In this group, antibody levels were detected from 14 dpv, showing a highly significant increase ( p < 0.0001) from this timepoint until the end of the study.
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Hydroxyl radical generation measured by HPF fluorescence increased significantly at all tested time points (Figure S3a ; GLM, p < 0.0001 at 5 min, p = 0.0012 at 10 min, and p = 0.0002 at 30 min), while hydrogen peroxide generation remained highly significant throughout visible‐light irradiation (Figure S3b ; GLM, p < 0.0001 at 5, 10, and 30 min), indicating the involvement of multiple ROS pathways in the photodynamic process.
The Pairwise G-tests showed that genetic differentiation was highly significant between the sorghum populations of the three groups, being highest between the Chuka and both the Tharaka (p-value < 0.0001) and Mbeere (p-value = 0.0002) populations and lowest between the Tharaka and Mbeere populations (p-value = 0.0083).
When comparing users to their friends, this correlation is highly significant with a p ≤ 10 - 4 .
This association is highly significant ( p < 0.0001) when compared to a simulated random-breakage model.
Whereas phagocytosis in the presence of heat-inactivated serum from NHD showed no significant association with LPC concentrations (not shown), a highly significant negative correlation ( r = –0.556, p < 0.0001) between LPC levels and phagocytosis in case of heat-inactivated serum from patients with SLE was observed (Figure 5 B).
There was a highly significant relationship between reduction in ESV and SDI (P<0.0001) as well as a greater than 15% improvement in EF and SDI (P<0.0001) (see figure 1 and table 1 ).
There are highly significant (P<10 –4 ) differences in BAS Naming Vocabulary Score between groups, with both sub-fertile and ART groups having higher mean scores than the controls.
There were, however, highly significant differences between groups in the extent of this decline ( p < 0.0001 for the interaction between treatment and time, see Fig. 1 A).
The differences were highly significant (P < 0.0001) between the fish oil group and all vegetable oils groups.
Highly significant differences were observed for PCA in PC1 (p < 0.0001) and for PCoA (p < 0.0001).
Anal vaccinated group showed full protection, which is highly significant relative to the un-vaccinated control group (P<0.0001 and P = 0.0005, respectively).
Each species also showed a highly significant ( p < 0.0001) preference for nestmate recruitment pheromone at 0.1 bee equivalents (Fig. 3 ; T. hyalinata , 80% choosing the feeder with pheromone; T. spinipes , 65%).
In most cases, the differences were highly significant ( p < 0.0001).
This observation was confirmed by the two-way PERMANOVA, which crossed swabbed region with health, stating that there were highly significant differences between regions and globally between health states (pseudo- F = 22.241, p -value = 0.0001, pseudo- F = 10.373, p -value = 0.0001, respectively) (Supplementary Table S1 ).
Statistical testing showed highly significant differences in both the SD and IQR, giving p -values of <0.0001.
A highly significant difference was observed during gait and the other movements ( p < 0.0001).
During the spring, at the ringing station in north-central Hungary (Ócsa) where the highest number of tick-infested birds were caught and which contributed the most balanced ratio of birds with different migratory habits to the study, there was a highly significant ( P < 0.0001) difference between the host associations of I. ricinus and H. concinna , since the former predominated on resident and short-distance migrant bird species, but H. concinna on long-distance migrants.
A highly significant correlation was observed between DFA and MAGE (r = 0.68, p < 0.0001): high variability correlated with high DFA (and thus, low complexity) ( Figure 3 ).
Two-way ANOVA shows highly significant differences [F(1,24)=31.5, p<0.0001] between HAT genes expression in controls and embryos injected with well described Dystrophin morpholino cocktail (also see Materials and methods, S1 Fig A ).
Urea, ALT, AST and AFP were highly significant in post-hepatitic HCC patients than control group (P ≤0.0001).
The ANOVA results ( Table 5 ) show that the model was highly significant ( p < 0.0001) for FRAP and DPPH values.
The comparison of regional deformation parameters measured in subsequent left ventricular segments indicated highly significant linear relationship of values from both methods ( p < 0.0001), although correlation coefficients for measurements performed at baseline were slightly higher than during peak stage of dobutamine test.
Fitting a generalized linear model with negative binomial errors to the data on number of thalli per individual from infected nests (fitted dispersion parameter θ = 4.39) showed a highly significant difference between nests in the level of infection (Wald χ 2 = 245.05, df = 1, p < 0.0001), and also a strong effect of estimated worker age (Wald χ 2 = 70.3, df = 4, p < 0.0001), with older workers having a higher load of thalli (Fig. 7 ), but no association with the presence or absence of P. alcon caterpillars (Wald χ 2 = 0.719, df = 1, p = 0.396).
Bold values indicate highly significant main effect of infection (p < 0.0001), asterisks indicate significant time by infection interaction, and italics indicates no significant main effect (significant interaction only).