“highly significant”

Under semi-field experimental conditions, differences between wall type and percent mortality from time of initial application to end of observation was highly significant ( p < 0.0001), while no differences were seen in final mortality between the two doses ( p = 0.148).

Moreover, the study revealed a highly significant correlation between SNOT-12 and SNOT-22 ( P = .0001).

Overall, the presence of this fusion transcript represents a highly significant novel association with the SHIP1-deficient phenotype, with a conservatively estimated odds ratio (OR) of 153.0 (95% CI: 5.562–4209, P < 0.0001) compared to the healthy 13 controls, and an OR of 606.3 (95% CI: 22.76–16,150, P < 0.0001) compared to all available SHIP1-sufficient IBD and healthy control subjects ( n = 53).

These data indicate overall higher sST2 concentrations in males than females, which is highly significant after adjusting for age (effect estimate 49% lower in women [95% CI 42% to 55%], p<0.0001) ( Table 1 ).

Strong and highly significant negative mean intrinsic correlations were found between SENT_CORE and SENT_MEM ( R = − 0.27; 92.03% of the participants showed a negative correlation, p < 10 −4 ), and a positive correlation was present between SENT_MEM and SENT_VISU ( R = 0.058, 62.32% of the participants showed a positive correlation, p = 0.0024), while there was no significant correlation between SENT_CORE and SENT_VISU ( R = − 0.037; 56.52% of the participants showed a positive correlation, p = 0.074).

In the overall analysis of patients who received MPS and IVMP, there was a highly significant difference (3.9 ± 1 vs. 2.4 ± 1 p < 0.0001).

An unpaired t-test showed the difference to be highly significant p < 0.0001.

However, the difference in FF was statistically highly significant ( p <0.0001) even on multivariate analysis adjusted for BMI and PAPP-A levels, indicating that ART was almost certainly an independent predictor of low FF.

The genetic indices based solely on the frequency of the allele MGE7 243 and on the homozygous genotype MGE7 243/243 were strongly associated minSAL, and the models were statistically highly significant ( p < .0001).

Differences comparing MT/MT with WT/WT and WT/WT with Het are highly significant ( p < 0.0001).

Mann–Whitney U test revealed that 11 of 13 phyla (except Actinobacteriota and Nitrospirota) showed highly significant differences between rhizosphere and bulk soils ( Table S2 : **** p < 0.0001).

The differences among groups were highly significant at each time point ( p < 0.0001).

The proportional reductions in recurrence with dose-intense chemotherapy were similar and highly significant (p<0·0001) in oestrogen receptor (ER)-positive and ER-negative disease and did not differ significantly by other patient or tumour characteristics.

In the comparison between SAMS patients and the control group, we observed a significant difference ( P < 0.05) in BUN, fasting blood glucose, and triglycerides and a highly significant difference in total cholesterol, creatinine, CPK, CRP, and 25OH-vitamin D serum levels ( P < 0.0001) (Tables 2 and 3 ).

The LOD scores obtained for the QTL in both families were highly significant ( p < 0.0001).

The Top ICH genes had highly significant and similar associations within the primary cluster that included intratumoral densities of CD45 + (r = 0.53–0.67, all p < 0.0001), CD8 + T cells (r = 0.48–0.71, all p < 0.0001, Fig. 3 B), CD20 + B cells (r = 0.47–0.56, all p < 0.0001), and CD138 + cells (0.37–0.5, all p < 0.0001, Additional file 1 : Table S1).

In the full sample (ages 40–75), the first-stage Kleibergen–Paap rk Wald F is ≈9.16 (borderline strength), yet the Anderson–Rubin and Stock–Wright weak-IV-robust tests are highly significant (p≈0.0001), indicating a positive effect of retirement on depressive symptoms under weak-IV-robust inference.

There was no significant correlation between either of the PTH assays and 25(OH)D concentrations in HD patients, but we found a highly significant (P < 0.0001) correlation ( ρ = 0.766) between bAP levels and both PTH assays and between 25(OH)D and 1,25(OH) 2 D levels ( ρ = 0.522).

The prevalent downward bias of the cystatin C-based eGFR (CAPA) compared to the CKD-EPI-derived eGFR (−21.35 ± 18.64 and −13.50 ± 18.31% for males and females, respectively) was highly significant ( p < 0.0001).

1 ), being the difference with the WT variability highly significant (Wilcoxon signed rank test V = 12246, P < 0.0001).

Considering all five species, the difference between the years is highly significant for O. kevoensis (χ 2 = 69.5, P < 0.0001), whereas in O. inclinans the difference is only marginally so (χ 2 = 4.6, P = 0.03).

There was a highly significant treatment × week interaction on the number of floor eggs produced (F(11,466) = 3.75, p < 0.0001), suggesting that the effect of treatment differed across weeks, and the LSMeans and Standard error for treatment × week interaction are reported in Table 3 and Figure 9 .

The overall significance of sex in this model was found to be highly significant ( p < 0.0001) for all three populations using the log-likelihood test.

This difference was highly significant, t(70.14) = 4.04, p = .0001 (degrees of freedom using Satterthwaite’s correction for unequal variance).

The PPE59-IgA medians in pTB sera were highly significant compared to those of ORD/HD (p < 0.0001).