“highly significant”

The authors highlighted that the use of IR screening has proven to be reliable in distinguishing between an allergic and an irritant reaction in the diagnosis of contact dermatitis (ACD), given that the difference in average temperature between the two groups was found to be highly significant (p < 0.0001).

The estimated variance components for genotype were highly significant (P<0.0001) at both seedling and adult plant stages ( Table 1 ).

Likewise, rFVIIa at 6.75 μg/mL produced a highly significant increase ( p < 0.0001), further supporting its strong procoagulant effect under these assay conditions.

This model identified 105 HMMs as significant distinguishers at P = 0.05, and 42 of them exhibited highly significant differential abundance between the two groups (unpaired t -test, FDR-adjusted P < 0.0001).

The use of mifepristone showed a reduction in the use of oxytocin (RR = 0.84; 95% CI: 0.70–1.01), although this difference did not reach statistical significance ( p = 0.065), and a highly significant reduction in prostaglandin use (42.7% vs. 78.9%; RR = 0.54; 95% CI: 0.48–0.60; p < 0.0001), with no significant difference in cesarean section rate (18.9% vs. 23.6%; RR = 0.80; 95% CI: 0.63–1.01; p = 0.068).

A highly significant correlation between CNP and TNF-α (p<0.0001) was detected in cardiac tissue ( Fig. 6 ).

The equation developed through the regression is as follows: Percent cover of ISA = 0.0795 (radiance) + 0.00868 (population count) The regression had an r 2 squared of 0.59 and is highly significant p <.0001.

A highly significant correlation was found between NIHSS and FIM ( p < 0.0001), confirming that NIHSS scores are a good predictor of stroke disability in terms of FIM and functional gain. 50 One study also found that there was a significant association between NIHSS and upper extremity impairment and stroke severity. 51 This may explain why there was a significant correlation between NIHSS and ARAT scores for assessing arm function in stroke patients in the present study.

Supplementary data bmjopen-2023-077508supp001.pdf Regression model The logistic regression model was statistically highly significant (p<0.0001).

Highly significant differences have been found between ethnic groups in the total carrier frequency of pathogenic CFTR variants (χ 2 = 23.86; p = 0.0001) as well as in the total carrier frequency of heterozygotes (ꭓ 2 = 11.82; p = 0.003) and polymorphisms (χ 2 = 10.43; p = 0.005).

This study did not show a benefit in OS (adjusted HR 0.78, 95% CI.0.56–1.08; P = 0.13), but did reveal a highly significant improvement in PFS, with 5 year PFS of 47.6 vs. 31.8% for those given immediate adjuvant chemotherapy (HR: 0.54, 95% CI: 0.40–0.73, P < 0.0001).

Quantitative analysis revealed that rhabdospheres had a higher number of acidic vesicles ( Figure 3B , top) and a highly significant lower vesicular pH compared to native RD cells ( Figure 3B , bottom; p<0.0001).

There was a highly significant differ- ence between p43-positive lymphocytes in patients with malignant lesions and those in benign breast tissues (P < 0.0001) (Figure 1).

However, the comparison of the overall chemical profiles, via discriminant analysis, of Nosema -infected bees and their control counterparts at days 5 and 10 showed highly significant differences for each colony (Colony 98: Wilks’ λ = 0.015, F 39,92 = 7.39, p < 0.0001; Colony 120: Wilks’ λ = 0.011, F 39,.95 = 8.73, p < 0.0001; Colony 231: Wilks’ λ = 0.037, F 27,102 = 7.92, p < 0.0001; Figure 1 ).

These revealed that the difference in mean activity between winners and losers was highly significant in the case of strong dominance pairs (W = 0.39; L = 0.20; Mann–Whitney U = 1, df 23, P < 0.0001).

Moreover, 8 classes, including CE, CER, DAG, FFA, LPC, PC, SM, and TAG, showed highly significant differentiation with p -values < 0.0001 ( Table 1 ).

In this group, the probability of concealment was 0.647; in the remainder it was 0.353, which was a highly significant difference ( P <0.0001).

Upon co-inoculation, the phosphatase activity was enhanced and highly significant ( p -value < 0.0001), with a nearly 3-fold increase in the accumulation of phosphate ( Figure 2 ). 3.4.

However, even if the strict Bonferroni correction had been applied for the 3 variables, all the relevant p -values would still have been highly significant as they are mostly p < 0.0001.

In addition, the difference between the IC 50 values of daucosterol in breast cancer and noncancerous cells was found to be statistically highly significant ( p < 0.0001) and the difference between the IC 50 values in both cell lines was found to be statistically highly significant ( p < 0.0001) ( Figure S23 ). 3.

Average heights have been increasing over the past few decades in several transitioning Asian populations, 17,24 probably as a result of improving childhood nutrition and health, 32 Few data are available for Thailand but, amongst the female TCS participants ( n = 47,314), the youngest group of women (15–19yrs) are on average 3 centimetres taller than the oldest group of women (50+yrs) and there is a highly significant trend of increasing height with decreasing age ( p < 0.0001).

This demonstrated that the lipolysis/plasma lipid relationships were still highly significant ( P <0.0001) after correction for sex; age; body mass index; waist circumference; waist-to-hip ratio; nicotine use; treatment of type 2 diabetes mellitus, hypertension, or hyperlipidemia; and fat cell size.

IHC H‐scores (Figure 4D ) revealed a highly significant difference between WT and Vasn −/− mice ( p < 0.0001).

Highly significant correlations generally exist between the various markers (p<0.0001), with a slightly lesser significance between MLANA and MITF (p = 0.005), with the exception being between MLANA and TYR markers, where no statistical significance was found (p = 0.11).

All 28 possible lane/read pair combinations produced highly significant P -values based on 10 000 Monte Carlo iterations ( P <0.0001; Bonferroni-adjusted α 0.01 =0.0004).