“highly significant”

By contrast, there was a highly significant and strong effect of species ( R 2 = 0.5048, p < 0.0001), with pairwise tests indicating cranial shape differences between 16 of the 45 pairwise comparisons ( table 2 ).

Compared to the manual approach of biometric data export and intraocular lens calculation (76.7 ± 12.3 s) as well as the manual export of the reference image to a portable external storage device (26.8 ± 5.5 s), a highly significant saving of time was achieved ( p < 0.0001).

The model showed a highly significant value (p < 0.0001) (Table 3 ).

Tukey’s multiple comparison test showed highly significant differences between the control and remission groups ( p < 0.0001), the control and active phase groups ( p < 0.0001), as well as between the remission and active phase groups ( p < 0.0001).

The mean gait score was 22.12 in the bipolar prosthesis group in comparison to 26.55 in the THR group and was highly significant (p value< 0.0001).

A highly significant variation ( P < 0.0001) among the genotypes for both WSC accumulation and remobilization per GDD was found in all environments.

In addition, there were highly significant correlations in the immunostaining scores between these two paired sets ( r >0.90 and P <0.0001, for each protein).

Other Clinical Efficacy Results The mean changes from baseline in the IKDC subjective score, which ranges from 0 (worst result) to 100 (best result), were highly significant at all time points (i.e., P < 0.0001; including Month 3) and increased in their extent through Month 24 (LS mean increase from baseline: 41.6 ± 1.9 points; 95% CI: 37.9-45.4).

Quantitative real-time polymerase chain reaction revealed a highly significant downregulation of MDM4 mRNA in tumor tissue compared to control tissue ( P < 0.0001), a finding confirmed by western blot on a subset of 20 tissue pairs.

However, the corresponding global F ST was highly significant ( p < .0001), and its 95% confidence interval (CI) did not include 0 (0.00435–0.00828), indicating the presence of genetic structuring across the study area.

On the SCQ, the right lateral region showed a highly significant ( χ 2 = 21.82, p < 0.0001) age-by-region interaction.

However, the addition of 100 mM KCl had a much greater (a 12-fold increase), highly significant ( p < 0.0001, two-sample t -test, N = 4 and N = 2 for 0 and 100 mM KCl, respectively, Fig. 3 A ) effect on the K d for the D3402A mutant MTBDs than WT MTBDs.

(2022) found no significant differences in input resistance and spike width between Calb2 and Chrna2 cells, whereas we found highly significant differences in these parameters ( p < 0.0001 and p = 0.01, respectively, in pairwise comparisons), and also in the initial firing frequency and adaptation ratio (Extended Data Fig. 9-1 ).

In both species, none of the randomly generated gene sets reached or exceeded these observed proportions, resulting in highly significant outcomes (Figure S15 ) (permutation test, empirical P < 0.0001).

The quadratic model for TS was found to be highly significant (F-value = 31.08; p < 0.0001), with a coefficient of determination R 2 of 0.9756.

When hair follicle harvested from lower occipital donor area of Group ’A’ and Group ’B’ patients were compared and we observed highly significant statistical difference between these two groups (df = 10, t = 18.77, P < 0.0001) [ Table 2 ] Average FTR from total scalp donor area in Group ’A’ and Group ’B’ patients was 5.10 and 3.10, respectively [ Table 4 ].

Based on the matched pairs analysis ( Table 3 ), the overall mean difference of −6.4 showed that the facility mean was less than the OTSC mean, and this difference was highly significant (p-value <0.0001).

The difference with respect to flares occurring at a longer time distance from an attack was highly significant ( p < 0.0001).

A highly significant correlation was observed between nuclear matrix protein level and 8-OHdG, highest in SA for BLCA-4 ( R = 0.583, p = 0.0001) ( Table 6 ).

Individually, HiFiCas9 treatment had a highly significant impact on viability (F (1, 12) = 69.55, p < 0.0001), accounting for 72.96% of the total variance.

Transfer of CD4 + CD25 + T cells resulted in a highly significant amelioration of EAE signs (ANOVA: P < 0.0001).

➣ Subgrouping of vaccinated cases according to used vaccine revealed three groups: Group 1: Pts received viral vector-based vaccines with adverse events Group 2: Pts received mRNA-based vaccines with adverse events Group 3: Pts received inactivated virus vaccines with adverse events Comparing each two groups as regards adverse events done and revealed the following results Comparing group 1 to group 2 Viral vector-based vaccine group (group 1) showed highly significant increase in cases of thrombotic thrombocytopenic purpura/cerebral venous thrombosis/pulmonary embolism with p < 0.0001 In the same context, group 1 had statistically significant increase in cases of DIC ( P = 0.0316), GBS ( P = 0.0036) and ATM ( P = 0.0089).

While PET/CT was performed significantly more often in small PAs (P<0.01), it showed highly significant superiority over the other imaging modalities in accurate preoperative localization in both small (P<0.0001) and large PAs (P<0.01).

There was a highly significant difference in the serum Ki-67 concentrations between healthy dogs and dogs with non-neoplastic diseases ( p < 0.0001, Figure 2 ).

The difference was statistically highly significant ( P < 0.0001; log‐rank test).