“highly significant”

Indeed, we found a highly significant correlation between latency and rise time ( n = 42, R 2 = 0.43; p < 0.0001) and rise and decay time ( n = 42, R 2 = 0.21; p = 0.002).

A highly significant ( p < 0.0001) positive correlation was identified for the %DevLep with CCL4 WCS and a negative correlation for %SSS with S100A12 Med and S100A12 WCS ( Supplementary Table 1 ).

All of the exposures caused increases in mutant frequencies relative to vehicle-matched controls (Supplementary Table 2 ), and the results were highly significant ( P < 0.0001) for BaP (122.9-fold), PRC (9.7-fold), and ENU (7.2-fold).

A chi-square test comparing these seven entirely non-compliant staff to the 705 who wore at least one protective item yielded a highly significant result (χ2 = 684.28, p < 0.0001), indicating that complete non-compliance was far less common than expected by chance.

A highly significant increase of both anti-al34k2 IgG1 and IgG4 levels was observed in PD2 by pairwise comparisons between paired samples ( n = 68, p < 0.0001; Figure 4B ); instead, only IgG4 levels showed a weakly significant increase after summer when all samples were considered ( p = 0.0326, Figure 4A ).

Judging from the magnitudes of the log-hazard ratios, nodal status is more influential than the T stage in predicting survival, although both are highly significant ( p < 0.0001).

Full details of the terms are given in Additional file 4 : Tables S3-S8. As a confirmation of the validity of the RNA-seq transcript abundance estimates, a highly significant positive correlation (r = 0.9119, P < 0.0001) was found between the RNAseq and qRT-PCR datasets derived from the abundance of six transcripts in three population samples, Trento, Athens and Ban Rai (Additional file 5 : Figure S2, Additional file 6 : Table S9).

As the probability (p-) column indicates, all main effects—distracter level, formant swing extent, the size of f0 separation, and assignment of the higher f0 to target or distracter—were highly significant with p = 0.0001, both within and across subjects.

Degradation of acrylamide ( Figure 6 ) proved to be highly significant (**** p < 0.0001) after 3 (1100 ± 18 μg kg −1 ) and 6 months (490 ± 7 μg kg −1 ) of storage compared to that acrylamide content in the fresh samples (1400 ± 11 μg kg −1 ).

Similarly, urea concentrations increased stepwise across groups, with significant differences between non-T2D and T2D patients ( p < 0.05) and highly significant increases in T2D-DR patients compared with both groups ( p < 0.0001) ( Figure 1 B).

Unsurprisingly, participants in the 10-h variation slept for longer (7 h 6 min, SD = 38 min) than those in the 6-h variation (4 h 45 min, SD = 28 min), a difference which a two-tailed t test showed was highly significant, t (47) = 14.66, p < .0001, Cohen’s d = 4.34.

The two‐way ANOVA on square‐root arcsine transformed data showed highly significant effects of dose ( F 1,32 = 26.79, p < .0001) and of the interaction between dose and accession ( F 1,32 = 20.39; p < .0001), but not of accession ( F 1,32 < 0.42; p = .52), and the residuals from this model did not deviate from normality ( W = 0.95, p > .12).

A highly significant difference was observed between the untreated cells and the positive control (**** = P <0.0001), which served as the reference for 100% cytotoxicity, validating the assay and enabling data normalization.

This expectation agrees with the experimental data (see Fig 3D ), as the average rate of the autonomous firing of prototypic neurons (18.0 spikes/s) was higher than that of arkypallidal neurons (5.1 spikes/s), and this difference was highly significant (p = 0.0001, unpaired t-test).

ecuadoriensis , the square root area - but not the perimeter - showed a highly significant reduction (permutation test, 1000 cycles, P < 0.0001) in the late developmental stage.

Both our cohort and that of Morris et al had a highly significant paired 2-tailed t test for Na + 1 ≠ Na + 2 ( P < 0.0001).

This observation is corroborated statistically by two-sided sign tests, revealing that the difference between agreement in case of voluntary and enforced implementation is highly significant for contact-tracing apps, vaccination, and contact limitations ( P < 0.0001) but insignificant for travel restrictions ( P = 0.622) and masks ( P = 0.389).

In all cases, the slope of the regression was highly significant ( p < 0.0001), and the R 2 was between 0.36 and 0.39.

We further applied a permutation procedure to establish the statistical significance of such prediction accuracies against the chance level, and both turned out to be highly significant ( p < 0.0001 for females and p < 0.001 for males).

Concerning the grazing area generated from uni-versus multinucleate amoebae, an unpaired t test, two-tailed, with Welch’s correction has been executed with GraphPad Prism Software (San Diego, CA, USA) to compare the grazing distribution that is highly significant (p value < 0.0001).

GDF-15 showed the most robust response, with highly significant main effects for both time and dose and a strong interaction ( p < 0.0001).

After chemotherapy, we observed a highly significant decline of DNA content in the LMWF to a median value of 380 ng/ml (range 40 – 1790 ng/ml) (p = 0.0001).

AUSTRAL medium) had a highly significant effect on the variability of SBF indexes (Wald = 83.73, **** P < 0.0001) (Table 2 ).

Comparison of survival curve using a log-rank (Mantel–Cox) test showed a highly significant difference between mice treated with control ATCs and mice treated with CD33GO BATs (p < 0.0001), control ATCs vs.

subjects who ate no seafood, these differences were highly significant ( p < 0.0001) with Hg levels that were higher 3–7-fold in maternal hair, 7–8-fold in maternal blood, 4–6-fold in the placenta, and >10-fold in cord blood.