“highly significant”

When all species are considered there is a highly significant correlation between the mean number of binding sites per protein and biological complexity (r = 0.7000, P < 0.0001; Figure 4a ).

The global F ST / R ST value at 0.34/0.64 was highly significant ( P < 0.0001), signaling a substantive genetic differentiation among the populations as a whole, and most of the pairwise comparisons displayed a pronounced level of genetic differences (> 0.25).

When these numbers were analyzed, the statistic for the pooled data was not significant (G P = 0.05, 1 df, P = 0.8307), but the heterogeneity statistic was highly significant (G H = 39.2, 9 df, P < 0.0001), as was the total statistic (G T = 39.2, 10 df, P < 0.0001).

The association between up-regulation of CYP17A1 mRNA expression and DDTs concentration in sampled livers was highly significant (p < 0.0001).

Changes in expression levels of A.peg-1 appeared to be highly significant ( p < 0.0001) among the three distinct temperature exposure conditions chosen by analysis of variance (ANOVA) test ( Table 2 ).

Upon review of the unblinded data, the independent data monitoring committee observed a highly significant improvement in the primary endpoint ( p < 0.0001), along with favourable trends across multiple secondary endpoints, and recommended stopping the study in October 2023.

The overall multivariate log-rank test was highly significant (chi-squared = 71.16, p < 0.0001), confirming significant differences in conversion-free survival across dose groups.

For example, Fig 5 shows one example of a highly significant relationship between the date and phi (β = 1.779, p<0.0001).

Hematology The GD0 group exhibited a highly significant ( p < 0.0001) increase in Hb levels, with a change of 3.70% compared to the control.

Across the 2 h testing period there was a highly significant genotype by time bin effect ( F = 5.88; p<0.0001 ; Fig. 3D ).

The high heritability of SNS facilitated the identification of a highly significant and consistent association ( P < 0.0001) between this trait and SNP marker IWA5912 on chromosome arm 7AL in the five field trials where the spring wheat panel was evaluated (Zhang et al. 2018 ).

The Phase effect was highly significant [ F (3, 12) = 42.1, p < 0.0001] simply reflecting the fact that the different phase have different durations.

The results showed a highly significant difference in MOIs among the five groups (HC group and model groups at different lesion stages) ( F (4, 29) = 209.3, p < 0.0001).

The correlation was moderately strong (r = -0.6566) and highly significant (p < 0.0001).

All groups, except angiosarcoma (p value = 0.386), retained a highly significant increase of serum DR6 compared to normal controls (p values<.0001–0.0044).

In this analysis, group differences in subjective pain scores were highly significant before controlling for the effect of anterior cingulate cortex activation ( F = 38.0, P <0.0001); a finding that was reversed ( F = 1.8, P = 0.195) when removing (regressing out) this effect.

Modeling and evaluation of LSA and iso-LSA yield responses ANOVA revealed that all models were highly significant ( p < 0.0001).

Highly significant differences were observed in pairwise comparisons of Polled compared with Tianzhu, Gannan, Datong and Plateau yak ( p < 0.0001) and with non-significant differences were found between the Datong and Gannan yak breeds ( p < 0.05); however, no significant differences were observed in the comparisons of Datong versus Plateau, Datong versus Tianzhu, Tianzhu versus Gannan, Tianzhu versus Plateau, or Gannan versus Plateau yak breeds ( Supplementary Table S2 ). 3.3.

In contrast, BW at the end of feed withdrawal showed a highly significant treatment effect ( P = 0.0001).

More importantly, one-way ANOVA testing revealed a highly significant effect of flow rate on steady-state current ( F = 412.6, p < 0.0001), indicating that the current amplification observed between 0.1 and 10 μL min −1 is statistically robust.

According to analysis of inferred metagenomic functional content using PICRUSt algorithm, a highly significant discrepancy in metabolism and immune functions ( P < 0.0001) was predicted in the obese group.

The log ‐ rank test showed a highly significant result ( p < 0.0001), as depicted in Figures 2 and S1 .

Accordingly, here we detected a significant reduction in Hsp90 transcript levels of both isoforms in TGFβ-activated fibroblasts treated with mKate2 10K-EVs-CTPRAu, and a highly significant reduction (****p < 0.0001) by mKate2 100K-EVs-CTPRAu, 36 h after administration of EVs on TGFβ-activated fibroblasts (Figure 4 C-E).

Expression patterns of hsa-miR-181c and hsa-let-7c KRAS expression exhibited a highly significant, genotype-driven escalation across rs712 and rs9266 variants (p < 0.0001), revealing a clear molecular gradient: WT carriers maintained minimal KRAS expression, whereas HT patients displayed a dramatic surge the highest observed followed by a substantial, though slightly lower, increase in HM.

Exact p values are stated, unless highly significant different where they are listed as p <0.0001.