“highly significant”

Overall, the presence of this fusion transcript represents a highly significant novel association with the SHIP1-deficient phenotype, with a conservatively estimated odds ratio (OR) of 153.0 (95% CI: 5.562–4209, P < 0.0001) compared to the healthy 13 controls, and an OR of 606.3 (95% CI: 22.76–16,150, P < 0.0001) compared to all available SHIP1-sufficient IBD and healthy control subjects ( n = 53).

LKES in the third postoperative week showed statistically highly significant improvement ( P = 0.0001). 9 However, in the study by Rudmik et al. 16 where dexamethasone eluting spacer was used, endoscopic evaluation in the fourth postoperative week showed no significant difference on LKES between treatment and control group with an equivalent range of 2–10.

The CK19 analysis helped us to exclude adenocarcinomas versus tuberculosis, transudates, and parapneumonic effusions with a highly significant P value (Dunn's test, P < 0.0001), as shown in Table 2 .

Results Similar MIC interpretations for tetracycline, erythromycin, and ciprofloxacin were found in 97%, 98.5%, and 100% of the isolates, respectively, indicating a good level of agreement between Etest and Sensititre ( p < 0.0001); additionally, the correlation between the two methods was highly significant for the three tested antibiotics ( p < 0.0001).

We found that full spectrum SEF95 showed highly significant differences between pre- and post- LOR ( p < 0.0001).

ANOVA indicated a highly significant ( p < 0.0001) difference in the average percentage of window filtered Sum Vector Magnitude among low-/high-acceleration ADLs and fall.

Highly significant (p < 0.0001) and close (Spearman r = -0.91) correlation between binding affinities determined by SPR and the mol% binding determined in the pull-down assays was observed for the interactions of both wild-type (closed symbols) and ΔH C loop-mutant (open symbols) H C B (triangles), H C DC (squares), and H C G (circles).

The exact G test for differentiation indicated that, on average, differences in allele frequency distribution among populations were highly significant (exact p value ≤0.0001).

Inoculation response and patterns of variation The average response to inoculation over all trials was estimated at 115 kg/ha and was highly significant (model 1 a , p < 0.0001).

In our study, we observed a highly significant increase ( Table 2 : p ≤ 0.0001; FC = +8.187) in hypoxanthine excretion in all 20 cases studies, which peaked at one hour after alcohol consumption in 18 of the cases, and at 2 hours in the other two cases ( Fig 4E ).

melliferum populations were more stable year to year ( P = 0.0544) but showed highly significant seasonal variation ( P < 0.0001).

The spine density per 100 μm of dendrite was 30.7 ± 3.7, compared to corresponding values of 15.9 ± 5.1 for the GRPR cells 18 , and this difference was highly significant ( P < 0.0001; t-test; Fig. 8 e).

The difference in frequencies of variants within cline centre groups between the filtered (SCV only) and unfiltered datasets was highly significant (European taurine S1: Χ 2 = 13,151, df = 2; p < 0.0001; African taurine S1: Χ 2 = 17,118, df = 2; p < 0.0001), indicating an enrichment of variants with restricted gene flow and unbiased introgression.

The heterogeneity test was highly significant (Q = 229.76, df. = 25, p value <0.0001).

There was a highly significant correlation between responses to the two artemisinin derivatives ( P <0.0001).

This reduction of the ADT with time was highly significant for both species (Table 3 ; P < 0.0001).

The linkage disequilibrium between the two EQ mutations (at codon positions 155 and 190) and allozymes was highly significant ( Table 1 ), with correlation coefficients (R ij ) greater than 70% ( p -values < 0.0001).

A highly significant association between the presence of p53 gene mutation and nuclear accumulation of p53 protein was found ( P < 0,0001).

There was a highly significant difference between the coverage distributions at overmerged sites versus the rest of the sites (Kolgomorov–Smirnoff D: 0.5331, p < 0.0001).

Nest growth was a reliable predictor of nest productivity: we found a highly significant, positive correlation between brood value at worker maturation and nest growth (Fig. 3 ; LM, t = 5.85, p < 0.0001).

A logistic regression analysis revealed this to be a highly significant difference (b = 2.74, 95% CI = [1.94, 3.54], z = 6.7, p < 10 −4 ).

The heterogeneity across studies was substantial and highly significant (I2 = 99%, P < 0.0001), indicating that the observed variability was not due to chance alone.

In particular, there was a highly significant linkage disequilibrium between rs3744337 and rs3744335 (r 2 = 0.72; P < 0.0001) within HS3ST3A1 ; there was also a highly significant linkage disequilibrium between rs2072243 and rs2072242 (r 2 = 0.64; P < 0.0001) within HS3ST3B1 .

We conducted a sphere formation assay on agarose-coated plates, which minimized cell adherence to the surface, and observed a highly significant increase ( p < 0.0001) in the number of spheres formed in the groups; BDFO and BNFO, respectively, as compared to the control group, BNFN whereas FDBO and FNBO cells did not show any considerable change (Fig. 4 a, b ).

Studies of lesions of patients with borderline leprosy have revealed strong correlations between TGF-β and NGF, and TGF-β and NGF-R ( r = 0.8722 and r = 0.7257, respectively), with highly significant p -values for the two correlations ( p < 0.0001 and p = 0.0015, respectively) ( 48 , 49 ).