“highly significant”

RML-inoculated transgenic mice reached terminal disease after 400 ± 56 dpi (n = 10), whereas WTPrP C mice became terminally sick at 155 ± 1.6 dpi (n = 8), thus also showing a highly significant delay for PrP C GPIThy-1-expressing mice (Log Rank (Mantel-Cox)**** p <0.0001; S6A Fig ).

At 24 h, the difference in CFU between the combined treatment group and all other groups was highly significant ( p < 0.0001).

The most striking reduction of Glucosylsphingosine occurs right after the start of therapy (47.3%, p<0.001) and within the first 6 months (47.3%), although reduction over time is also highly significant (p<0.0001).

According to Table 3 , the model was highly significant ( P < 0.0001), and the lack of fit was not significant ( P > 0.05), which indicated that the regression equation was a good fit and the selected model was appropriate.

For salivary cortisol, male students exhibited a highly significant increase ( p < 0.0001) with a mean difference of 2.602 ng/mL between baseline and follow‐up samples, while female students also showed a significant increase ( p < 0.0001) with a mean difference of 2.950 ng/mL.

This showed that the difference between the screened and unscreened cohorts decreased from 46.3 to 19.8 months but remained highly significant ( P <0.0001; Figure 1F and Supplementary Figure 2 ).

As shown in Figure 2 a,b for the universal assay, we found a highly significant correlation (R 2 = 1.000, p < 0.0001 without; R 2 = 0.998, p < 0.0001 with added third-party DNA) between the numbers of HCK and axi-cel copies up to the lowest concentration.

A highly significant difference ( P < 0.0001) was observed in IL-4 production between Adj+pep 2nd and Peptide 2nd.

Meta-analyses Random-effects meta-analysis of trials of adding SGAs versus placebo to antidepressants yielded highly significant superiority of SGAs overall (OR = 1.59 [CI: 1.44–1.75]; z = 9.16, p < 0.0001; Figure 1(a) ).

Untreated cells (a) showed a highly significant difference (**** p < 0.0001) compared with all other groups.

This represents a highly significant seroma reduction (P=0.0001; two-tailed Fisher's exact test).

sustained response types between IC ipsi and IC contra in tinnitus GPs was highly significant [χ 2 (1) = 46.42, P < 0.0001].

The Top ICH genes had highly significant and similar associations within the primary cluster that included intratumoral densities of CD45 + (r = 0.53–0.67, all p < 0.0001), CD8 + T cells (r = 0.48–0.71, all p < 0.0001, Fig. 3 B), CD20 + B cells (r = 0.47–0.56, all p < 0.0001), and CD138 + cells (0.37–0.5, all p < 0.0001, Additional file 1 : Table S1).

The intercept was highly significant ( p < 0.0001), indicating a consistent baseline effect.

Highly significant differences (P < 0.0001) were observed in inflorescence length, seed diameter ( Figure 4 ), and hundred-seed weight.

Accordingly, spearman correlations between p-S65-Ub and PRKN protein levels in WT, Prkn +/- , and prkn -/- brains were positive and highly significant ( r = 0.72, p < 0.0001) (Fig.

The partial correlation between brain mass and time to weaning was highly significant even when body mass was controlled for (original r (67) = .87, p<.0001, r partial = .69, p<.0001) and the influence of phylogenetic relatedness between the species on the correlation between brain mass and time to weaning post conception was minor ( Materials and Methods ; Fig.

Statistical analysis revealed highly significant differences between the control group and both the Recoveron and methanolic propolis extract-treated groups ( p < 0.0001 in both cases).

altitude broad‐leaved forest shrub diversity soil physicochemical variables vegetation belts Jilin Provincial Science and Technology Development Plan Project 20240303095NC YDZJ202102CXJD032 At lower altitudes (300–1050 m), both the vegetation belt and altitude had highly significant effects on the diversity and abundance of pathogenic fungi (Table 1 , ANOVA, F = 26.776, 18.164, 18.161, and 20.018; p < 0.0001).

The equation developed through the regression is as follows: Percent cover of ISA = 0.0795 (radiance) + 0.00868 (population count) The regression had an r 2 squared of 0.59 and is highly significant p <.0001.

, 2019 ), the correlation between hangover frequency and severity was highly significant ( r = 0.710, P < 0.0001), suggesting reverse tolerance.

4A ), and a GLM with total tissue nitrogen and species as factors is highly significant ( F (7,24) = 35.3, P < 0.0001, R = 0.97).

Analysis of spectra counts showed a highly significant elevation of immunoglobulins in MS CSF ( Figures 5B , ANOVA p < 0.0001).

2 ) shows a very good fit to the data and all models were highly significant (p<0.0001, Table 3 ).

Both fungal strains (S2 and S3) caused a highly significant mortality to the ants when applied at high doses in the challenge ( Fig. 1 and Table 1 ; C-C vs C-S2, early challenge: d.f. = 3.9, P <0.0001, late challenge: d.f. = 3.3, P <0.001; C-C vs C-S3, early challenge: d.f. = 5.1, P <0.00001, late challenge: d.f. = 4.1, P <0.0001).