“highly significant”

Beta diversity based on Bray-Curtis dissimilarity showed significantly different community compositions by parity ( p < 0.05) in the first year of infant life, with parity-based community variation being highly significant at 2 months of life ( p = 0.0001) and this significance disappearing by 24 months of life ( Figure 1 ).

Overall, the presence of this fusion transcript represents a highly significant novel association with the SHIP1-deficient phenotype, with a conservatively estimated odds ratio (OR) of 153.0 (95% CI: 5.562–4209, P < 0.0001) compared to the healthy 13 controls, and an OR of 606.3 (95% CI: 22.76–16,150, P < 0.0001) compared to all available SHIP1-sufficient IBD and healthy control subjects ( n = 53).

In parallel, in all cases there was also a highly significant ( p < 0.0001) increase in viscosity.

Moreover, we found that it was correlated (using Spearman correlation) with the GC content of the region (corr = 0.13), the fraction of region that was protein coding (corr = 0.26) and the level of gene expression (only available for 71% of genes; corr = 0.20), all highly significant ( P < 0.0001).

We observed a highly significant difference between the distance traveled by P-42 and the distance traveled by any of the Aβ monomers, with P < 0.0001 for all three comparisons, respectively ( Fig 2F ).

The differences between the mean STAT, MAT, and IHA titers of infected cattle and healthy vaccinated cattle were highly significant (p<0.0001, p<0.005, and p=0.0002, respectively).

Logistic regression provided a good description of the data for both populations and accession effects were highly significant ( p ≤ 0.0001).

The impaired ability of the Exon 12 −/− mice to run on the rotorod at greater than moderate speeds is the most obvious and highly significant phenotype of the behavioral testing ( P < 0.0001).

The mean differences between the two groups were highly significant ( t = 11.01, p < 0.0001 and t = 7.90, p < 0.0001 for 2016-off and 2016-main seasons, respectively) indicating that SrH confers significant effects on disease severity reduction in addition to conferring a resistant infection response.

The difference between these groups was highly significant ( p < 0.0001), which underscores the substantial impact of modifiable clinical, psychological, and social determinants on brace-wearing behavior.

Unpaired t-tests comparing the seronegative and seropositive populations yielded highly significant p-values (p<0.0001) for both the Immunetics® C6 Lyme ELISATM ( Fig 2A ) and the MicroB-plex Anti-C6/Anti-pepC10 Immunoassay ( Fig 2B ).

Specifically, p < 0.05 indicates a highly significant difference, while p < 0.0001 denotes an extremely significant difference, and p > 0.01 suggests no significant difference.

398 genes were shared between the groups, showing highly significant (p<0.0001, Chi-square test) enrichment of genes regulated by ΔNp63α re-expression among differentially expressed genes during EMT.

The associations of ap2-g and gexp-5 transcript abundance with gametocyte production remained highly significant after adjustment for gametocyte density at the time of measurement ( p < 0.0001).

At the same time, higher LGR4 positivity was observed in the normal mucosa than in the tumour tissue, with a highly significant difference (93% and 36%, P<0.0001).

In V1, the effect of eccentricity on BOLD response was highly significant ( F (1,23898) = 37.8; p < 0.0001; Cohen's f 2 = 0.319), indicating a strong relationship.

The CC group showed no significant increase in cortisol during stress or drug cue exposure, while the CG group showed a highly significant increase in their cortisol response during stress ( t =4.25, df=109, P <0.0001, Cohen's d =1.46) and drug cue ( t =3.04, df=109, P =0.003, Cohen's d =1.04) relative to the neutral condition ( Figure 2 ).

The principal symptom in all patients was hip pain, with onset of a median of 3 years (IQR 7) before THR in patients with RPOH, compared to the median of 5 years (IQR 19) in POH; thus there was a highly significant difference in disease onset ( P = 0.0001, Mann–Whitney test, Fig. 4 A).

Using GREAT, we found that about 77% of the genes associated with active TFAP2A peaks are also associated with active MITF peaks, a highly significant overlap (hypergeometric test, p<0.0001) ( Fig 3D ).

The regression was highly significant statistically ( F = 3935.97; df = 1, 43; p < 0.0001; R 2 = 0.99).

In Tvedestrandsfjord, which included five replicate egg samples but no adults, there was a highly significant heterogeneity among temporal samples in proportions of the two types ( p < 0.0001: Table 1 ).

The effect was highly significant in the crude model ( β = −1.445; P < .0001) and, after full adjustment in Model 2, showed a strong trend that approached statistical significance ( β = −0.401; P = .091).

Outcome of APE treatment In terms of APE results, there was a highly significant decrease in the mean PAP from 35.5±6.5815 to 19.7±4.943 mmHg (P<0.0001) ( Figure 3 ), in the shock index from 1.089±0.177 to 0.678±0.088 (P<0.0001), and in the MS from 18.05±2.502 to 9.05±2.929 (P<0.0001).

A one-way mixed model was applied with mean pain ratings as the response, the result showed that the contrasts HC and LC condition was highly significant (p<0.0001).

The remaining 167 F 2 lines showed a highly significant ( P < 0.0001) effect on flowering associated with the SSR markers flanking the HvFT1 locus.