhyB , showed highly significant association with flowering time ( P < 0.0001) ( Table 3 and Supplementary Table S8 ).

Significant changes were observed across all the global spatio-temporal parameters studied: Cadence (steps/min): a highly significant improvement in cadence was noted ( p < 0.0001), indicating that the intervention had a substantial effect on step frequency; Speed (m/s): walking speed also showed a significant increase ( p < 0.0001), reflecting enhanced movement efficiency; Stride length (m): significant changes in stride length ( p < 0.0001) were identified, suggesting modifications in gait mechanics over the intervention period.

Gene set enrichment analysis identified a highly significant overlap of transcriptional markers of intestinal stem cells (chi‐squared test with Yates's correction, P < 0.0001; Munoz et al , 2012 ) between the gene lists, demonstrating elevated expression of some members of the intestinal stem cell signature following Huwe1 deletion.

As shown in Figure 4 , the diagnostic power of C6Ma1 and C6Ma3 was highly significant with an AUROC of 0.90 ( P < .0001) and of 0.87 ( P < .0001), respectively when comparing healthy control to patients with cancer.

We observed a highly significant correlation between both assays (r = 0.78, p<0.0001, Fig 2D ), indicating that HIV-Flow and mRNA Flow FISH provide similar estimates of the size of the translation competent reservoir in clinical samples.

The highly significant positive phenotypic correlation between NCPP and SPP ( r = 0.90, p < 0.0001) and the negative correlation between those traits and TSW ( Table S4 ), may indicate compensation between yield components via morphological modifications [ 7 ].

Statistical analysis using Student’s t-test revealed highly significant differences in Fas (P < 0.0001) and RIPK1 (P < 0.05) expression between EMs and normal endometrial tissues.