“highly significant”

The difference between both conditions, however, proves to be highly significant ( p < 0.0001) with a higher average correlation length in the presence of fluid shear stress of 33.3 μm, compared to 24.1 μm in the case of no fluid flow.

The resulting M-DLR Score demonstrated a highly significant difference between the G1 and G2/G3 tumor groups across all datasets ( p < 0.0001) (Fig. 3D ).

Importantly, when we analysed half-life across all infections (treated and untreated), there was a highly significant interaction between the effect of drug treatment and parasite genotype ( = 9.10, P < 0.0001; compare Fig. 2 B,C; Table S1.5 ), as well as significant negative correlations with pre-peak growth rate and parasite density at peak (which were independent of differences between parasite lines) (intrinsic growth rate = 4.15, P = 0.049; density at peak = 9.48, P < 0.005; Table S1.5 ).

Statistical analyses revealed highly significant differences between infected groups sampled at 12 h and 96 h for both genes ( p < 0.0001).

Level of correlation between IHI and PNGIMR on KD60 and M24 in WHO cone bioassays Correlation between IHI and PNGIMR results was statistically highly significant but with a stronger association between M24 results (r = 0.9, p < 0.0001, n = 20) than between KD60 results (r = 0.6, p = 0.002, n = 20) (Fig. 3 ).

Eleven of these were within-serogroup switches, representing a highly significant ( p < 0.0001) enrichment based on the observed serotype distribution.

The MANOVA test (Table 2A ) yields a highly significant p-value for both the 2 independent variables (p < 10 -4 ).

This difference was statistically highly significant (p<0.0001), a similar situation being recorded also for the mean scores of the PSS (p<0.0001) (Table 4 ).

For the concentration of IL-5, the omnibus test was highly significant (Kruskal-Wallis, χ2 3 = 30.59, p < 0.0001), and the pairwise comparisons showed that non-infected mice had lower levels of IL-5 compared to all infected groups ( Fig 3a ).

( 0.0001 ) 0.38 ( 0.0004 ) − 0.02 ( 0.8372 ) − 0.16 ( 0.0829 ) − 0.31 ( 0.0001 ) ) ( a t − 3 c t − 3 p t − 3 r t − 3 ) The Portmanteau test for cross correlation of residuals, Durbin Watson tests, and the univariate model AR diagnostics were non-significant, while the R-squared for each series was highly significant (ranged from 0.44 to 0.87, p < 0.0001).

A highly significant (p < 0.0001) reduction in Fn/c was observed between GFP-Vpr 1–96 (Fn/c ~2.4) and GFP-Vpr A6-2 (Fn/c ~0.9) indicating a reduction in nuclear accumulation.

Monte Carlo repeated random sampling indicated that the restriction of V2 apex bNAb elicitation to five SHIVs was highly significant ( P < 0.0001, see Supplementary Methods ).

The difference in heme levels between the Sham group and the ischemic core region was highly significant (P < 0.0001) ( Fig. 2 d).

ANOVA results revealed a significant ( p < 0.0005) and highly significant ( p < 0.0001) difference in genotypes and B toxicity treatment ( Table 2 ). 3.4.

Two-way ANOVA revealed highly significant main effects for both analgesic group (F = 503.44, p < 0.0001, ****, η 2 = 0.329) and surgery type (F = 329.15, p < 0.0001, ****, η 2 = 0.430), as well as a significant interaction effect (F = 41.06, p < 0.0001, ****, η 2 = 0.215).

Discrimination followed the order IL‐2 > IL‐13 > IFN‐γ with, however, only subtle differences in the respective highly significant AUC (0.9310, 0.8994, 0.8316) values (all p < .0001; Figure S7 A), which was similar to the results obtained with gradient‐purified PBMC with regard to IL‐13 and IFN‐γ while IL‐2 levels were clearly lower and less discriminatory after 6 days (Figure S4 A).

The p -values indicated highly significant differences ( p < 0.0001) between the control and mixes 3−7 for anaerobic runs, and between the control and mixes 2−7 for aerobic runs.

There was also a positive correlation between utrophin and β-DG levels in muscle fibres of DMD P11 (Spearman’s, r 2 = 0.75) and P12 (Pearson’s, r 2 = 0.45), both of which were highly significant (p<0.0001; Fig 4c and 4d ).

Results Relationship between Maternal LOC and IQ at 8 The unadjusted difference between the mean IQ of 8-year-old children whose mothers were external compared to those who were internally oriented showed deficits of 7.33, 5.29, and 7.23 IQ points for the verbal, performance and full IQ scales, respectively ( Table 2 ); each was highly significant ( P < 0.0001).

Third, analysis of the tumor specific variants in BCL2 regions from FL specimens, at both high (≥15%) and low (≤1%) frequencies identified a consistent and highly significant bias towards the AID mutation patterns expected to be found in aSHM (see Additional file 4 : Figure AF1: WRCY motif P <0.0001, WA/TW motif P <0.0012 by one-tailed Fisher’s exact test [ 36 ]), strongly indicating that the identified variants at both high and low frequencies are due to a common biological process and are not a computational artifact.

Additionally, OncomineTM showed a consistently higher total mutation count compared to CCLE ( Figure 4 B), with differences that were highly significant ( p < 0.0001), underscoring methodological differences in mutation calling.

A generalized additive model (GAM) fitted to the normalized data revealed strong non-linear temporal structure in activity under all light treatments, with highly significant treatment-specific smooths of time (all F > 380, all p < 0.0001), explaining 97.6% of the variance in normalised activity (adjusted R 2 = 0.97).

Considering the gingival scores, a statistically highly significant reduction in groups taking cholecalciferol supplementation (p<0.0001) on subsequent visits depending on the dosage, while statistically insignificant results were seen in the placebo-consuming folk (Table 3 ).

The difference between PBS and fixed samples (formalin and PAXgene) was highly significant (p < 0.0001) but also between PAXgene and formalin (p < 0.05).

As shown in Supplementary Table S3 , A (Time) were significant ( p = 0.0018); B (Temperature) and C (Kinds of acid) was highly significant ( p < 0.0001).