“highly significant”

When the combined group of 8 patients with hypercalcaemia is compared with the control group the difference is statistically highly significant (Mann Whitney, U Test P=0.0001).

The activity of AMPs and Tobramycin against preformed biofilms resulted to be similar in 5 out of 6 strains tested, causing a highly significant reduction of biofilm viability compared to the controls (biofilm not exposed; p < 0.0001), regardless of the concentrations tested (Figure 3 ).

While pairing at this locus was abolished throughout the gonad in the hal-2 single mutant, the syp-3; hal-2 double mutant exhibited a highly significant increase in pairing over the hal-2 single mutant specifically in Zone 2 (p<0.0001), the same zone in which chromosome V PCs were shown to be active in the hal-2; syp-2 double mutant.

The models were highly significant (p<0.0001) with a non-significant lack of fit (p=0.2729 and 0.1283, respectively).

In contrast, native jugular veins showed a clear, dose-dependent relaxation, reaching highly significant differences at the maximal concentration ( p < 0.0001 vs. all graft groups; Fig. 2 A).

Findings Both the number of metastases and metastatic clusters had a highly significant impact on OS (p < 0.0001, p = 0.003 respectively).

By comparison, the two missense variants reported here were predicted to be substantially more destabilizing, and this difference was highly significant ( P < 0.0001, Student t-test).

The results are statistically highly significant WOMAC osteoarthritis index at V1: (4.24 ± 1.94/6.19 ± 1.79; p < 0.0001, t test and Wilcoxon test), not significant at V2: p = 0.1636, highly significant at V3: p = 0.0009, and significant at V4: p = 0.0123 (Fig. 4 ).

Most notably, this includes YAP and TEAD1, with YAP's regulatory role most significantly determined in the mesothelioma cell line, NCI‐H2052 (top two p‐ values, each < .0001) and TEAD1 also yielding a highly significant association ( p < .0001) in the MSTO mesothelioma line.

Modeling and evaluation of LSA and iso-LSA yield responses ANOVA revealed that all models were highly significant ( p < 0.0001).

In addition, the difference between the BA.1 and BA.2 variants was statistically highly significant ( p < 0.0001).

The presence of viable hyphae and fruiting bodies in pre-therapeutic samples when compared to that of post-therapeutic samples was found to be highly significant with a P value of < 0.0001 and < 0.004, respectively.

The genetic indices based solely on the frequency of the allele MGE7 243 and on the homozygous genotype MGE7 243/243 were strongly associated minSAL, and the models were statistically highly significant ( p < .0001).

Directional asymmetry was large and statistically highly significant (p < 0.0001) for both shape (F above 55) and size (F above 92), prompting us to analyze separately the right valve (RV) and the left valve (LV).

There was a non-significant value of lack of fit found in the statistical analyses ( p > 0.05), and a highly significant level of performance of the model measured at the parameter level ( p < 0.0001), which indicates that the mode is capable of being accurately predicted by the variation of the parameters (Prajapati et al. 2021 ).

A highly significant difference was observed in relation to D5 to D6 implantated embryos (12.67±1.37 versus 19.86±1.89, p <0.0001) and in relation to D5 to D6 not implantated (12.76±1.17 versus 19.79±2.17, p <0001).

The LOD scores obtained for the QTL in both families were highly significant ( p < 0.0001).

Effects of the Experimental Conditions on Salivary Cortisol The two-factor (Time x Group) between-design repeated ANOVA showed a significant interaction effect of Time x Group, F (2.07, 57.96) = 8.28, p = 0.001, and a main effect of Time, F (2.07, 57.96) = 8.82, p<0.0001, and, as expected, a highly significant effect of Group, F (1, 28) = 91.08, p<0.0001.

The differences in velocities pre- and postinjec- tion were highly significant on a statistical basis (P < 0.0001).

A repeated-measures ANOVA showed a highly significant effect of drug condition ( F (3,21) = 20.3, P < 0.0001).

The mean change from baseline was 0.97 ± 0.40 to 0.39 across all follow-ups with a highly significant P- value of < 0.0001, indicating a sustained and statistically significant enhancement in contrast sensitivity over the 12 months [ Fig. 2 ].

Nonparametric tests for correlation confirmed that the negative relationship between log e -transformed deviations and population size was highly significant (Spearman rank-order correlation: ρ = −0.23, p < 0.0001; Kendall's τ: ρ = −0.17, p < 0.0001; N = 342).

NM_011979 ) showed a highly significant (P < 0.0001) 12-fold difference in mRNA expression level between A/J and AcB55 (AcB55 > A/J; Fig. 2 , boxed area).

Indeed, a highly significant ( p < 0.0001) diagnosis × location interaction (i.e., the closer to ThioS+ plaques from AD donors the higher the MAO-B area fraction versus no change in MAO-B area fraction with distance to sham plaques in CTRL donors) supports this interpretation.

Despite highly significant differences ( P < 0.0001) were noted for each property of fragments generated by two different fragmentation tools, the properties of MacFrag fragments are distributed in lower regions.