“highly significant”

Both tools showed highly significant change during the study (p<0.0001 for each), but agreement between the change in the two tools was only fair (κ=0.31).

The breadth of the responses to the 11 epitopes showed highly significant correlations with both lower pVLs ( P < 1 × 10 −4 ; r = −0.4909) and higher CD4 counts ( P < 1 × 10 −4 ; r = 0.4542) in these Japanese individuals ( Fig. 8B ).

Although there were no marked differences between the groups, BDNF levels tended to increase immediately after exercise in both the PLA ( p < 0.001) and GTE (no significant changes) groups as well as post 1 h of recovery in both PLA ( p < 0.05) and GTE (no significant changes) groups, compared to values recorded at rest as reflected by a highly significant time effect (F = 13.73, p < 0.0001; η 2 = 0.49).

A linear regression model fitted with HbA1c reduction as the outcome and baseline HbA1C as the predictor demonstrated a highly significant relationship R 2 =0.74; p<0.0001 ( figure 4 and online supplemental file 6 ).

Between group comparisons revealed a highly significant difference in antibody concentrations for male rats compared to female rats at weeks 8 ( p < 0.0001) and 10 ( p < 0.01).

The mean value of GPx in the present study was 16.46 U/g Hb before supplementation and 4.53 U/g Hb after, and paired t -test showed the differences in GPx, GSHt and GSH/GSSG ratio to be statistically highly significant ( p <0.0001).

Among the two hiPSC lines, the highly significant ( P < 0.0001, paired t test with Bonferroni correction) reductions in methylation observed for the donor L1 during hiPSC derivation (25.0% on average) far exceeded that seen for the lineage progenitor (12.5%) and L1-Ta subfamily (2.9%) ( Fig. 5C and 6B ).

Although a statistical comparison of these two subgroups was not included in the original paper, we performed this comparison using data provided in the manuscript, which was statistically highly significant (Fisher’s exact test; p = 0.0001).

This difference was highly significant ( p < 0.0001) while no significant differences in sRAGE levels were found between primary and secondary APS ( Figure 4B ).

Highly significant differences in the transmission rate (% C Las-positive inoculated leaves) were found between various lines ( Table 6 , P = 0.0001).

Differences considered significant when p < 0.05 (*), very significant when p < 0.01 (**), highly significant when p < 0.001 (***), and extremely significant when p < 0.0001 (****).

Under cold conditions, the analysis revealed a highly significant effect of genotype ( p < 0.0001), indicating that Salinas consistently exhibited higher germination than US96UC23 across all time points ( Figure 1 b).

IAb levels from the confirmatory visit for all three IAb types were highly significant ( p <0.0001) with ORs of 1.36 (95% CI 1.25, 1.47), 1.32 (95% CI 1.22, 1.44) and 1.15 (95% CI 1.07, 1.24) for IA-2A, GADA and IAA, respectively.

We observed a highly significant correlation between both assays (r = 0.78, p<0.0001, Fig 2D ), indicating that HIV-Flow and mRNA Flow FISH provide similar estimates of the size of the translation competent reservoir in clinical samples.

Thus, ANOVA showed a highly significant line × FS interaction ( p < 0.0001; Table 2 ) and notably, pairwise post hoc contrasts revealed that the basal level of BDNF-LI of RLAs was markedly lower (−69%) than that of the RHAs ( p < 0.0001; Figure 3 ).

The median score in the P − group was 20.7 [14.2–28.1] compared to 47.9 [39.1–56.8] in the P + group, a difference that was highly significant (Mann–Whitney U test, p < .0001).

As shown in Figure 4 , the diagnostic power of C6Ma1 and C6Ma3 was highly significant with an AUROC of 0.90 ( P < .0001) and of 0.87 ( P < .0001), respectively when comparing healthy control to patients with cancer.

Despite age, sex, and procedural differences there was remarkable consistency in that in all 29 subjects, PAPP‐A levels in the conditioned medium of epicardial preadipocytes greatly exceeded those of subcutaneous preadipocytes, resulting in a highly significant 15‐fold difference by paired t ‐test ( P < 0.0001).

Weather Data Statistical analysis of weather data for the two seasons revealed significant differences in climatic parameters between 2020 and 2021, including temperature and rainfall, where the difference was highly significant between the two seasons ( p < 0.0001).

It was observed that there was a highly significant ( P = 0.0001) association (r = 0.75) between infection with hrHPV types and the development of SIL.

Also association of stigma with quality of life showed highly significant findings in both genders (p< 0.0001) on all the domains of DLQI.

Determinants of TRAP AUC For AUC04 and AUC06, insulin was strongly positively associated with TRAP, with a modest negative association between TRAP and glucose and a weak association between TRAP and vitamin C, with the overall models being highly significant ( p < 0.0001) and explaining about 32% of the variation in TRAP.

The analysis of variance revealed highly significant effects ( p < 0.0001) of pruning wound age, fungal species, and their interaction on lesion development in both experimental years.

Analysis of GMFI revealed parallel results, with highly significant MOI effects in MDA-MB-231 (F(2,6) = 427.7, p < 0.0001) and MDA-MB-468 (F(2,6) = 297.6, p < 0.0001), confirming robust dose-dependent increases in bacterial load, whereas MDA-MB-453 exhibited negligible changes.

After statistical analysis, the F -value of the APS of the lignin nanoparticles model is 230.57, all of which are highly significant ( p -value < 0.0001), and the p -value of the lack-of-fit term is not significant ( p > 0.05), suggesting that the model is accurate and reliable.